scholarly journals Human milk-based fortifier is associated with less alteration of milk fat globule size than cow milk-based fortifier

PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0257491
Author(s):  
Yurika Yoshida ◽  
Minami Azuma ◽  
Haruhiro Kuwabara ◽  
Tokuo Miyazawa ◽  
Yuya Nakano ◽  
...  
Keyword(s):  
Human Milk ◽  
Milk Fat ◽  
Cow Milk ◽  
Very Preterm Infants ◽  
Very Preterm ◽  
Fortified Milk ◽  
Globule Size ◽  
Milk Fat Globule ◽  
Fat Globule ◽  
Feeding Tolerance

We aimed to evaluate if human milk-based fortifier (HMBF) affects human milk fat globule (MFG) size less than cow milk-based fortifier (CMBF), which may impact overall infant feeding tolerance. Measurements of donated human milk were performed before fortification as well as at 1 hour, 24 hours, and 48 hours after fortification with CMBF or HMBF. MFG size in each sample of fortified milk was measured by laser light scattering. MFG size in the fortified milks increased gradually over time. At 24 and 48 hours after fortification, MFG size in the milk with CMBF was larger than that in the milk with HMBF (4.8 ± 0.5 vs 4.3 ± 0.3 μm, p<0.01, 5.1 ± 0.7 vs 4.5 ± 0.4 μm, p = 0.03, respectively). HMBF is associated with less alteration of MFG size than CMBF. This may have an impact on feeding tolerance of very preterm infants.

Structure of the human milk fat globule

2013 ◽  
Vol 25 (10) ◽  
pp. 223-226 ◽  
Author(s):  
Cyrielle Garcia ◽  
Sheila Innis
Keyword(s):  
Human Milk ◽  
Milk Fat ◽  
Milk Fat Globule ◽  
Fat Globule ◽  
Human Milk Fat

scholarly journals Isolation and characterization of two individual glycoprotein components from human milk-fat-globule membranes

1982 ◽  
Vol 207 (1) ◽  
pp. 37-41 ◽  
Author(s):  
A Imam ◽  
D J Laurence ◽  
A M Neville
Keyword(s):  
Human Milk ◽  
Milk Fat ◽  
Sodium Dodecyl ◽  
Membrane Glycoproteins ◽  
Lectin Affinity Chromatography ◽  
Isolation And Characterization ◽  
Milk Fat Globule ◽  
Fat Globule ◽  
Milk Fat Globule Membranes ◽  
Human Milk Fat

Two individual glycoprotein components from human milk-fat-globule membranes (MFGM) has been purified by selectively extracting the membrane glycoproteins followed by lectin affinity chromatography and gel filtration on Sephadex G-200 in the presence of protein-disaggregating agents. The purified glycoprotein components, termed ‘epithelial-membrane glycoprotein’ (EMGP-155 and EMGP-39) have estimated molecular weights of 155 000 and 39 000 respectively, and yield a single band under reducing conditions on sodium dodecyl sulphate/polyacrylamide gel. EMGP-155 and EMGP-39 contain 21.0% and 7.0% carbohydrate by weight, with fucose (13.5%, 12.4%), mannose (3.7%, 6.2%), galactose (28.5%, 22.6%), N-acetylglucosamine (17.8%, 7.4%) and sialic acid (36.4%, 51.4%) of the carbohydrate moiety respectively. For both the glycoprotein components, aspartic and glutamic acid and serine are the major amino acid residues.

Radiation doses obtained from 99mTc-labelled human milk fat globule monoclonal antibodies

1993 ◽  
Vol 20 (2) ◽  
pp. 145-148
Author(s):  
M.M. Calitz ◽  
A. Van Aswegen ◽  
M.M.J. Van Der Merwe ◽  
M.G. Lötter
Keyword(s):  
Monoclonal Antibodies ◽  
Human Milk ◽  
Milk Fat ◽  
Radiation Doses ◽  
Milk Fat Globule ◽  
Fat Globule ◽  
Human Milk Fat

scholarly journals A novel FADS2 isoform identified in human milk fat globule suppresses FADS2 mediated Δ6-desaturation of omega-3 fatty acids

2018 ◽  
Vol 138 ◽  
pp. 52-59 ◽  
Author(s):  
Kumar S.D. Kothapalli ◽  
Hui Gyu Park ◽  
Xiaoxian Guo ◽  
Xuepeng Sun ◽  
James Zou ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Human Milk ◽  
Milk Fat ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Milk Fat Globule ◽  
Fat Globule ◽  
Human Milk Fat

scholarly journals Composition of Milk Fat from Cows Selected for Milk Fat Globule Size and Offered Either Fresh Pasture or a Corn Silage-Based Diet

2007 ◽  
Vol 90 (1) ◽  
pp. 392-403 ◽  
Author(s):  
S. Couvreur ◽  
C. Hurtaud ◽  
P.G. Marnet ◽  
P. Faverdin ◽  
J.L. Peyraud
Keyword(s):  
Milk Fat ◽  
Corn Silage ◽  
Globule Size ◽  
Milk Fat Globule ◽  
Fat Globule

Reactions of Monoclonal Antibodies against Human Milk Fat Globule Membranes with Embryonal Tissue

1984 ◽  
pp. 1021-1024 ◽  
Author(s):  
U. KOLDOVSKY ◽  
U. WARGALLA ◽  
J. HILKENS ◽  
J. TAYLOR-PAPADIMITRIOU ◽  
PH. HAGEMANN ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Human Milk ◽  
Milk Fat ◽  
Milk Fat Globule ◽  
Fat Globule ◽  
Milk Fat Globule Membranes ◽  
Human Milk Fat
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