scholarly journals Penile calciphylaxis: a conservative approach

2020 ◽  
Vol 102 (2) ◽  
pp. e36-e38 ◽  
Author(s):  
O El-Taji ◽  
J Bondad ◽  
S Faruqui ◽  
J Bycroft
Keyword(s):  
Renal Failure ◽  
End Stage Renal Disease ◽  
Multidisciplinary Approach ◽  
Renal Dialysis ◽  
Conservative Approach ◽  
End Stage Renal Failure ◽  
Calcific Uremic Arteriolopathy ◽  
Individual Entity ◽  
Stage Renal Disease ◽  
End Stage

Penile calciphylaxis or calcific uremic arteriolopathy is a rare urological condition often associated with patients undergoing renal dialysis for end-stage renal disease. The majority of cases are associated with systemic calciphylaxis. The pathophysiology, diagnosis and management of penile calciphylaxis as an individual entity has brought little attention. The rates of comorbidity and mortality of these patients are often particularly high. Early diagnosis and a multidisciplinary approach are therefore essential. We report a case of penile calciphylaxis in a 59-year-old man with end-stage renal failure on haemodialysis who was successfully managed conservatively.

scholarly journals Oral Anticoagulant Therapy in Patients Receiving Haemodialysis: Is It Time to Abandon It?

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Marek Saracyn ◽  
Dorota Brodowska-Kania ◽  
Stanisław Niemczyk
Keyword(s):  
Atrial Fibrillation ◽  
Renal Failure ◽  
Venous Thromboembolism ◽  
End Stage Renal Disease ◽  
Oral Anticoagulant ◽  
Oral Anticoagulant Therapy ◽  
End Stage Renal Failure ◽  
The Moment ◽  
Stage Renal Disease ◽  
End Stage

Oral anticoagulant (OAC) therapy in haemodialysis patients causes a great deal of controversy. This is because a number of pro- and anticoagulant factors play an important role in end-stage renal failure due to the nature of the disease itself. In these conditions, the pharmacokinetic and pharmacodynamic properties of the OACs used change as well. In the case of the treatment of venous thromboembolism, the only remaining option is OAC treatment according to regimens used for the general population. Prevention of HD vascular access thrombosis with the use of OACs is not very effective and can be dangerous. However, OAC treatment in patients with atrial fibrillation in dialysis population may be associated with an increase in the incidence of stroke and mortality. Doubts should be dispelled by prospective, randomised studies; at the moment, there is no justification for routine use of OACs in the above-mentioned indications. In selected cases of OAC therapy in this group of patients, it is absolutely necessary to control and monitor the applied treatment thoroughly. Indications for the use of OACs in patients with end-stage renal disease, including haemodialysis patients, should be currently limited.

Issues Related to the Care of Critically Ill Patients with End Stage Renal Failure

1992 ◽  
Vol 3 (3) ◽  
pp. 585-596
Author(s):  
Christy A. Price
Keyword(s):  
Renal Failure ◽  
Intensive Care ◽  
Critically Ill ◽  
End Stage Renal Disease ◽  
Treatment Options ◽  
Nursing Interventions ◽  
End Stage Renal Failure ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

End stage renal disease (ESRD) affects every aspect of an individual’s lifestyle. Pharmacologic, dietary, and treatment options and other organ involvement become daily realities for ESRD patients. When ESRD patients are admitted to intensive care units, these realities become concerns for the nurses. This article addresses the considerations that must be included in the nursing interventions for the critically ill ESRD patients

The Effect of Somatostatin on the Hormonal Abnormalities of End Stage Renal Disease

1981 ◽  
Vol 9 (1) ◽  
pp. 1-5
Author(s):  
Thomas G Murray ◽  
Carol Eisen ◽  
Morris Grabie ◽  
Ellen Buerklin ◽  
Barry R Walker ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Renal Failure ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Control Period ◽  
Thyroid Stimulating Hormone ◽  
Dialysis Patients ◽  
End Stage Renal Failure ◽  
Stage Renal Disease ◽  
End Stage

Patients with end stage renal disease who are maintained on haemodialysis have elevated levels of many hormones, some of which may play a role in the pathogenesis of the complications of uraemia. The infusion of synthetic somatostatin reduces the circulating level of many of these same hormones in patients with normal renal function. If the elevated hormone levels in dialysis patients could be similarly lowered, study of the pathogenitic significance of the various hormonal abnormalities would be facilitated. With this in mind, the effect of synthetic somatostatin on the circulating level of growth hormone, glucagon, insulin, gastrin, parathyroid hormone, and thyroid stimulating hormone in dialysis patients was investigated. In pilot protocol, a dose of 2 mg of somatostatin infused over 24, 18, or 12 hours (two patients each) was found to have no effect on any hormonal level. Infusion of 2 mg of somatostatin over 4 hours, however, was associated with consistent fall in the level of growth hormone (13.6 ± 6.2 to 6.53 ± 2.9, p = 0.15) and glucagon (595.0 ± 73 to 441 ± 28, p < 0.05) in each of four patients. The percentage change in the level of growth hormone and glucagon during the 4-hour somatostatin infusion was significantly different from the change occurring during a 4-hour timed control period (growth hormone —45 ± 18% vs +9 ± 7%, [p < 0.05]), (glucagon −27% ± 2% vs + 8 ± 2%, [p < 0.01]). There was no change in the level of any other hormone during the 4-hour infusion. No significant adverse effects were seen. This study suggests that the intravenous infusion of somatostatin can, at least on an acute basis, lower the level of growth hormone and glucagon in patients with end stage renal failure; and, therefore, it may be useful in further study and possibly the treatment of the hormonal abnormalities of end stage renal disease.

scholarly journals HARAPAN PADA PENYAKIT GINJAL KRONIS TAHAP AKHIR (PGKTA) : SYSTEMATIC REVIEW

2019 ◽  
Vol 2 (2) ◽  
pp. 41
Author(s):  
Nining Puji Astuti
Keyword(s):  
Systematic Review ◽  
Renal Failure ◽  
Renal Disease ◽  
Full Text ◽  
End Stage Renal Disease ◽  
End Stage Renal Failure ◽  
Herth Hope Index ◽  
Trait Hope ◽  
Stage Renal Disease ◽  
End Stage

Latar belakang:. Harapan merupakan faktor prediktor independen yang berhubungan langsung dengan kualitas hidup PGKTA. Harapan memiliki peran penting untuk meningkatkan motivasi, koping, kemauan menjalani pengobatan dan outcome positif PGKTA.Tujuan: Tujuan dari sistematic review ini adalah untuk mengidentifikasi konsep harapan berdasarkan definisi dan instrumen yang dapat digunakan untuk mengukur harapan PGKTA, mengidentifikasi faktor yang mempengaruhi harapan PGKTA.Metode: Metode pencarian melalui PUBMED dan Google Schoolar dengan kata kunci “hope, End Stage Renal Disease, End Stage Renal Failure, Hemodialysis”. Hanya jurnal dalam Bahasa Inggris, full text, dipublikasikan tahun 2000-2019 dan menggunakan harapan sebagai tema utama dalam pembahasan yang digunakan dalam pembuatan sistematik review ini.Hasil : Harapan di definisikan sebagai kekuatan dalam diri individu yang membantu pasien keluar dari zona sakitnya dan meningkatkan derajat kesehatannya. Alat ukur yang dapat dipakai antara lain Herth Hope Index, The Trait Hope Scale, Adult Hope Scale, Miller Hope Scale, Basic Hope Inventory.Kesimpulan: Perlu kajian lebih dalam mengenai faktor dominan yang mempengaruhi harapan untuk membantu penentuan asuhan keperawatan yang tepat terkait harapan.

P97 An uncommon reason of end stage renal disease: 3 cases with joubert syndrome and renal failure

2017 ◽  
Author(s):  
Aysun Karabay Bayazit ◽  
Bahriye Atmi&scedil; ◽  
Engin Melek ◽  
Abdulsamet Ala ◽  
Merve Sapmaz ◽  
...  
Keyword(s):  
Renal Failure ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Joubert Syndrome ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Dynamic changes in calcium and phosphate plasma concentrations in the patients on peritoneal dialysis

2006 ◽  
Vol 63 (1) ◽  
pp. 27-30
Author(s):  
Natasa Jovanovic ◽  
Mirjana Lausevic ◽  
Biljana Stojimirovic
Keyword(s):  
Vitamin D ◽  
Renal Failure ◽  
Peritoneal Dialysis ◽  
End Stage Renal Disease ◽  
Calcium Concentration ◽  
Phosphate Binders ◽  
Active Vitamin ◽  
Active Vitamin D ◽  
Stage Renal Disease ◽  
End Stage

Background/Aim. The disturbances of active forms of vitamin D synthesis and disturbances in calcium and posphate metabolism develop early in chronic renal failure, when creatinine clearance is about 30 ml/min. Chronic hemodialysis and peritoneal dialysis only partially correct the biochemical environment of patients on chronic renal replacement therapy because of end-stage renal disease. These dialysis modalities can?t significantly affect the endocrine disturbances of chronic renal failure and they have minimal modulatory effect. The management of disturbed calcium (Ca) and phosphate (P) metabolism and the maintainance of Ca ? P product below 4.4 mmol/l thanks to the use of dialysate solutions with the appropriate calcium concentration and the careful dosage of phosphate binders, calcium and active vitamin D metabolits, are extremely important for the prevention of renal osteodystrophy, secondary hyperparathyroidism as well as low-bone turnover disease. The aim of the study was to analyze the plasma levels of calcium, phosphate, albumin, alkaline phosphatase and parathormon (PTH) in 58 patients who were treated with continuous ambulatory peritoneal dialysis (CAPD) from March to August 2003. The use of phosphate binders and the substitution with active vitamin D metabolits were also analyzed. Methods. We examined 58 patients, 30 males and 28 female, mean-age 52 years (range, 26-78 years), affected by end-stage renal disease of the different leading cause. The average time on peritoneal dialysis program was 20 months (2-66 months). Most of the patients were treated by CAPD, while only few of them performed automatic, cyclic or intermittent peritoneal dialysis. Most of the patients used a dialysate with 1.75 mmol/l calcium concentration. Results. The study showed that our patients on chronic CAPD program during several months had normal calcemia, phosphatemia and the level of alkaline phosphatase, and that they had Ca ? P product in the recommended range. PTH serum level ranged from 16 to 490 pg/l in our patients. Conclusion. The study showed that a balanced diet and a correct dosage of phosphate binders, as well as a careful substitution with active vitamin D metabolits render a good control of calcium and phosphate serum balance, as well as an effective prevention of renal osteodystrophy development in the patients on chronic peritoneal dialysis treatment.

scholarly journals Acute Intradialytic Complications in End Stage Renal Disease on Maintenance Hemodialysis

2012 ◽  
Vol 52 (187) ◽  
Author(s):  
R K Agrawal ◽  
S Khakurel ◽  
R Hada ◽  
D Shrestha ◽  
A Baral
Keyword(s):  
Renal Failure ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Maintenance Hemodialysis ◽  
Care Hospital ◽  
Cross Sectional ◽  
Stage Renal Disease ◽  
End Stage

Introduction: Hemodialysis is the preferred method of treatment for Nepalese patients with End Stage Renal Disease. Despite the technological advances and better understanding of physiology associated with hemodialysis, a number of complications are known to be associated with hemodialysis. This study was undertaken to study the frequency of acute intradialytic complications in patients undergoing hemodialysis. Methods: A cross-sectional study was conducted at Nephrology unit of a tertiary care hospital from 15 June, 2007 to 15 December, 2007. A total of 28 patients were included in the study. Patients with acute renal failure and acute on chronic renal failure were excluded from the study. Results: Total sessions of hemodialysis during the period were 1455. Hypotensive episode were 66 (4.5%) and was the commonest complication and followed by hypertensive episodes were 58 (3.8%). Other problems encountered were transfusion reactions were 23 episodes (1.5%), rigors not related to transfusions were 13 episodes (0.8%), nausea/vomiting were 20 episodes (1.4%), muscle cramps were 12 episodes (0.8%), hypoglycemia were 6 episodes 5(0.4%). Conclusions: The frequency of intradialytic complications is low and many of them are not life threatening. Keywords: complications; end stage renal disease; hemodialysis; hypertension; hypotension.

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