scholarly journals The role of pleural fluid procalcitonin in the differential diagnosis in parapneumonic pleural effusions and its relation with the ultrasound image of the pleural fluid

2019 ◽  
Author(s):  
Bülent Akkurt
Keyword(s):  
Differential Diagnosis ◽  
Pleural Fluid ◽  
Ultrasound Image ◽  
Pleural Effusions

scholarly journals ROLE OF TUMOR MARKERS IN THE DIAGNOSIS OF MALIGNANT PLEURAL EFFUSIONS

2020 ◽  
pp. 1-2
Author(s):  
Subhakar Kandi ◽  
Ajay Kumar P ◽  
Shravika Reddy Kandi
Keyword(s):  
Differential Diagnosis ◽  
Pleural Fluid ◽  
Tumor Markers ◽  
P Value ◽  
Pleural Effusions ◽  
Malignant Pleural Effusions ◽  
Tuberculous Pleurisy

As an aid in the differential diagnosis of oxidative pleural effusions tumor markers were investigated. We measured carcinoembrionic antigen (CEA) and a glycoprotein CA 15-3 in the pleural fluid of 33 patients with carcinomatous pleural effusions and of ten patients with tuberculous pleurisy and other causes because we have frequently found those diseases to be associated with exudative pleuritis. CEA and CA 15-3 were significantly higher in carcinomatous pleural fluids than in tuberculous fluids (p value of 0.0287), therefore combined assay of CEA and CA 15-3 may be useful in distinguishing pleural effusions due to malignancies from those of tuberculous origin.

The role of pleural fluid thiol/disulphide homoeostasis in the differentiation between transudative and exudative pleural effusions

2021 ◽  
Author(s):  
Nazli Gormeli Kurt ◽  
Servan Gokhan ◽  
Ozcan Erel ◽  
Celal Gunes ◽  
Ahmet Fatih Kahraman ◽  
...  
Keyword(s):  
Pleural Fluid ◽  
Pleural Effusions

scholarly journals The Differential Diagnostic Values of Cytokine Levels in Pleural Effusions

2005 ◽  
Vol 2005 (1) ◽  
pp. 2-8 ◽  
Author(s):  
Saadet Akarsu ◽  
A. Nese Citak Kurt ◽  
Yasar Dogan ◽  
Erdal Yilmaz ◽  
Ahmet Godekmerdan ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Pleural Effusion ◽  
Pleural Fluid ◽  
Parapneumonic Effusion ◽  
Pleural Effusions ◽  
Tuberculous Pleural Effusion ◽  
Cytokine Levels ◽  
Diagnostic Values

The aim is to examine whether the changes in pleural fluid interleukin (IL)-1β, IL-2, IL-6, and IL-8 levels were significant in differential diagnosis of childhood pleural effusions. IL-1β, IL-2, IL-6, and IL-8 levels in pleural fluids of all 36 patients were measured. The levels of IL-1β, IL-2, IL-6, and IL-8 in pleural fluids were statistically significantly higher in the transudate group compared with those of the exudate group. The levels of IL-1β, IL-6, and IL-8 were also found to be statistically significantly higher in the empyema group compared with both the parapneumonic and the tuberculous pleural effusion groups. The levels of IL-2 and IL-6 were detected to be statistically significantly higher in the tuberculous pleural effusion group in comparison with those of the parapneumonic effusion group. The results showed that pleural fluids IL-1β, IL-2, IL-6, and IL-8 could be used in pleural fluids exudate and transudate distinction.

scholarly journals Pleural tuberculosis

2016 ◽  
Vol 65 (1) ◽  
Author(s):  
B. Chakrabarti ◽  
P.D.O. Davies
Keyword(s):  
Pleural Fluid ◽  
Diagnostic Yield ◽  
Western World ◽  
Pleural Effusions ◽  
Pleural Biopsy ◽  
Biopsy Specimens ◽  
Tuberculous Pleurisy ◽  
The Impact ◽  
Antituberculous Chemotherapy

Pleural effusions in tuberculosis are commonly seen in young adults as an immunological phenomenon occurring soon after primary infection. However, the epidemiology and demographics of tuberculous pleurisy are changing due to the impact of HIV co-infection and the increasing number of pleural effusions seen as part of re-activation disease. Pleural biopsy for histology and culture is the mainstay of diagnosis with closed needle biopsy adequate in the majority of cases. Techniques such as PCR of biopsy specimens and the role of pleural fluid ADA are still being evaluated as a diagnostic aid. Tuberculous empyema is less commonly seen in the western world and the diagnostic yield from pleural fluid here is greater than in “primary” effusions. Treatment with appropriate antituberculous chemotherapy is generally successful though there is currently insufficient evidence to recommend the routine use of corticosteroids in this condition.

scholarly journals Role of Combined Pleural Fluid Cholesterol and Total Protein in Differentiation of Exudates and Transudates

2020 ◽  
Vol 3 (1) ◽  
pp. 282-285
Author(s):  
Anupam Bista ◽  
Suman Thapa ◽  
Prasant Subedi ◽  
Kiran Manandhar
Keyword(s):  
Pleural Fluid ◽  
Standard Method ◽  
Total Protein ◽  
Gold Standard ◽  
Pleural Effusions

Introduction: Light's criteria had been the standard method for distinguishing exudative and transudative pleural effusions which misidentify 15-20% of transudates as exudates. This study aims to find out the role of combined pleural fluid cholesterol and total protein in distinguishing exudative from transudative pleural effusions and its applicability in Nepalese populations. Materials and Methods: Patients with pleural effusions were enrolled for the study. The combined pleural fluid cholesterol and total protein were compared with Light’s criteria and also compared with the diagnosis on discharge to find out their usefulness in categorizing the pleural effusions. Results: A total of 81 patients enrolled in the study, 42 (51.9%) were male. Based on Light’s criteria, 88.8% pleural effusions were found to be exudates and 11.1% were found to be transudates. Within the criteria, Light’s criteria categorized more pleural fluids as exudates than the diagnosis on discharge. Based on pleural fluid cholesterol >60mg/dL and protein >3g/dL for the classification of exudative and transudative pleural fluid, 62.9% out of 81 samples felled under the exudates and 37.03% pleural effusions under transudates with the sensitivity 87.9% and specificity 100%. Conclusions: Though Light’s criteria remain the gold standard to differentiate transudates and exudates, combined pleural fluid cholesterol and total protein give nearly comparable results without the need for simultaneous blood investigations.

scholarly journals Role of Pleural Fluid Albumin in the Exudative Pleural Effusions

CHEST Journal ◽  
2010 ◽  
Vol 138 (4) ◽  
pp. 341A
Author(s):  
Seok-Chul Yang ◽  
Chang-Hoon Lee ◽  
Ho Il Yoon ◽  
Sang-Min Lee ◽  
Jae-Joon Yim ◽  
...  
Keyword(s):  
Pleural Fluid ◽  
Pleural Effusions

scholarly journals Pleural Fluid Echogenicity Measured by Ultrasound Image Pixel Density to Differentiate Transudative vs. Exudative Pleural Effusions

2022 ◽  
Author(s):  
Nilam J Soni ◽  
Zachary S Dreyfuss ◽  
Shane Ali ◽  
Austin Enenmoh ◽  
Kevin C Proud ◽  
...  
Keyword(s):  
Pleural Fluid ◽  
Ultrasound Image ◽  
Pleural Effusions

scholarly journals Combined analysis of C-reactive protein in pleural fluid and serum is effective in the differential diagnosis of exudative pleural effusions

2021 ◽  
Vol 9 (14) ◽  
pp. 1183-1183
Author(s):  
Shuo-Yao Qu ◽  
Yong Zhang ◽  
Shuo Wu ◽  
Ming-Ming Wang ◽  
Ling-Li Liu ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Pleural Fluid ◽  
Pleural Effusions ◽  
C Reactive Protein ◽  
Combined Analysis ◽  
Reactive Protein

Pleural fluid mesothelin for the differential diagnosis of exudative pleural effusions

2009 ◽  
Vol 133 (12) ◽  
pp. 449-453 ◽  
Author(s):  
Carmen Alemán ◽  
José Manuel Porcel ◽  
Rosa Ma Segura ◽  
José Alegre ◽  
Aureli Esquerda ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Pleural Fluid ◽  
Pleural Effusions

scholarly journals Potential diagnostic value of pleural fluid cytokines levels for tuberculous pleural effusion

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Neda Dalil Roofchayee ◽  
Majid Marjani ◽  
Neda K. Dezfuli ◽  
Payam Tabarsi ◽  
Afshin Moniri ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Pleural Effusion ◽  
Diagnostic Accuracy ◽  
Pleural Fluid ◽  
Diagnostic Value ◽  
Parapneumonic Effusion ◽  
Pleural Effusions ◽  
Tuberculous Pleural Effusion ◽  
New Biomarkers ◽  
High Level

AbstractPatients with tuberculous pleural effusion (TPE) or malignant pleural effusions (MPE) frequently have similar pleural fluid profiles. New biomarkers for the differential diagnosis of TPE are required. We determined whether cytokine profiles in the PE of patients could aid the differential diagnosis of TPE. 30 patients with TPE, 30 patients with MPE, 14 patients with empyema (EMP) and 14 patients with parapneumonic effusion (PPE) were enrolled between Dec 2018 and 2019. The levels of interleukin (IL)-6, IL-18, IL-27, CXCL8, CCL-1 and IP-10 were determined in PE by ELISA along with measurements of adenosine deaminase (ADA). The best predictors of TPE were combined ADA.IL-27 [optimal cut-off value = 42.68 (103 U ng/l2), sensitivity 100%, specificity 98.28%], ADA [cut off value 27.5 (IU/l), sensitivity 90%, specificity 96.5%] and IL-27 [cut-off value = 2363 (pg/ml), sensitivity 96.7%, specificity 98.3%, p ≤ 0.0001]. A high level of IL-6 [cut-off value = 3260 (pg/ml), sensitivity 100%, specificity 67.2%], CXCL8 [cut-off value = 144.5 (pg/ml), sensitivity 93.3%, specificity 58.6%], CCL1 [cut-off value = 54 (pg/ml), sensitivity 100%, specificity 70.7%] and IP-10 [cut-off value = 891.9 (pg/ml), sensitivity 83.3%, specificity 48.3%] were also predictive of TPE. High ADA.IL-27, ADA and IL-27 levels differentiate between TPE and non-TPE with improved specificity and diagnostic accuracy and may be useful clinically.

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