scholarly journals Rapid increases in the steady-state concentration of reactive oxygen species in the lungs and heart after particulate air pollution inhalation.

2002 ◽  
Vol 110 (8) ◽  
pp. 749-755 ◽  
Author(s):  
Sonia A Gurgueira ◽  
Joy Lawrence ◽  
Brent Coull ◽  
G G Krishna Murthy ◽  
Beatriz González-Flecha
Keyword(s):  
Reactive Oxygen Species ◽  
Air Pollution ◽  
Steady State ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Steady State Concentration ◽  
Particulate Air Pollution ◽  
State Concentration

Effect of oxidative stress during imbibition of soybean embryonic axes

1994 ◽  
Vol 102 ◽  
pp. 279-286 ◽  
Author(s):  
Susana Puntarulo
Keyword(s):  
Oxidative Stress ◽  
Steady State ◽  
External Medium ◽  
Tocopherol Content ◽  
Active Species ◽  
Oxygen Species ◽  
Steady State Concentration ◽  
Embryonic Axes ◽  
State Concentration

SynopsisBoth respiration and generation by soybean embryonic axes showed a sharp increase upon germination, leading to a significant increase in the steady-state concentration of and H2O2 after 6 h of imbibition. An assay was developed to assess in vivo generation of reactive oxygen species, based upon DCFH-DA oxidation. Fluorescence of the external medium was dependent on reaction time and axes number and was inhibited by catalase.α-Tocopherol content declined significantly after 24 h of incubation, as compared to the content at the onset of germination. Incubation in the presence of redox cycling agent paraquat (4 mM) for 24 h increased α-tocopherol content to 1.9±0.2 nmol per axis from 1.0 ± 0.1 nmol per axis in the absence of paraquat. Supplementation of the incubation medium with 500 μM Fe-EDTA increased α-tocopherol content to 1.8±0.1 nmol/axis and DCFH-DA oxidation by two-fold.The data presented here showed that active metabolism at the onset of germination increased steady-state concentration of oxygen active species and suggest that cellular content of α-tocopherol is physiologically adjusted as a response to conditions of oxidative stress.

scholarly journals Antioxidant inhibition of steady-state reactive oxygen species and cell growth in neuroblastoma

Surgery ◽  
2015 ◽  
Vol 158 (3) ◽  
pp. 827-836 ◽  
Author(s):  
Yueming Zhu ◽  
Pritha Paul ◽  
Sora Lee ◽  
Brian T. Craig ◽  
Eric J. Rellinger ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Steady State ◽  
Cell Growth ◽  
Reactive Oxygen ◽  
Oxygen Species

Effect of nanosilver surfaces on peptide reactivity towards reactive oxygen species

Nanoscale ◽  
2018 ◽  
Vol 10 (34) ◽  
pp. 15911-15917 ◽  
Author(s):  
Erik Jacques ◽  
Manuel Ahumada ◽  
Brianna Rector ◽  
Goonay Yousefalizadeh ◽  
Constanza Galaz-Araya ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Molecular Dynamics ◽  
Steady State ◽  
Free Radical ◽  
Ultrafast Spectroscopy ◽  
Reactive Oxygen ◽  
Free Radical Oxidation ◽  
Oxygen Species ◽  
Radical Oxidation

Free radical oxidation of CLP-Trp peptides@AgNPs was studied using steady state & ultrafast spectroscopy and molecular dynamics.

scholarly journals Variations in Reactive Oxygen Species Generation by Urban Airborne Particulate Matter in Lung Epithelial Cells—Impact of Inorganic Fraction

2020 ◽  
Vol 8 ◽  
Author(s):  
Olga Mazuryk ◽  
Grazyna Stochel ◽  
Małgorzata Brindell
Keyword(s):  
Reactive Oxygen Species ◽  
Air Pollution ◽  
Particulate Matter ◽  
Epithelial Cells ◽  
A549 Cells ◽  
Reactive Oxygen ◽  
Airborne Particulate Matter ◽  
Oxygen Species ◽  
Airborne Particulate ◽  
Inorganic Fraction

Air pollution is associated with numerous negative effects on human health. The toxicity of organic components of air pollution is well-recognized, while the impact of their inorganic counterparts in the overall toxicity is still a matter of various discussions. The influence of airborne particulate matter (PM) and their inorganic components on biological function of human alveolar-like epithelial cells (A549) was investigated in vitro. A novel treatment protocol based on covering culture plates with PM allowed increasing the studied pollutant concentrations and prolonging their incubation time without cell exposure on physical suffocation and mechanical disturbance. PM decreased the viability of A549 cells and disrupted their mitochondrial membrane potential and calcium homeostasis. For the first time, the difference in the reactive oxygen species (ROS) profiles generated by organic and inorganic counterparts of PM was shown. Singlet oxygen generation was observed only after treatment of cells with inorganic fraction of PM, while hydrogen peroxide, hydroxyl radical, and superoxide anion radical were induced after exposure of A549 cells to both PM and their inorganic fraction.

scholarly journals Within-city Variation in Reactive Oxygen Species from Fine Particle Air Pollution and COVID-19

2021 ◽  
Author(s):  
David M Stieb ◽  
Greg J Evans ◽  
Teresa M. To ◽  
Pascale S.J. Lakey ◽  
Manabu Shiraiwa ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Air Pollution ◽  
Fine Particle ◽  
Reactive Oxygen ◽  
Oxygen Species
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