scholarly journals In Vitroandin VivoEvaluation of the Efficacy of Bovine Colostrum against Human Rotavirus Infection

2010 ◽  
Vol 74 (3) ◽  
pp. 680-682 ◽  
Author(s):  
Mizuho INAGAKI ◽  
Mayumi YAMAMOTO ◽  
XIJIER ◽  
CAIRANGZHUOMA ◽  
Kenji UCHIDA ◽  
...  
Keyword(s):  
Bovine Colostrum ◽  
Rotavirus Infection ◽  
Human Rotavirus

scholarly journals Effectiveness of live attenuated monovalent human rotavirus vaccination in rural Ecuador, 2008-2013

2018 ◽  
Author(s):  
Alicia N. M. Kraay ◽  
Edward L. Ionides ◽  
Gwenyth O. Lee ◽  
William F. Cevallos Trujillo ◽  
Joseph N.S. Eisenberg
Keyword(s):  
Indirect Effects ◽  
Cox Regression ◽  
Age Groups ◽  
Community Setting ◽  
Population Level ◽  
Population Based ◽  
Case Control ◽  
Rotavirus Infection ◽  
Human Rotavirus ◽  
Overall Effectiveness

AbstractBackgroundWhile live attenuated monovalent human rotavirus vaccine (Rotarix) efficacy has been characterized through randomized studies, its effectiveness, especially in non-clinical settings, is unclear. In this study, we estimate direct, indirect, and overall effectiveness of Rotarix vaccination.MethodsWe analyze 29 months of all-cause diarrhea surveillance from a child cohort (n=376) and ten years of serial population-based case-control lab-confirmed rotavirus data (n=2489) from rural Ecuador during which Rotarix vaccination was introduced. We estimate: 1) the direct effect of vaccination from a cohort of children born from 2008-2013 using Cox regression to compare time to first all-cause diarrhea case by vaccine status; and 2) the overall effect on all-cause diarrheal and symptomatic and asymptomatic rotavirus infection for all age groups, including indirect effects on adults, from the case-control data using weighted logistic regression.ResultsRotarix vaccination provided direct protection against all-cause diarrhea among children 0.5 - 2 years (All-cause diarrhea reduction for receipt of 2 doses of Rotarix=57.1%, 95% CI: 16.6, 77.9%). Overall effectiveness against rotavirus infection was strong (Exposure to 100% coverage of Rotarix vaccination was associated with an 85.5% reduction, 95% CI: 61.1-94.6%) compared to 0% coverage. Indirect effects were observed among older, vaccine-ineligible children and adults (84.5% reduction, 95% CI: 48.2-95.4%). Vaccine effectiveness was high against both symptomatic (48.3% reduction,95% CI: 0.03-73.1%) and asymptomatic infection (90.1% reduction, 95% CI: 56.9-97.7%).ConclusionsRotarix vaccination suppresses overall transmission. It is highly effective among children in a rural community setting and provides population-level benefits through indirect protection among adults.

Influence of Temperature and Relative Humidity on Human Rotavirus Infection in Japan

1983 ◽  
Vol 147 (1) ◽  
pp. 125-128 ◽  
Author(s):  
T. Konno ◽  
H. Suzuki ◽  
N. Katsushima ◽  
A. Imai ◽  
F. Tazawa ◽  
...  
Keyword(s):  
Relative Humidity ◽  
Influence Of Temperature ◽  
Rotavirus Infection ◽  
Human Rotavirus

scholarly journals Human rotavirus infection

1984 ◽  
Vol 6 (8) ◽  
pp. 55-57
Author(s):  
Petrie Rainey ◽  
Mary York
Keyword(s):  
Rotavirus Infection ◽  
Human Rotavirus

Human Rotavirus Infection in Efate, Vanuatu

1982 ◽  
Vol 31 (1) ◽  
pp. 136-141 ◽  
Author(s):  
H. G. Williamson ◽  
C. M. Boveington ◽  
P. H. Bennett ◽  
C. J. Birch ◽  
T. Kuberski ◽  
...  
Keyword(s):  
Rotavirus Infection ◽  
Human Rotavirus

Human rotavirus infection in infants and young children with intussusception

1978 ◽  
Vol 2 (3) ◽  
pp. 265-269 ◽  
Author(s):  
Tasuke Konno ◽  
Hiroshi Suzuki ◽  
Toyoko Kutsuzawa ◽  
Aki Imai ◽  
Noriko Katsushima ◽  
...  
Keyword(s):  
Young Children ◽  
Rotavirus Infection ◽  
Human Rotavirus ◽  
Infants And Young Children

MicroRNA profile analysis of host cells before and after wild human rotavirus infection

2016 ◽  
Vol 88 (9) ◽  
pp. 1497-1510 ◽  
Author(s):  
Yan Zhou ◽  
Jinyuan Wu ◽  
Panpan Geng ◽  
Xiang Kui ◽  
Yuping Xie ◽  
...  
Keyword(s):  
Profile Analysis ◽  
Host Cells ◽  
Rotavirus Infection ◽  
Human Rotavirus ◽  
Before And After ◽  
Microrna Profile
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