Wide field mapping of cell-specific contributions to brain function

2020 ◽  
Author(s):  
Joonhyuk Lee ◽  
Annie R. Bice ◽  
Adam Q. Bauer
Keyword(s):  
Brain Function ◽  
Wide Field ◽  
Field Mapping

scholarly journals EVN-Merlin Observations of the Remarkable Lens System: 2016+112

1996 ◽  
Vol 173 ◽  
pp. 339-340
Author(s):  
M.A. Garrett ◽  
S. Nair ◽  
D. Walsh ◽  
R.W. Porcas ◽  
A.R. Patnaik
Keyword(s):  
Field Of View ◽  
Wide Field ◽  
Common Elements ◽  
Lens System ◽  
Field Mapping ◽  
Mapping Techniques

2016+112 was observed simultaneously with the European VLBI Network (EVN) and MERLIN arrays during the May 1993 joint EVN-MERLIN session at λ18 cm. Common elements to both arrays included the Jodrell Bank 76-m Lovell and 32-m Cambridge telescopes. In order to simultaneously map the entire 4 arcsec2 field of view, various wide-field mapping techniques were employed (see Garrett et al. 1994b).

scholarly journals Simultaneous mesoscopic Ca2+ imaging and fMRI: Neuroimaging spanning spatiotemporal scales

2018 ◽  
Author(s):  
Evelyn MR Lake ◽  
Xinxin Ge ◽  
Xilin Shen ◽  
Peter Herman ◽  
Fahmeed Hyder ◽  
...  
Keyword(s):  
Brain Function ◽  
Brain Activity ◽  
Blood Oxygen Level Dependent ◽  
Optical Measurements ◽  
Wide Field ◽  
Blood Oxygen Level ◽  
Neural Basis ◽  
Novel Approach ◽  
Transgenic Murine Model ◽  
Spatiotemporal Scales

ABSTRACTTo achieve a more comprehensive understanding of brain function requires simultaneous measurement of activity across a range of spatiotemporal scales. However, the appropriate tools to perform such studies are largely unavailable. Here, we present a novel approach for concurrent wide-field optical and functional magnetic resonance imaging (fMRI). By merging these two modalities, we are for the first time able to simultaneously acquire whole-brain blood-oxygen-level-dependent and whole-cortex calcium-sensitive fluorescent measures of brain activity. We describe the developments that allow us to combine these modalities without compromising the fidelity of either technique. In a transgenic murine model, we examine correspondences between activity measured using these modalities and identify unique and complementary features of each. Our approach links cell-type specific optical measurements of neural activity to the most widely used method for assessing human brain function. These data and approach directly establish the neural basis for the macroscopic connectivity patterns observed with fMRI.

Wide field mapping of first-order optical inhomogeneities

2004 ◽  
Vol 6 (6) ◽  
pp. 597-603 ◽  
Author(s):  
C Razzetti ◽  
A Ponzoni ◽  
S Davoli ◽  
C Paorici
Keyword(s):  
Wide Field ◽  
Field Mapping ◽  
First Order

scholarly journals Opto-E-Dura: a Soft, Stretchable ECoG Array for Multimodal, Multi-scale Neuroscience

2020 ◽  
Author(s):  
Aline F. Renz ◽  
Jihyun Lee ◽  
Klas Tybrandt ◽  
Maciej Brzezinski ◽  
Dayra A. Lorenzo ◽  
...  
Keyword(s):  
Brain Function ◽  
Large Scale ◽  
Spatial Scales ◽  
Biological Tissues ◽  
Great Promise ◽  
Wide Field ◽  
Electrode Arrays ◽  
Spatial And Temporal Scales ◽  
Multi Scale ◽  
The Brain

AbstractSoft, stretchable materials hold great promise for the fabrication of biomedical devices due to their capacity to integrate gracefully with and conform to biological tissues. Conformal devices are of particular interest in the development of brain interfaces where rigid structures can lead to tissue damage and loss of signal quality over the lifetime of the implant. Interfaces to study brain function and dysfunction increasingly require multimodal access in order to facilitate measurement of diverse physiological signals that span the disparate temporal and spatial scales of brain dynamics. Here we present the Opto-e-Dura, a soft, stretchable, 16-channel electrocorticography array that is optically transparent. We demonstrate its compatibility with diverse optical and electrical readouts enabling multimodal studies that bridge spatial and temporal scales. The device is chronically stable for weeks, compatible with wide-field and 2-photon calcium imaging and permits the repeated insertion of penetrating multi-electrode arrays. As the variety of sensors and effectors realizable on soft, stretchable substrates expands, similar devices that provide large-scale, multimodal access to the brain will continue to improve fundamental understanding of brain function.

scholarly journals Wide Field Mapping of 5C12

1991 ◽  
Vol 131 ◽  
pp. 253-256
Author(s):  
J. E. Okopi ◽  
L. B. Bååth
Keyword(s):  
Fourier Transform ◽  
Basic Assumption ◽  
Mapping Technique ◽  
Wide Field ◽  
Two Dimensional ◽  
Data Set ◽  
Field Mapping ◽  
Sky Brightness

AbstractThe existing method of producing radio maps from interferometric data set is based on the assumption that there is a two dimensional fourier transform relationship between the sky brightness and the measured visibility. In mapping of a very wide field, this basic assumption breaks down due to various practical problems, e.g. bandwidth smearing. We present a wide-field mapping technique which is aimed at resolving some of these problems. This technique has been successfully applied to our MERLIN observations of the 5C12 region covering an area of 1800”×l800”.

scholarly journals The use of beam-sets in the Analysis of wide-field maps from the CLFST

1991 ◽  
Vol 131 ◽  
pp. 180-183
Author(s):  
Em Waldram
Keyword(s):  
Low Frequency ◽  
Chromatic Aberration ◽  
Wide Field ◽  
Frequency Synthesis ◽  
Beam Shape ◽  
Mapping Problem ◽  
Field Mapping

AbstractThe Cambridge Low Frequency Synthesis Telescope (CLFST) has baselines which are offset from the E-W direction by about 3°. The wide-field mapping problem has been overcome by the use of beam-sets, or artificial maps consisting of grids of synthesized beams, which incorporate the effects of both the geometric and chromatic aberration. By appropriate interpolation we can find a good approximation to the beam-shape at any point on a map.

Contour Map Point Distribution and Surgeon Experience Level Affect Accuracy of Surgical Navigation in a Pilot Study

2021 ◽  
pp. 000348942110059
Author(s):  
Jason Talmadge ◽  
Zi Yang Jiang ◽  
Denna A. Zebda ◽  
William C. Yao ◽  
Amber U. Luong ◽  
...  
Keyword(s):  
Surgical Navigation ◽  
Wide Field ◽  
Contour Map ◽  
Point Distribution ◽  
Field Mapping ◽  
Contour Maps ◽  
Experienced Surgeon ◽  
Surgeon Experience ◽  
Resident Surgeon ◽  
The Impact

Background: Reliable use of surgical navigation depends upon the registration process. The gold standard is paired-point registration with bone-anchored fiducials, but contour-map registration is more practical. Surgeons may employ variable contour maps and less experienced team members often perform this critical step. The impact of these practices on target registration error (TRE) is not well-studied. Methods: A dry lab set-up consisting of a navigation system (Fusion ENT, Medtronic, Jacksonville, FL) and a sinus phantom with 2 mm radiopaque spheres in the sphenoid and ethmoid regions was developed. A CT (0.625 mm slice thickness) was obtained. Registration was performed with a contour-based protocol. Accuracy was determined using the software’s distance measurement tool. Registration was performed with narrow-field (NF; forehead points medial to the mid-pupillary line) and wide field (WF; entire forehead) contour maps. An experienced rhinologist and a resident surgeon performed each registration in triplicate and TRE at the sphenoid and ethmoid markers was measured in triplicate. Results: WF mapping had a lower TRE than NF (1.09 mm [95% Confidence Interval (CI) 0.96-1.22] vs 1.68 mm [95% CI 1.50-1.86]). The experienced surgeon had a lower TRE compared to the resident (1.21 mm [95% CI 1.08-1.34] vs 1.54 mm [95% CI 1.35-1.74]). Conclusions: In this navigation model, wide field mapping offers better accuracy than narrow-field mapping, and an experienced surgeon seemed to achieve better accuracy than a resident surgeon. These observations have potential implications for the use of this technology in the operating room.

A challenge for predictive coding: Representational or experiential diversity?

2020 ◽  
Vol 43 ◽  
Author(s):  
Martina G. Vilas ◽  
Lucia Melloni
Keyword(s):  
Brain Function ◽  
Predictive Coding ◽  
Predictive Processing ◽  
Process Theory

Abstract To become a unifying theory of brain function, predictive processing (PP) must accommodate its rich representational diversity. Gilead et al. claim such diversity requires a multi-process theory, and thus is out of reach for PP, which postulates a universal canonical computation. We contend this argument and instead propose that PP fails to account for the experiential level of representations.

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