scholarly journals The Magnitude of Tobacco Smoking-Betel Quid Chewing-Alcohol Drinking Interaction Effect on Oral Cancer in South-East Asia. A Meta-Analysis of Observational Studies

PLoS ONE ◽  
2013 ◽  
Vol 8 (11) ◽  
pp. e78999 ◽  
Author(s):  
Stefano Petti ◽  
Mohd Masood ◽  
Crispian Scully
Keyword(s):  
Oral Cancer ◽  
East Asia ◽  
Tobacco Smoking ◽  
Interaction Effect ◽  
Alcohol Drinking ◽  
Observational Studies ◽  
Meta Analysis ◽  
Betel Quid ◽  
South East Asia ◽  
Betel Quid Chewing

Surgical outcomes and prognostic factors of oral cancer associated with betel quid chewing and tobacco smoking in Taiwan

Oral Oncology ◽  
2010 ◽  
Vol 46 (4) ◽  
pp. 276-282 ◽  
Author(s):  
Shyun-Yeu Liu ◽  
Chin-Li Lu ◽  
Chang-Ta Chiou ◽  
Ching-Yu Yen ◽  
Gwo-An Liaw ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Oral Cancer ◽  
Tobacco Smoking ◽  
Surgical Outcomes ◽  
Betel Quid ◽  
Betel Quid Chewing

scholarly journals Tobacco-Smoking, Alcohol-Drinking, and Betel-Quid-Chewing Behaviors: Development and Use of a Web-Based Survey System

2018 ◽  
Vol 6 (6) ◽  
pp. e142 ◽  
Author(s):  
Kuo-Yao Hsu ◽  
Yun-Fang Tsai ◽  
Chu-Ching Huang ◽  
Wen-Ling Yeh ◽  
Kai-Ping Chang ◽  
...  
Keyword(s):  
Tobacco Smoking ◽  
Alcohol Drinking ◽  
Betel Quid ◽  
Web Based ◽  
Betel Quid Chewing ◽  
Survey System

scholarly journals Combined Genetic Biomarkers and Betel Quid Chewing for Identifying High-Risk Group for Oral Cancer Occurrence

2017 ◽  
Vol 10 (6) ◽  
pp. 355-362 ◽  
Author(s):  
Chia-Min Chung ◽  
Chien-Hung Lee ◽  
Mu-Kuan Chen ◽  
Ka-Wo Lee ◽  
Cheng-Che E. Lan ◽  
...  
Keyword(s):  
High Risk ◽  
Oral Cancer ◽  
Risk Group ◽  
High Risk Group ◽  
Betel Quid ◽  
Genetic Biomarkers ◽  
Cancer Occurrence ◽  
Betel Quid Chewing

scholarly journals Alcohol drinking and gastric cancer risk: a meta-analysis of observational studies

Oncotarget ◽  
2017 ◽  
Vol 8 (58) ◽  
pp. 99013-99023 ◽  
Author(s):  
Peng-Liang Wang ◽  
Fang-Tao Xiao ◽  
Bao-Cheng Gong ◽  
Fu-Nan Liu
Keyword(s):  
Gastric Cancer ◽  
Cancer Risk ◽  
Alcohol Drinking ◽  
Observational Studies ◽  
Meta Analysis ◽  
Gastric Cancer Risk

scholarly journals Effects of alcohol consumption, cigarette smoking, and betel quid chewing on upper digestive diseases: a large cross-sectional study and meta-analysis

Oncotarget ◽  
2017 ◽  
Vol 8 (44) ◽  
pp. 78011-78022 ◽  
Author(s):  
Yun-Shiuan Chuang ◽  
Meng-Chieh Wu ◽  
Fang-Jung Yu ◽  
Yao-Kuang Wang ◽  
Chien-Yu Lu ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Cigarette Smoking ◽  
Meta Analysis ◽  
Cross Sectional Study ◽  
Betel Quid ◽  
Sectional Study ◽  
Cross Sectional ◽  
Digestive Diseases ◽  
Betel Quid Chewing

Impact of HOTAIR Gene Polymorphism and Environmental Risk on Oral Cancer

2018 ◽  
Vol 97 (6) ◽  
pp. 717-724 ◽  
Author(s):  
S.C. Su ◽  
M.J. Hsieh ◽  
C.W. Lin ◽  
C.Y. Chuang ◽  
Y.F. Liu ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Odds Ratio ◽  
Gene Polymorphisms ◽  
Clinical Stage ◽  
Interactive Effect ◽  
Clinical Status ◽  
Betel Quid ◽  
Nucleotide Polymorphisms ◽  
Advanced Clinical Stage ◽  
Betel Quid Chewing

Genetic and acquired factors are thought to be interrelated and imperative to estimate the risk and prognosis of oral squamous cell carcinoma (OSCC). HOX transcript antisense intergenic RNA ( HOTAIR) plays crucial roles in gene regulation and is regulated in a variety of cancers. Polymorphisms in HOTAIR have been recently linked to the predisposition to diverse malignancies. In the present study, we aimed to evaluate the influences of HOTAIR gene polymorphisms, combined with environmental triggers, on the susceptibility to oral tumorigenesis. Four single-nucleotide polymorphisms of the HOTAIR gene— rs920778, rs1899663, rs4759314, and rs12427129—were tested in 1,200 control participants and 907 patients with OSCC. We detected a significant association of rs1899663 with the risk of OSCC (adjusted odds ratio, 2.227; 95% confidence interval [95% CI], 1.197 to 4.146; P = 0.012) after adjustment for 3 potential confounders: smoking, betel quid chewing, and alcohol consumption. In further analyses where habitual exposure to each of 3 environmental factors was excluded, we found that, in addition to rs1899663, non–betel quid users who carried the polymorphic allele of rs920778 were more prone to develop OSCC than were those homozygous for wild-type allele (TC: odds ratio [OR], 1.472; 95% CI, 1.069 to 2.029; P = 0.018; TC+CC: OR, 1.448; 95% CI, 1.060 to 1.977; P = 0.020). Moreover, in exploring the relationship between HOTAIR gene polymorphisms and the clinical status of only patients with OSCC who were non–betel quid chewers (excluding the advanced clinical stage), we found that rs920778 and rs4759314 were correlated with the development of large-size tumors (OR, 1.891; 95% CI, 1.027 to 3.484; P = 0.04) and increased lymph node metastasis (OR, 4.140; 95% CI, 1.785 to 9.602; P = 0.001), respectively. Further functional assessments link rs920778 to the regulation of HOTAIR expression and epigenetic status. Our results reveal an interactive effect of HOTAIR gene polymorphisms and betel quid chewing on the development and progression of oral cancer.

scholarly journals Zika Virus and Arthritis/Arthralgia: A Systematic Review and Meta-Analysis

Viruses ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 1137
Author(s):  
B.M.C.R. Wimalasiri-Yapa ◽  
Harith E. Yapa ◽  
Xiaodong Huang ◽  
Louise M. Hafner ◽  
Tony J. Kenna ◽  
...  
Keyword(s):  
East Asia ◽  
Zika Virus ◽  
Meta Analysis ◽  
Symptom Burden ◽  
Cochrane Collaboration ◽  
Population Based ◽  
South East Asia ◽  
Zikv Infection ◽  
Pooled Prevalence ◽  
Rheumatic Manifestations

Dengue, chikungunya and Zika viruses share similar disease features, rendering them difficult to distinguish clinically. Incapacitating arthralgia/arthritis is a specific manifestation associated with chikungunya virus infection. However, the profile of arthralgia/arthritis in Zika virus (ZIKV) cases has not been well characterized. Articles were extracted from PubMed and Scopus databases reporting original data from patients with arthralgia/arthritis, according to the Cochrane Collaboration. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, 137 articles reporting ZIKV-associated joint symptoms were reviewed. Arthralgia was more frequently reported (n = 124 from case studies, n = 1779 from population-based studies) than arthritis (n = 7 and n = 121, respectively). Arthralgia was resolved in <1 week in 54%, and within 1–2 weeks in 40% of cases. The meta-analysis of cases in population-based studies identified a pooled prevalence of 53.55% for arthralgia. The pooled prevalence of arthralgia/arthritis during outbreaks depended on the geographic location, with a higher joint symptom burden observed in the Americas compared to South East Asia (Brazil: 60.79%; Puerto Rico: 68.89% and South East Asia: 26.46%). We conclude that non-specific constitutional arthralgia is the most common joint manifestation during ZIKV infection, being present in nearly half of cases but resolving by two weeks in >90% of these. We found no evidence of chronic rheumatic manifestations following ZIKV infection.

scholarly journals Acrolein is involved in the synergistic potential of cigarette smoking- and betel quid chewing-related human oral cancer.

2019 ◽  
pp. cebp.1033.2018 ◽  
Author(s):  
Hsiang-Tsui Wang ◽  
Han-Hsing Tsou ◽  
Chih-Hung Hu ◽  
Jin-Hui Liu ◽  
Chung-Ji Liu ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Cigarette Smoking ◽  
Betel Quid ◽  
Betel Quid Chewing
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