scholarly journals S2125 IgG4-Related Esophageal Stenosis Treated With Serial Endoscopic Dilation and Concurrent Steroid Injection

2021 ◽  
Vol 116 (1) ◽  
pp. S914-S914
Author(s):  
Emad A. Chishti ◽  
Ujas P. Patel ◽  
Moamen M. Gabr ◽  
Bahaaeldeen S. Ismail
2016 ◽  
Vol 23 (4) ◽  
pp. 218-223 ◽  
Author(s):  
Marlene Abreu ◽  
Isabel Nunes ◽  
Susana Corujeira ◽  
Marta Tavares ◽  
Eunice Trindade ◽  
...  

Endoscopy ◽  
2020 ◽  
Vol 52 (09) ◽  
pp. 721-726
Author(s):  
Chandra S. Dasari ◽  
Ramprasad Jegadeesan ◽  
Harsh K. Patel ◽  
Madhav Desai ◽  
Muhammad Aziz ◽  
...  

Abstract Background Post-esophagectomy anastomotic strictures are difficult to treat. The impact of adding local steroid injection to endoscopic dilation for the treatment of post-esophagectomy anastomotic strictures is unclear. We conducted a systematic review and meta-analysis to assess the efficacy of performing steroid injection in addition to dilation. Methods A search was conducted in MEDLINE, Cochrane Library, EMBASE, and Web of Science from inception to January 2019. Randomized controlled trials (RCTs) comparing the efficacy of endoscopic dilation plus either local steroid injection (steroid group) or saline injection (placebo group) were included in the analysis. Results Three RCTs were eligible for the final analysis: 72 patients (mean age 61.3 years, 74 % male) in the steroid group and 72 patients (mean age 59.6 years, 71 % male) in the placebo group. The mean number of dilations required to resolve the stricture was significantly lower in the steroid group compared with the placebo group, with a mean weighted difference of –1.62 (95 % confidence interval [CI] –2.73 to –0.50; P = 0.004). After 6 months of follow-up, there was a trend toward more patients in the steroid group remaining dysphagia free compared with the placebo group, with a pooled odds ratio of 2.36 (95 %CI 0.94 to 5.91; P = 0.07, I2  = 24 %). Conclusion This meta-analysis showed that the addition of local steroid injection at the time of dilation for benign anastomotic strictures led to a significant decrease in the number of procedures required to resolve the stricture and may well reduce dysphagia symptoms during follow-up.


2019 ◽  
Vol 32 (Supplement_1) ◽  
Author(s):  
M Deganello Saccomani ◽  
V Bortolotti ◽  
A Gastaldi ◽  
F S Camoglio ◽  
G Piacentini ◽  
...  

Abstract Objective and Study Esophageal stenosis is the most common morbidity associated with congenital esophageal atresia (EA). There is no consensus regarding the endoscopic management of strictures in terms of timing and techniques of dilations. The aim of this study is to describe the endoscopic management of esophageal stenosis in children with EA admitted to our tertiary care center. Methods A retrospective descriptive single-center study was conducted. Data were collected of all patients diagnosed with EA admitted to the ‘Women's and Children's Hospital’ of Verona, Italy, between 2004 and 2017. Results Thirty-seven patients with EA were admitted to our center between 2004 and 2017. Twenty of them were excluded for insufficient data. All patients underwent surgical correction within 2 months of life. An endoscopic control with upper gastrointestinal endoscopy was performed in all of them. Eleven (65%) subjects had tracheoesophageal fistula. All of them had type C EA. Three (18%) had long-gap EA. Eleven patients (65%), 8 with Type C EA and 3 with Type A EA, underwent endoscopic dilation. Semirigid Savary-Giliard bougies were used in most of them. Pneumatic dilation with balloon was performed only in one case. Nine (81%) needed more than one dilation due to anastomotic stricture recurrence. In 3 of the 11 subjects (27%) more than 3 dilations were necessary. Two of them had long-gap EA. The median age of first endoscopic dilation was 3 months (range: 1–12 months). The median age of the last dilation was 6 months (range: 1–18 months). One of the 11 patients who underwent dilations (Type C EA with long gap) underwent surgical retreatment due to fistula recurrence. Six of the 17 subjects (35%) enrolled developed long-term complications. Conclusion Our data confirmed that anastomotic stricture is frequent in patients with EA who underwent surgical correction. Endoscopic management of stenosis is a safe and effective procedure that leads to a limited number of complications. Side effects are more likely to occur in patients with long-gap EA. Timing of dilations and endoscopic technique should be defined by international guidelines in order to improve patient's outcome.


2012 ◽  
Vol 24 (6) ◽  
pp. 483-483 ◽  
Author(s):  
Joan B Gornals ◽  
José Nogueira ◽  
Josep M. Castellvi ◽  
Jordi Guardiola

2018 ◽  
Vol 113 (Supplement) ◽  
pp. S197-S198
Author(s):  
Shashank Sarvepalli ◽  
Malav P. Parikh ◽  
Swara Sarvepalli ◽  
Prasanthi N. Thota ◽  
Madhusudhan R. Sanaka

2014 ◽  
Vol 29 (10) ◽  
pp. 2953-2959 ◽  
Author(s):  
Yoshihiro Kishida ◽  
Naomi Kakushima ◽  
Noboru Kawata ◽  
Masaki Tanaka ◽  
Kohei Takizawa ◽  
...  

2021 ◽  
Author(s):  
F Ben Farhat ◽  
M Sabbah ◽  
N Bellil ◽  
D Trad ◽  
N Bibani ◽  
...  

10.37358/3700 ◽  
2019 ◽  
Vol 70 (10) ◽  
pp. 3700-3702

After caustic ingestion, patients may be either asymptomatic or may exhibit a variety of initial signs and symptoms, depending on the digestive segment predominantly affected. The DROOL system is a noninvasive scoring method used for the evaluation of esophageal lesions and has a good correlation with the development of esophageal stenosis. Management of these patients depends on several factors, including the presence of the symptomatology, in addition to the nature of the caustic substance. Upper endoscopy is indicated in the first 48 hours or after the first two weeks, when it is recommended to start endoscopic dilation sessions. If endoscopic treatment is inefficient, surgical treatment is required. Keywords: caustic ingestion, esophageal stenosis, esophageal bypass


2019 ◽  
Vol 70 (10) ◽  
pp. 3700-3702
Author(s):  
Rodica Daniela Birla ◽  
Petre Angel Hoara ◽  
Valeriu Gabi Dinca ◽  
Silviu Constantinoiu

After caustic ingestion, patients may be either asymptomatic or may exhibit a variety of initial signs and symptoms, depending on the digestive segment predominantly affected. The DROOL system is a noninvasive scoring method used for the evaluation of esophageal lesions and has a good correlation with the development of esophageal stenosis. Management of these patients depends on several factors, including the presence of the symptomatology, in addition to the nature of the caustic substance. Upper endoscopy is indicated in the first 48 hours or after the first two weeks, when it is recommended to start endoscopic dilation sessions. If endoscopic treatment is inefficient, surgical treatment is required.


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