scholarly journals Flat Anterior Chamber after Trabeculectomy in Secondary Angle-Closure Glaucoma with BEST1 Gene Mutation: Case Series

PLoS ONE ◽  
2017 ◽  
Vol 12 (1) ◽  
pp. e0169395 ◽  
Author(s):  
Yimin Zhong ◽  
Xinxing Guo ◽  
Hui Xiao ◽  
Jingyi Luo ◽  
Chengguo Zuo ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Gene Mutation ◽  
Case Series ◽  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
Flat Anterior Chamber

scholarly journals Etiologies and clinical characteristics of young patients with angle-closure glaucoma: a 15-year single-center retrospective study

2021 ◽  
Author(s):  
Feng Gao ◽  
Jiajian Wang ◽  
Junyi Chen ◽  
Xiaolei Wang ◽  
Yuhong Chen ◽  
...  
Keyword(s):  
Clinical Characteristics ◽  
Anterior Segment ◽  
Young Patients ◽  
Case Series ◽  
Neovascular Glaucoma ◽  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
Primary Angle Closure Glaucoma ◽  
Uncommon Presentation ◽  
Underlying Causes

Abstract Purpose To investigate the etiologies and the clinical characteristics of angle-closure glaucoma (ACG) patients younger than 40 years old in Chinese. Methods Inpatients with diagnosis of ACG and diagnosed age younger than or equal to 40 years old, who were admitted in Eye, Ear, Nose, and Throat Hospital Fudan University from 2002 to 2017, were included in this retrospective non-comparative case series. The underlying causes and clinical features for all the patients were analyzed by comprehensive review of medical charts. Results A total of 298 patients (463 eyes) met the criteria, including 153 females (51.3%) and 145 males (48.7%); the mean age was 25.6 ± 13.0 years. Primary angle-closure glaucoma (PACG), uveitis, and anterior segment dysgenesis (ASD) were the top three etiologies in our patients, which accounted for 32.6%, 20.3%, and 15.1% of the total patients respectively. PACG mainly occurs after 30 years of age and ASD is the top reason of ACG in patients younger than 20 years old. Other known etiologies include iridocorneal endothelial syndrome, neovascular glaucoma, nanophthalmos, retinitis pigmentosa, spherophakia, bestrophinopathy, persistent fetal vasculature, iridociliary cysts, congenital retinoschisis, Marfan’s syndrome, retinopathy of prematurity, familial exudative vitreoretinopathy, congenital retinal folds, Coat’s disease, and neurofibromatosis. Conclusions We described the uncommon presentation of ACG in Chinese young patients. Although unusual, most of the etiologies could be identified. Therefore, more careful and comprehensive examinations are needed for early detection and timely treatment for young ACG patients.

Case series of angle-closure glaucoma after laser treatment for retinopathy of prematurity

2005 ◽  
Vol 9 (1) ◽  
pp. 17-21 ◽  
Author(s):  
Lucas Trigler ◽  
R. Grey Weaver ◽  
James W. O’Neil ◽  
Michael J. Barondes ◽  
Sharon F. Freedman
Keyword(s):  
Laser Treatment ◽  
Retinopathy Of Prematurity ◽  
Case Series ◽  
Angle Closure Glaucoma ◽  
Angle Closure

scholarly journals ABCC5, a Gene That Influences the Anterior Chamber Depth, Is Associated with Primary Angle Closure Glaucoma

PLoS Genetics ◽  
2014 ◽  
Vol 10 (3) ◽  
pp. e1004089 ◽  
Author(s):  
Monisha E. Nongpiur ◽  
Chiea Chuen Khor ◽  
Hongyan Jia ◽  
Belinda K. Cornes ◽  
Li-Jia Chen ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Anterior Chamber Depth ◽  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
Primary Angle Closure ◽  
Primary Angle Closure Glaucoma

scholarly journals Combined Acute Haemolytic and Secondary Angle Closure Glaucoma following Spontaneous Intraocular Haemorrhages in a Patient on Warfarin

2016 ◽  
Vol 7 (3) ◽  
pp. 511-516 ◽  
Author(s):  
Walter Andreatta ◽  
Stavroula Boukouvala ◽  
Atul Bansal
Keyword(s):  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Acute Angle ◽  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
First Case ◽  
Oral Warfarin ◽  
Acute Angle Closure ◽  
Excessive Anticoagulation ◽  
Acute Angle Closure Glaucoma

Background: To report the first described case of combined haemolytic and acute angle closure glaucoma secondary to spontaneous intraocular haemorrhages in a patient on excessive anticoagulation. To the best of our knowledge, this is the first case reported in the literature presenting with raised intraocular pressure due to both mechanisms. Case Description: A 90-year-old woman presented with acute pain and reduction in vision in the left eye. Her intraocular pressure (IOP) was 55 mm Hg. There were red tinted blood cells in the anterior chamber giving it a reddish hue. The patient was known to have advanced wet macular degeneration. She was taking oral warfarin for atrial fibrillation. Her international normalised ratio (INR) was 7.7. B-scan ultrasound of posterior segment showed vitreous and suprachoroidal haemorrhages. An ultrabiomicroscopic examination confirmed open angles. A diagnosis of haemolytic glaucoma secondary to intraocular haemorrhages was made. The IOP was controlled medically. Warfarin was withdrawn and oral vitamin K therapy was initiated leading to a rapid INR reduction. Three days later, her anterior chamber became progressively shallower causing a secondary acute angle closure which was managed medically. After 2 months, the left IOP was well-controlled without any medications and the eye was not inflamed. Her vision in that eye remained perception of light. Conclusion: Patients with suprachoroidal haemorrhages should be closely monitored as they might subsequently develop acute angle closure despite an initially open angle and well-controlled INR and IOP. Excessive anticoagulation needs to be prevented to minimise the risk of sight-threatening complications.

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