The evaluation of efficacy of acupuncture and homeopathy in complex treatment of the patients with arterial hypertension

10.12737/7223 ◽  
2014 ◽  
Vol 8 (1) ◽  
pp. 0-0
Author(s):  
Поспелова ◽  
A. Pospelova ◽  
Михайлова ◽  
A. Mikhaylova

The high prevalence of hypertension requires the development of new approaches to the treatment of this pathology. The purpose of this work is to evaluate the efficacy of complex treatment of patients with arterial hypertension stage I and II with by means of the injections of antihomotoxic medicaments in acupuncture points and the using only standard pharmacotherapy. The patients were divided into 2 study groups: the first group of patients received a comprehensive therapy with homeopathy and acupuncture, the second group (con-trol group) received only standard pharmacotherapy. For objectification of the results of treatment, patients were examined: REG, USDG of the brain vessels, Holter monitoring of blood pressure, ECG, cholesterol, and triglyceride levels, clinical and psychological research (MMPI), as well as electro-punctural Voll diagnostic. It was found that the effectiveness of treatment in the study group was significantly higher than in control group. It was established significant dynamics of blood pressure parameters, improvement the results of the ultrasound diagnostics of the brain vessels, decrease of cholesterol, LDL cholesterol, triglycerides, decrease the severity of anxiety, fatigue, normalization of the skin conductivity in the points of the meridians "Circula-tion" and "Nervous system". The significant improvement was in 98.6% of patients, and in 86.5% of the control group.

2020 ◽  
Vol 26 (3) ◽  
pp. 63-67
Author(s):  
A. V. Dubovaya ◽  
Уи.V. Naumenko

The prevalence of arterial hypertension in children ranges from 1 to 25 %, depending on age and the selected criteria. Vitamin D can affect blood pressure (BP) through several mechanisms. The most important function of vitamin D is its role in the regulation of the renin-angiotensin-aldosterone system. The only metabolite of vitamin D that is used to determine its content in the human body is 25 (OH) D (calcidiol). The data on the effect of vitamin D on blood pressure in adolescents are contradictory, indicating a lack of knowledge of this issue. Objective: to evaluate the effectiveness of the use of an aqueous solution of vitamin D3 in the complex treatment of children with essential hypertension. Materials and methods. We examined 30 children (24 boys and 6 girls) aged 13 to 17 years with essential hypertension who had a deficiency of 25 (OH) D in blood serum, the treatment complex of which was supplemented with an aqueous solution of vitamin D3 at 1500 IU/day for 3 months. The control group consisted of 30 children (20 boys and 10 girls) with essential hypertension who received standard therapy. Results. In the main group, after 3 months of taking colecalciferol, a statistically significant normalization of vitamin D levels was documented in 15 (50.0 %) patients, an average of 33.26±1.2 ng/ml. Vitamin D deficiency persisted in 8 (26.6 %) children, vitamin D deficiency persisted in 7 (23.3 %) patients, which served as a basis for increasing the dose of colecalciferol to 2000 IU and continuing to take the drug for another 1 month with a reevaluation serum 25 (OH) D content. A study of the dynamics of blood pressure with the addition of complex treatment with colecalciferol showed that in 24 (80.0 %) children the level of blood pressure decreased, which was statistically significantly more often in comparison with the control group (53.3 %, p<0.05): systolic blood pressure decreased from 142.6±2.4 mm Hg up to 125±0.6 mm Hg (p<0.05), diastolic blood pressure – with 80.2±1.3 mm Hg up to 78.5±1.5 mm Hg. Normalization of blood pressure in the main group was detected after 31±4 days, while in the control group after 60±7 days (p<0.05). There were no adverse reactions during treatment. Conclusions: The positive effect of the drug is proved, which consists in restoring the normal content of 25 (OH) D in blood plasma and reducing systolic blood pressure.


2021 ◽  
Vol 12 ◽  
Author(s):  
Agnieszka Jurek ◽  
Paweł Krzesiński ◽  
Grzegorz Gielerak ◽  
Przemysław Witek ◽  
Grzegorz Zieliński ◽  
...  

BackgroundCushing’s disease is a rare condition associated with a high cardiovascular risk and hypercortisolemia-related hemodynamic dysfunction, the extent of which can be assessed with a noninvasive method, called impedance cardiography. The standard methods for hemodynamic assessment, such as echocardiography or ambulatory blood pressure monitoring may be insufficient to fully evaluate patients with Cushing’s disease; therefore, impedance cardiography is being currently considered a new modality for assessing early hemodynamic dysfunction in this patient population. The use of impedance cardiography for diagnosis and treatment of Cushing’s disease may serve as personalized noninvasive hemodynamic status assessment and provide a better insight into the pathophysiology of Cushing’s disease. The purpose of this study was to assess the hemodynamic profile of Cushing’s disease patients and compare it with that in the control group.Material and MethodsThis observational prospective clinical study aimed to compare 54 patients with Cushing’s disease (mean age 41 years; with 64.8% of this population affected with arterial hypertension) and a matched 54-person control group (mean age 45 years; with 74.1% of this population affected with arterial hypertension). The hemodynamic parameters assessed with impedance cardiography included the stroke index (SI), cardiac index (CI), systemic vascular resistance index (SVRI), velocity index (VI), (ACI), Heather index (HI), and thoracic fluid content (TFC).ResultsThe Cushing’s disease group was characterized by a higher diastolic blood pressure and a younger age than the control group (82.9 vs. 79.1 mmHg, p=0.045; and 41.1 vs. 44.9 years, p=0.035, respectively). Impedance cardiography parameters in the Cushing’s disease group showed: lower values of SI (42.1 vs. 52.8 ml/m2; p ≤ 0.0001), CI (2.99 vs. 3.64 l/min/m2; p ≤ 0,0001), VI (42.9 vs. 52.1 1/1000/s; p=0.001), ACI (68.7 vs. 80.5 1/100/s2; p=0,037), HI (13.1 vs. 15.2 Ohm/s2; p=0.033), and TFC (25.5 vs. 27.7 1/kOhm; p=0.006) and a higher SVRI (2,515 vs. 1,893 dyn*s*cm-5*m2; p ≤ 0.0001) than those in the control group.ConclusionsCushing’s disease is associated with significantly greater vasoconstriction and left ventricular systolic dysfunction. An individual assessment with impedance cardiography may be useful in Cushing’s disease patients in order to identify subclinical cardiovascular complications of chronic hypercortisolemia as potential therapeutic targets.


2013 ◽  
Vol 66 (11-12) ◽  
pp. 497-501 ◽  
Author(s):  
Marijana Matic ◽  
Jovana Jovanovic ◽  
Jovica Jovanovic ◽  
Nada Macvanin

Introduction. The aim of this research was to quantify the presence of occupational stressors and to analyze their effects on temporary and permanent working ability of workers with arterial hypertension. Material and Methods. The research included 817 workers. The study group consisted of 504 workers with arterial hypertension without other diseases or disorders, whereas the control group was composed of 313 healthy workers. Results. The study group showed a significantly higher level of total occupational stress index as well as of the stress index related to high job demands, conflicts at work place, underload and time limit (p<0.001) compared to the control group. A positive and statistically significant correlation between total occupational stress index and systolic and diastolic blood pressure was found in the study group. The total level of occupational stress over 40 led to a significant increase of systolic and diastolic blood pressure in persons with arterial hypertension. The analysis of temporary working inability determined a statistically significantly higher level of lost workdays per a worker in the study group compared to the controls (p<0.001). The average number of lost workdays per a worker in a year in the study group increased statistically significantly along with the occupational stress index values at their work place (p<0.001). In the study group the number of workers eligible for disability retirement over a period of one year was significantly higher compared to the controls. The number of workers eligible for disability retirement in the exposed group increased statistically significantly along with occupational stress index values at their work place. Conclusion. The results show that occupational stress is a significant factor in the development of arterial hypertension and reduction of work ability of exposed workers.


Author(s):  
Domenico Di Raimondo ◽  
Gaia Musiari ◽  
Alida Benfante ◽  
Salvatore Battaglia ◽  
Giuliana Rizzo ◽  
...  

Background: several studies report an increased risk for asthmatic subjects to develop arterial hypertension and the relationship between these two diseases, frequently co-existing, still has some unclear aspects. Methods: The BADA (blood pressure levels, clinical features and markers of subclinical cardiovascular damage of asthma patients) study is aimed to evaluate the prevalence of the cardiovascular comorbidities of asthma and their impact on the clinical outcome. The main exclusion criteria were the presence of other respiratory diseases, current smoking, any contraindication to ambulatory blood pressure monitoring (ABPM). Results: The overall percentage of asthmatics having also hypertension was 75% (30 patients) vs. 45% (18 patients) of the control group (p: 0.012). Reduced level of FEV1 (but not inhaled steroid therapy) was associated to newly-diagnosed hypertension (p: 0.0002), higher day SBP levels (p: 0.003), higher day DBP levels (p: 0.03), higher 24 h-SBP levels (p: 0.005) and higher 24h-DBP levels (p: 0.03). The regression analysis performed taking into account sex, age, diabetes, fasting glucose, and body mass index confirms the independent role played by asthma: odds ratio (OR): 3.66 (CI: 1.29–11.1). Conclusions: hypertension is highly prevalent in asthma; the use of ABPM has allowed the detection of a considerable number of unrecognized hypertensives.


2020 ◽  
Vol 100 (6) ◽  
pp. 108-113
Author(s):  
A.B. Miroshnikov ◽  
A.D. Formenov ◽  
A.B. Smolensky

Athletes of power sports, often appear to us as a model of a beautiful and healthy body, but the health of the cardiovascular system ofthese athletes has long falls under the gaze of cardiologists and sport physicians. Purpose of the study. A comparative analysis of the influence of a uniform and high-intensity aerobic exercise on blood pressure lowering power sports athletes with hypertension. Research Methods. The study involved 83 representatives of power sports (bodybuilding) with arterial hypertension. The average age of male athletes was 31.2 ± 4.5 years, and the body mass index was 32.4 ± 2.8 kg/m 2. To achieve this goal, the following methods were used: examination, interrogation, triple measurement of blood pressure, ergospirometry and methods of mathematical statistics. Athletes were randomized into three groups: interval training group (n = 33), uniform training (n = 30) and control group (n = 20). For 120 days (3 times a week), the athletes of the main groups performed various aerobic work programs, and the control group athletes trained according to their traditional strength protocol. Results. After 120 days of physical rehabilitation, a similar, significant decrease in systolic and diastolic blood pressure occurred in themain intervention groups. A decrease in blood pressure in the control group was not statistically significant. Conclusions. Despite the similar benefits in cardio-rehabilitation interval work required 38% less time, which can significantly affect adherence to a non-specific for this sport activity and screening of participant’s lengthy rehabilitation.


2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
N Ryumshina ◽  
A E Sukhareva ◽  
O V Mochula ◽  
T A Shelkovnikova ◽  
A S Maksimova ◽  
...  

Abstract Aim To value the possible relationship between the intensity of neoangiogenesis in the aortic wall in patients with resistant arterial hypertension and the subsequent development of ischemic cerebral disorders in them over a three-year follow-up. Materials and methods This study comprised 36 patients with resistant hypertension, in whom the renal denervation was carried out. MRI of the brain and also with contrast enhancement of the aorta and kidneys were examined. MRI studies included T2 and T1 spin-echo MRI, and also coronal slices, with suppression of the signal from adipose tissue (TR=150 ms, TE = 4 ms), before and in 12–15 minutes after contrast-enhanced. The diameter and thickness of the wall of the descending aorta were measured. Index of the enhancement of the aortic wall was calculated as the ratio of intensities of the wall after, and before contrast-enhanced. 9 according to MRI data - developed an acute ischemic stroke during this period, and 27 had no cerebral circulation disorders. The control group consisted of individuals without hypertension (n=12). Results After renal denervation, the systolic blood pressure significantly decreased in all patients for more than 15 mm Hg. In groups of patients with ischemic stroke, and without it, the diameter of the aortic lumen at the level above the renal arteries was 22,1±2,4 mm and 22,8±2,7 mm, respectively; the aortic wall thickness was 3,9±0,7 mm and 3,7±0,8 mm. In control subjects without hypertension, the wall thickness was less than 2,7 mm (on average 2,2±0,4 mm), with an aortic diameter of 21,3±0,9. As to the index of enhancement (as a marker of neoangiogenesis intensity) in the control group, in everybody, the IE was &lt;1,12. In patients with stroke within 3 years after renal denervation, IE = 2,12±0,31, and in patients without stroke IE = 1,66±0,19. The value of IE = 1,82 was the best for separating groups with and without stroke in the three years endpoint, as from the ROC analysis. Conclusion Contrast enhancement of the aortic wall in MRI is associated with the risk of brain ischemic stroke in patients with resistant arterial hypertension, even when blood pressure control is achieved by renal denervation. This makes it possible to predict the risk of stroke in these patients more reliably and encourages the inclusion of agents that reduce the activity of inflammation and pathological neoangiogenesis in the aortic wall, to the spectrum of antihypertensive therapy. FUNDunding Acknowledgement Type of funding sources: None. Brain MRI T2WI MRI of the kidneys and aorta, T1WI


10.12737/3316 ◽  
2014 ◽  
Vol 21 (1) ◽  
pp. 66-72 ◽  
Author(s):  
Белоусова ◽  
A. Belousova ◽  
Агасаров ◽  
Lev Agasarov

Due to the active professional activities of women aged 45-60, in the modern society, the after-care treatment of female patients with essential arterial hypertension (stages I-II , grades 1-2 ) under pressure of climacteric syndrome is of high social and economic importance. The specialists of medical rehabilitation are the problem of finding effective technologies of medical and non-medical series for improving the quality of life of women in this age group. This article presents the results of after-care treatment of women with essential arterial hypertension and mild or moderate climacteric syndrome (92 females aged 50±4.5) by means of the use of standard hypotensive pharmaceuticals (Candesartan, Bisoprolol, and Hydrochlorothiazide), non-hormonal pharmaceuticals (Klimadynon Uno), and spectral phototherapy as a physiotherapy approach. Such treatment resulted in reliable stabilization of blood pressure, vegetative functions, responsiveness, anxiety, encephalitic circulatory dynamics according to the REG data, and WAN indicators. The average clinical response of the control group amounts to 81.4 %, while that of the experimental group makes up 65.5 %. The key results are sustainable blood pressure stabilization, improved overall health, decreased frequency and severity of the climacteric syndrome along with stabilized vegetative functions, improved encephalitic circulatory dynamics, and psycho-emotional state.


Nutrients ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 274 ◽  
Author(s):  
Nicola Di Daniele ◽  
Giulia Marrone ◽  
Manuela Di Lauro ◽  
Francesca Di Daniele ◽  
Daniela Palazzetti ◽  
...  

The most common manifestation of cardiovascular (CV) diseases is the presence of arterial hypertension (AH), which impacts on endothelial dysfunction. CV risk is associated with high values of systolic and diastolic blood pressure and depends on the presence of risk factors, both modifiable and not modifiable, such as overweight, obesity, physical exercise, smoking, age, family history, and gender. The main target organs affected by AH are the heart, brain, vessels, kidneys, and eye retina. AH onset can be counteracted or delayed by adopting a proper diet, characterized by a low saturated fat and sodium intake, a high fruit and vegetable intake, a moderate alcohol consumption, and achieving and maintaining over time the ideal body weight. In this review, we analyzed how a new nutritional approach, named caloric restriction diet (CRD), can provide a significant reduction in blood pressure values and an improvement of the endothelial dysfunction. In fact, CRD is able to counteract aging and delay the onset of CV and neurodegenerative diseases through the reduction of body fat mass, systolic and diastolic values, free radicals production, and oxidative stress. Currently, there are few studies on CRD effects in the long term, and it would be advisable to perform observational studies with longer follow-up.


2009 ◽  
Vol 6 (4) ◽  
pp. 59-63
Author(s):  
Il'ya Mikhaylovich Davidovich ◽  
Oleg Vladimirovich Afonaskov ◽  
Yuliya Konstantinovna Staroverova

Aim: to evaluate memory, attention and thinking functions indices in young hired military officers depending on their 24-hours blood pressure profiles. Materials and methods. The study was made in 49 patients with stage 1-2 arterial hypertension, aged 39,3±0,8, who did not take hypotensive medicines or took them occasionally. 24-hours blood pressure monitoring was performed with assessment of cognitive functions (memory, attention) depending on the stage, degree and duration of the disease. The control group included 12 men with no signs of arterial hypertension. Results. Comparing with the controls the memory, attention and thinking indices in hypertonic patients were found to be lower .even in those who had the first degree of hypertension and duration of the disease less than 5 years. The hypertonic patients showed lowering of attention and semantic memory scopes irrespective of duration of the disease. There was a negative correlation between monitored blood pressure data and memory, attention and thinking indices. Conclusions. Light cognitive dysfunctions can be found in young hired military officers with initial arterial hypertension but they are more typical for stage 2 of the disease


Author(s):  
Vadim P. Mikhin ◽  
Evgenia V. Gavrilyuk ◽  
Irina V. Evsegneeva

The purpose of the study was to assess the parameters of innate immunity in patients with essential arterial hypertension and to establish a relationship with the effectiveness of antihypertensive pharmacotherapy. Materials and methods. The study included 48 patients with essential arterial hypertension stage II, arterial hypertension 2 degree and hypertrophy of the left ventricular myocardium, which were divided into 2 groups: the first group (25 patients) - these are patients whose blood pressure reached the target values, and the second group (23 patients) are patients whose blood pressure did not reach the target values against the background of antihypertensive therapy (perindopril - 5 mg/day and amlodipine - 5 mg/day) (group 2). Indicators of 18 healthy donors were used as a comparison group (control group). Results. In patients with essential arterial hypertension of group 1, compared with the control group, the concentration of IL-1α, IL-6, IL-8, IL-10, IL-1 receptor antagonist, IL-2, C4- and C5a-components of the complement system and factor H is significantly higher and the level of C3 is lower-component of the complement system. In patients with essential arterial hypertension of group 2, more pronounced changes in the cytokine link of the immunity and the complement system were established before the start of antihypertensive therapy. After the antihypertensive therapy in patients with essential arterial hypertension of the 1st group in the blood plasma, the concentration of TNF, IL-1α, IL-8, IL-10, IL-1 receptor antagonist significantly decreased, but not to the values of the control group, and in patients of the 2nd group, the effectiveness of antihypertensive therapy in correcting parameters innate immunity was found to be less effective. Conclusion. Revealing the participation of innate immunity indicators in the formation of arterial hypertension opens up new possibilities for the pathogenetic therapy of this disease and developing measures to prevent or level the damage to target organs.


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