Cross-sectional study of the association between day-to-day home blood pressure variability and visceral fat area measured using the dual impedance method

ObjectivesRecent studies reported that 24-hour ambulatory blood pressure variability (ABPV) was associated with lacunar infarction and white matter hyperintensities (WMH). However, the relationship between ABPV and enlarged perivascular spaces (EPVS) has not been investigated. Thus, our study aimed to investigate whether ABPV is associated with EPVS by 24-hour ambulatory blood pressure monitoring (ABPM).DesignWe conducted this study as a cross-sectional study.SettingsThe study was based on patients who presented for physical examinations in our hospital from May 2013 to June 2016.ParticipantsPatients with both brain MRI scans and 24-hour ABPM were included and patients with acute stroke, a history of severe stroke and some other severe diseases were excluded. A total of 573 Chinese patients were prospectively enrolled in this study.Primary and secondary outcome measuresEPVS in basal ganglia (BG) and white matter (WM) were identified on MRI and classified into three categories by the severity. WMH were scored by the Fazekas scale. Coefficient of variation (CV) and SD were considered as metrics of ABPV. Spearman correlation analysis and ordinal logistic regression analysis were used to assess the relationship between ABPV and EPVS.ResultsThere were statistical differences among the subgroups stratified by the severity of EPVS in BG in the following ABPV metrics: SD and CV of systolic blood pressure (SBP), CV of diastolic blood pressure (DBP) in 24 hours, daytime and nighttime and SD of DBP in nighttime. The above ABPV metrics were positively associated with the degree of EPVS. The association was unchanged after adjusting for confounders. Spearman correlation analysis showed ABPV was not related to the degree of EPVS in the WM.ConclusionABPV was independently associated with EPVS in BG after controlling for blood pressure, but not in the WM. Pathogenesis of EPVS in BG and WM might be different.

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Association between breath methane concentration and visceral fat area: a population-based cross-sectional study

Journal of Breath Research ◽

10.1088/1752-7163/ab61c6 ◽

2020 ◽

Vol 14 (2) ◽

pp. 026008

Author(s):

Naoki Ozato ◽

Shinichiro Saito ◽

Tohru Yamaguchi ◽

Mitsuhiro Katashima ◽

Itoyo Tokuda ◽

...

Keyword(s):

Visceral Fat ◽

Methane Concentration ◽

Population Based ◽

Cross Sectional Study ◽

Sectional Study ◽

Visceral Fat Area ◽

Cross Sectional ◽

Breath Methane

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How Accurate Are Home Blood Pressure Devices in Use? A Cross-Sectional Study

PLoS ONE ◽

10.1371/journal.pone.0155677 ◽

2016 ◽

Vol 11 (6) ◽

pp. e0155677 ◽

Cited By ~ 13

Author(s):

Marcel Ruzicka ◽

Ayub Akbari ◽

Eva Bruketa ◽

Jeanne Françoise Kayibanda ◽

Claude Baril ◽

...

Keyword(s):

Blood Pressure ◽

Cross Sectional Study ◽

Home Blood Pressure ◽

Sectional Study ◽

Cross Sectional

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Impact of body mass index on long-term blood pressure variability: a cross-sectional study in a cohort of Chinese adults

BMC Public Health ◽

10.1186/s12889-018-6083-4 ◽

2018 ◽

Vol 18 (1) ◽

Cited By ~ 11

Author(s):

Haojia Chen ◽

Ruiying Zhang ◽

Qiongbing Zheng ◽

Xiuzhu Yan ◽

Shouling Wu ◽

...

Keyword(s):

Blood Pressure ◽

Body Mass Index ◽

Body Mass ◽

Blood Pressure Variability ◽

Cross Sectional Study ◽

Sectional Study ◽

Chinese Adults ◽

Cross Sectional

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Correlation of Visceral Fat Area with Metabolic Risk Factors in Romanian Patients: A Cross-Sectional Study

Romanian Journal of Diabetes Nutrition and Metabolic Diseases ◽

10.1515/rjdnmd-2015-0046 ◽

2015 ◽

Vol 22 (4) ◽

pp. 393-402 ◽

Cited By ~ 1

Author(s):

Anca Hâncu ◽

Gabriela Radulian

Keyword(s):

Risk Factors ◽

Waist Circumference ◽

Visceral Fat ◽

Cross Sectional Study ◽

Liver Fat ◽

Sectional Study ◽

Visceral Fat Area ◽

Cross Sectional ◽

Previous Diagnosis ◽

Obesity Hypertension

AbstractBackground and Aims: The aim of the present study was to investigate the relationship between visceral fat area (VFA), estimated by bioimpedance, and cardiovascular risk factors independent of BMI and waist circumference in a cohort of Romanian patients. Material and Methods: This was a cross-sectional study, in which were collected data from 751 patients ≥18 years of age from Cluj-Napoca. Anthropometric, biochemistry, body composition and medical history parameters were recorded from patients’ files. Results: Compared with the participants with VFA <100 cm2, those with VFA ≥100 cm2had significantly worse levels of the laboratory parameters describing the glycemic metabolism, lipid metabolism and liver functions (p <0.05 for all). A higher percentage of participants with VFA ≥100 cm2had diabetes, obesity, hypertension, hypertriglyceridemia and hypo-HDL cholesterolemia (p <0.05 for all). VFA was correlated with systolic and diastolic blood pressure, total and LDL-cholesterol levels, triglycerides, ALT, previous diagnosis of diabetes, hypertriglyceridemia and hypo-HDL cholesterolemia independent of BMI and waist circumference. Conclusions: Among this cohort of Romanian adults, an increasing level of visceral adiposity was correlated with worse lipid and glucose metabolism parameters as well as with increased levels of ALT, which probably reflects liver fat deposition.

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The visceral fat area to leg muscle mass ratio is significantly associated with the risk of hyperuricemia among women: a cross-sectional study

Biology of Sex Differences ◽

10.1186/s13293-021-00360-9 ◽

2021 ◽

Vol 12 (1) ◽

Author(s):

Xiao-He Wang ◽

Wei-Ran Jiang ◽

Min-Ying Zhang ◽

Ying-Xin Shi ◽

Yun-Ping Ji ◽

...

Keyword(s):

Visceral Fat ◽

Density Lipoprotein ◽

Positive Association ◽

Cross Sectional Study ◽

Sectional Study ◽

Significant Positive Association ◽

Visceral Fat Area ◽

Cross Sectional ◽

Menopausal Women ◽

Leg Muscle

Abstract Background A significant positive association was found in previous studies among obesity, visceral fat accumulation, and hyperuricemia. The purpose of this study was to explore the association between the ratio of visceral fat area to leg muscle mass (VFA-to-LMM) and hyperuricemia, and verify the role of gender differences in the association. Methods A total of 3393 (43.3% are men) participants from Tianjin Union Medical Center-Health Management Center were recruited for this cross-sectional study. The VFA-to-LMM ratio was used as the independent variable. Hyperuricemia, a serum uric acid level ≥ 416 μmol/L in men and in menopausal women and ≥ 357 μmol/L in premenopausal women, was used as the dependent variable. Multiple logistic regression analysis was used to estimate the odds ratio and the 95% confidence interval between the VFA-to-LMM ratio and hyperuricemia. Results The overall prevalence of hyperuricemia was 14.8% (8.9% in women, and 22.5% in men). After adjustment by age, smoking status (for males), menopause status (for females), drinking status, exercise frequency, blood pressure, alanine aminotransferase, fasting plasma glucose, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, creatinine, and history of diseases, a strong positive association was found between the VFA-to-LMM ratio and hyperuricemia in both men (4th vs. 1st quartile 1.60, 95%CI: 1.03–2.49) and women (4th vs. 1st quartile 5.22, 95%CI: 2.44–12.56). After additional adjustment by BMI, there was still a significant positive association in women (4th vs. 1st quartile 2.57, 95%CI: 1.06–6.77). The results of subgroup analysis showed that pre-menopausal women (4th vs. 1st quartile OR: 3.61) have a higher risk of hyperuricemia than postmenopausal women (4th vs. 1st quartile OR: 1.94) with the increase of the VFA-to-LMM ratio. Besides, the interaction analysis results showed the highest risk of hyperuricemia when VFA and LMM were both in the highest quantile (OR: 11.50; 95% CI: 4.86–31.98). Conclusion The VFA-to-LMM ratio was positively associated with the risk of hyperuricemia in women after adjustment by confounders. Pre-menopausal women have a higher risk of hyperuricemia than postmenopausal women with the increase of the VFA-to-LMM ratio. In addition, the highest risk of hyperuricemia was demonstrated when both VFA and LMM were at the highest quartile.

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Visceral Fat Area to Leg Muscle Mass Ratio Are Significantly Associated With the Risk of Hyperuricemia Among Women: A Cross-sectional Study

10.21203/rs.3.rs-28417/v1 ◽

2020 ◽

Author(s):

Xiao-He WANG ◽

Wei-Ran JIANG ◽

Min-Ying ZHANG ◽

Ying-Xin SHI ◽

Yun-Ping JI ◽

...

Keyword(s):

Muscle Mass ◽

Visceral Fat ◽

Density Lipoprotein ◽

Positive Association ◽

Cross Sectional Study ◽

Sectional Study ◽

Significant Positive Association ◽

Visceral Fat Area ◽

Cross Sectional ◽

Leg Muscle

Abstract Background: Previous studies have found a significant positive association between obesity, visceral fat accumulation and hyperuricemia. The purpose of the study was to explore the association between the ratio of visceral fat area to leg muscle mass(VFA-to-LMM) and hyperuricemia, and verify the role of sex differences in the association.Methods:In this cross-sectional study, a total of 3393 (43.3% for men) participants from Tianjin Union Medical Center-Health Management Center were recruited. Body composition were measured by multielectrode bioelectrical impedance analyzer. The VFA-to-LMM ratio was used as independent variable. Hyperuricemia, defined as a serum uric acid level ≥ 416 μmol/L in men and menopausal women, and ≥ 357 μmol/L in premenopausal women, was used as the dependent variable. Multiple logistic regression analysis was used to estimate the odds ratio and 95% confidence interval between VFA-to-LMM ratio and hyperuricemia.Results:The overall prevalence of hyperuricemia was 14.8%, and the prevalence of hyperuricemia in women (8.9%) was significantly lower than that in men (22.5%). After adjustment for age, smoking status (for males), menopause status (for females), drinking status, exercise frequency, blood pressure, alanine aminotransferase, fasting plasma glucose, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, creatinine, and history of diseases, a strong positive association was observed between VFA-to-LMM ratio and hyperuricemiain bothmen (4th vs. 1st quartile 1.60, 95%CI: 1.03-2.49) and women (4th vs. 1st quartile 5.22, 95%CI: 2.44-12.56).After additionally adjustment for BMI, there was still a significant positive association in women (4th vs. 1st quartile 2.57, 95%CI: 1.06-6.77), while the association disappeared in men(4th vs. 1st quartile 0.97, 95%CI: 0.55-1.70).Conclusions:The VFA-to-LMM ratio was positively associated with the risk of hyperuricemia in women after adjustments for confounders. In addition, the highest risk of hyperuricemia was observed when both VFA and LMM were at the highest quartile. However, well-controlled prospective studies are needed to further confirm the causality between VFA-to-LMM ratio and hyperuricemia.

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