Severe Complication of Thiopurine Treatment in a Young Woman with Crohn’s Disease
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Case Description: TA 28-year old woman receiving thiopurine treatment for Crohn’s disease presented with a systemic primo cytomegalovirus (CMV) infection affecting the gut (colitis), liver (hepatitis), lungs (pneumonitis) and eyes (retinitis). Secondary to this systemic infection, she developed splenomegaly, pancytopenia and lymphadenopathy. Anti-viral treatment resulted in complete resolution of clinical, biochemical and radiological abnormalities within 6 weeks. Conclusion: Early recognition is crucial since CMV infection in a patient receiving thiopurine treatment may result in serious complications.
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2018 ◽
Vol 56
(03)
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pp. 259-263
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2015 ◽
Vol 9
(12)
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pp. 1169-1173
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2010 ◽
Vol 55
(5)
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pp. 1498-1499
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2020 ◽
Vol 115
(1)
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pp. S1800-S1800