Sexual difficulties in patients with inflammatory bowel disease (IBD): results of a 2-year study

2020 ◽  
Vol 18 (6) ◽  
pp. 34-42
Author(s):  
Dean A Tripp ◽  
Madelaine Gierc ◽  
Phylicia Verrault ◽  
Katherine Fretz ◽  
Mark Ropeleski ◽  
...  

Background: Sexual difficulties are common in individuals with inflammatory bowel disease (IBD). Aims: This study aimed to document sexual difficulties in IBD; to investigate longitudinal patterns in these difficulties; and to identify biopsychosocial factors that may serve as predictors of these difficulties. Methods: A longitudinal study was conducted, with IBD outpatients completing three questionnaires across 2 years. Items assessed biopsychosocial variables (e.g., age, PHQ-9, Multidimensional Scale of Perceived Social Support) and sexual difficulties (Golombok-Rust Inventory of Sexual Satisfaction). Findings: Patients reported a moderate level of sexual difficulties, with 17.5–74.5% exceeding the threshold of clinical significance across domains. No significant changes in sexual difficulties occurred across the study period. Biopsychosocial factors accounted for up to 25.2% of the variance in sexual difficulties, with age, depressive symptoms, pain-related disability, perceived social support, and optimism associated with these difficulties in the hypothesised directions. Conclusions: Patients reported significant sexual difficulties in several domains, with a high degree of stability over time. Biopsychosocial factors were associated with reported sexual difficulties, particularly older age and lower perceived social support. These factors are suggested as targets for intervention research.

2009 ◽  
Vol 104 ◽  
pp. S439
Author(s):  
Sharon Jedel ◽  
Sunana Sohi ◽  
Amita Thakkar ◽  
Mary Morrissey Kwasny ◽  
Ali Keshavarzian

2010 ◽  
Vol 138 (5) ◽  
pp. S-522
Author(s):  
Florian Rieder ◽  
Stephan Schleder ◽  
Alexandra Wolf ◽  
Anja Schirbel ◽  
Andre Franke ◽  
...  

Author(s):  
James D Lewis ◽  
Raymond K Cross ◽  
Millie Long ◽  
Siddharth Singh ◽  
Hans Herfarth ◽  
...  

Lay Summary Dysplasia surveillance practice varies widely among high-volume inflammatory bowel disease providers. We surveyed high-volume inflammatory bowel disease providers about practice patterns to detect dysplasia. Regular use of dye-based chromoendoscopy was reported by 20%, virtual chromoendoscopy by 27%, and random biopsies by 58%.


2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 10576-10576
Author(s):  
Colin Wikholm ◽  
Shiva Shankar Vangimalla ◽  
Ehab Abaza ◽  
Akram Ahmad ◽  
Ioannis Pothoulakis ◽  
...  

10576 Background: Inflammatory bowel disease (IBD) and use of immunosuppressive therapy in IBD is linked with increased risk of leukemia. We studied the NIS database from 2003-2017 to analyze trends in any type of leukemia in IBD hospitalizations over time and examined the role of age, sex, and race. Methods: We analyzed NIS data of all adult hospitalizations for ulcerative colitis (UC) or Crohn’s disease (CD) with any type of leukemia as a primary or secondary diagnosis using validated ICD 9/10 codes. Age, sex, and racial demographics were collected. Trend analysis of leukemia was performed with Cochran-Armitage and Jonckheere-Terpstra tests. Results: Overall Trends: From 2003-2017, a total of 11,385 of 2,235,413 (0.51%) CD hospitalizations and 8,105 of 1,324,746 (0.61%) UC hospitalizations contained diagnosis of leukemia. An increase in leukemia was seen in both CD and UC group from 0.24% to 0.79% (pTrend < 0.0001) and 0.28% to 0.81% (pTrend < 0.0001) respectively. Sex: In both UC and CD patients, leukemia diagnoses were predominantly male in 2003 but approximated a near 1:1 ratio by 2017 (Table). In CD, the proportion of female (FEM) leukemia diagnoses grew from 31.33% to 45.05% from 2003 to 2017 (pTrend = 0.1898). In UC, the proportion of female leukemia diagnoses grew from 27.49% to 45.79% from 2003 to 2017 (pTrend = 0.0030). Age: Leukemia was more common with increasing age, with no significant changes in proportion of cases between age groups over time (pTrend >.05). Ethnicity: White patients composed 87.80% and 84.24% of leukemia diagnoses in CD and UC, respectively. In CD, an increasing proportion of leukemia diagnoses occurred in black (BK) patients, and a decreasing proportion occurred in white patients (pTrends <.0001; Table 1) during the study time. No trends in race were observed in the UC group (pTrend = 0.4229). Conclusions: Our study showed an increased prevalence of leukemia in CD and UC hospitalizations from 2003-2017 which may be related to increasing use of immunosuppressants such as anti-TNF medications. In both CD and UC, leukemia was male-predominant, but increasingly female by 2017. Rate of leukemia diagnosis increased with age. In the CD group but not the UC group, leukemia was increasingly prevalent in black patients.[Table: see text]


2013 ◽  
Vol 144 (5) ◽  
pp. S-765-S-766
Author(s):  
Edgar Wills ◽  
Daisy Jonkers ◽  
Paul Savelkoul ◽  
Marie J. Pierik ◽  
Ad Masclee ◽  
...  

2020 ◽  
Vol 11 (9) ◽  
pp. e00227
Author(s):  
Mafalda Santiago ◽  
Fernando Magro ◽  
Luís Correia ◽  
Francisco Portela ◽  
Paula Ministro ◽  
...  

2016 ◽  
Vol 52 (3) ◽  
pp. 344-350 ◽  
Author(s):  
Karin Amcoff ◽  
Mats Stridsberg ◽  
Maria Lampinen ◽  
Anders Magnuson ◽  
Marie Carlson ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Christopher Moore ◽  
Shriram Jakate ◽  
Ali Keshavarzian

Inflammatory bowel disease (IBD) comprises the principal subtypes Crohn’s disease (CD) and ulcerative colitis (UC), with a fraction remaining as IBD unclassified (IBDU). Given the complexity of IBD manifestations in a patient over time and our increasing understanding of IBD biology, a modification in subtype diagnosis can also occur. Herein is a case of a 27-year-old female with well-controlled and long-standing pan-UC, who developed Crohn’s-like esophagogastroduodenitis. The difficulty in classifying IBD into a single traditional subtype, and the debated presentation of a coexistent IBD will be discussed.


2012 ◽  
Vol 142 (5) ◽  
pp. S-387
Author(s):  
Jonathan Wong ◽  
Richard N. Fedorak ◽  
Karen Wong ◽  
Karen I. Kroeker

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