scholarly journals Uninterrupted HIV treatment for women: Policies and practices for care transitions during pregnancy and breastfeeding in Côte d’Ivoire, Lesotho and Malawi

PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0260530
Author(s):  
Tamsin K. Phillips ◽  
Halli Olsen ◽  
Chloe A. Teasdale ◽  
Amanda Geller ◽  
Mamorapeli Ts’oeu ◽  
...  

Transitions between services for continued antiretroviral treatment (ART) during and after pregnancy are a commonly overlooked aspect of the HIV care cascade, but ineffective transitions can lead to poor health outcomes for women and their children. In this qualitative study, we conducted interviews with 15 key stakeholders from Ministries of Health along with PEPFAR-supported and other in-country non-governmental organizations actively engaged in national programming for adult HIV care and prevention of mother-to-child-transmission of HIV (PMTCT) services in Côte d’Ivoire, Lesotho and Malawi. We aimed to understand perspectives regarding transitions into and out of PMTCT services for continued ART. Thematic analysis revealed that, although transitions of care are necessary and a potential point of loss from ART care in all three countries, there is a lack of clear guidance on transition approach and no formal way of monitoring transition between services. Several opportunities were identified to monitor and strengthen transitions of care for continued ART along the PMTCT cascade.

BMC Nutrition ◽  
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Julie Jesson ◽  
Ayoko Ephoevi-Ga ◽  
Marie-Hélène Aké-Assi ◽  
Sikiratou Koumakpai ◽  
Sylvie N’Gbeche ◽  
...  

Abstract Background Nutritional care is not optimally integrated into pediatric HIV care in sub-Saharan Africa. We assessed the 6-month effect of a nutritional support provided to children living with HIV, followed in a multicentric cohort in West Africa. Methods In 2014-2016, a nutritional intervention was carried out for children living with HIV, aged under 10 years, receiving antiretroviral therapy (ART) or not, in five HIV pediatric cohorts, in Benin, Togo and Côte d’Ivoire. Weight deficiency was assessed using two definitions: wasting (Weight for Height Z-score [WHZ] for children<5 years old or Body-Mass-Index for Age [BAZ] for ≥5 years) and underweight (Weight for Age Z-score [WAZ]) (WHO child growth standards). Combining these indicators, three categories of nutritional support were defined: 1/ children with severe malnutrition (WAZ and/or WHZ/BAZ <-3 Standard Deviations [SD]) were supported with Ready-To-Use Therapeutic Food (RUTF), 2/ those with moderate malnutrition (WAZ and/or WHZ/BAZ = [-3;-2[ SD) were supported with fortified blended flours produced locally in each country, 3/ those non malnourished (WAZ and WHZ/BAZ ≥-2 SD) received nutritional counselling only. Children were followed monthly over 6 months. Dietary Diversity Score (DDS) using a 24h recall was measured at the first and last visit of the intervention. Results Overall, 326 children were included, 48% were girls. At baseline, 66% were aged 5-10 years, 91% were on ART, and 17% were severely immunodeficient (CD4 <250 cells/mL or CD4%<15). Twenty-nine (9%) were severely malnourished, 63 (19%) moderately malnourished and 234 (72%) non-malnourished. After 6 months, 9/29 (31%) and 31/63 (48%) recovered from severe and moderate malnutrition respectively. The median DDS was 8 (IQR 7-9) in Côte d’Ivoire and Togo, 6 (IQR 6-7) in Benin. Mean DDS was 4.3/9 (sd 1.2) at first visit, with a lower score in Benin, but with no difference between first and last visit (p=0.907), nor by intervention groups (p-value=0.767). Conclusions This intervention had a limited effect on nutritional recovery and dietary diversity improvement. Questions remain on determining appropriate nutritional products, in terms of adherence, proper use for families and adequate energy needs coverage for children living with HIV. Trial registration PACTR202001816232398, June 01, 2020, retrospectively registered.


2016 ◽  
Vol 9 (1) ◽  
pp. 31622 ◽  
Author(s):  
Shino Arikawa ◽  
Tanoh Eboua ◽  
Kouadio Kouakou ◽  
Marie-Sylvie N'Gbeche ◽  
Madeleine Amorissani-Folquet ◽  
...  

PLoS Medicine ◽  
2009 ◽  
Vol 6 (10) ◽  
pp. e1000173 ◽  
Author(s):  
Elena Losina ◽  
Hapsatou Touré ◽  
Lauren M. Uhler ◽  
Xavier Anglaret ◽  
A. David Paltiel ◽  
...  

PLoS ONE ◽  
2019 ◽  
Vol 14 (3) ◽  
pp. e0211385 ◽  
Author(s):  
Natalie Jean Tibbels ◽  
Zoé Mistrale Hendrickson ◽  
Danielle Amani Naugle ◽  
Abdul Dosso ◽  
Lynn Van Lith ◽  
...  

2006 ◽  
Vol 355 (11) ◽  
pp. 1141-1153 ◽  
Author(s):  
Sue J. Goldie ◽  
Yazdan Yazdanpanah ◽  
Elena Losina ◽  
Milton C. Weinstein ◽  
Xavier Anglaret ◽  
...  

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Nicolas Rouveau ◽  
◽  
Odette Ky-Zerbo ◽  
Sokhna Boye ◽  
Arlette Simo Fotso ◽  
...  

Abstract Background The ATLAS programme aims to promote and implement HIV self-testing (HIVST) in three West African countries: Côte d’Ivoire, Mali, and Senegal. During 2019–2021, in close collaboration with the national AIDS implementing partners and communities, ATLAS plans to distribute 500,000 HIVST kits through eight delivery channels, combining facility-based, community-based strategies, primary and secondary distribution of HIVST. Considering the characteristics of West African HIV epidemics, the targets of the ATLAS programme are hard-to-reach populations: key populations (female sex workers, men who have sex with men, and drug users), their clients or sexual partners, partners of people living with HIV and patients diagnosed with sexually transmitted infections and their partners. The ATLAS programme includes research support implementation to generate evidence for HIVST scale-up in West Africa. The main objective is to describe, analyse and understand the social, health, epidemiological effects and cost-effectiveness of HIVST introduction in Côte d’Ivoire, Mali and Senegal to improve the overall HIV testing strategy (accessibility, efficacy, ethics). Methods ATLAS research is organised into five multidisciplinary workpackages (WPs): Key Populations WP: qualitative surveys (individual in-depth interviews, focus group discussions) conducted with key actors, key populations, and HIVST users. Index testing WP: ethnographic observation of three HIV care services introducing HIVST for partner testing. Coupons survey WP: an anonymous telephone survey of HIVST users. Cost study WP: incremental economic cost analysis of each delivery model using a top-down costing with programmatic data, complemented by a bottom-up costing of a representative sample of HIVST distribution sites, and a time-motion study for health professionals providing HIVST. Modelling WP: Adaptation, parameterisation and calibration of a dynamic compartmental model that considers the varied populations targeted by the ATLAS programme and the different testing modalities and strategies. Discussion ATLAS is the first comprehensive study on HIV self-testing in West Africa. The ATLAS programme focuses particularly on the secondary distribution of HIVST. This protocol was approved by three national ethic committees and the WHO’s Ethical Research Committee.


2017 ◽  
Vol 22 (4) ◽  
pp. 431-441 ◽  
Author(s):  
Margaret L. McNairy ◽  
Jules B. Bashi ◽  
Hannah Chung ◽  
Louise Wemin ◽  
Marie-Nicole Akpro Lorng ◽  
...  

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