scholarly journals External Quality Control in the Determination of Neonatal Bilirubin. An Approach to the Improvement of Results

1988 ◽  
Vol 26 (7) ◽  
Author(s):  
G. Röhle ◽  
H. Schlebusch ◽  
W. J. Geilenkeuser ◽  
R. Kruse
Keyword(s):  
Quality Control ◽  
External Quality Control ◽  
External Quality

Comparison of three commercial assays for the measurement of 17α-hydroxyprogesterone (17α-OHPR): limitations of the quality control system

2004 ◽  
Vol 42 (4) ◽  
Author(s):  
Ursula Meier ◽  
Claudia Schnabel ◽  
Dagmar Kunz ◽  
Reinhard Driesch ◽  
Axel M. Gressner
Keyword(s):  
Quality Control ◽  
Moving Average ◽  
External Quality Control ◽  
Acth Stimulation ◽  
Hydroxylase Deficiency ◽  
External Quality ◽  
Stimulation Tests ◽  
21 Hydroxylase Deficiency

AbstractThe measurement of 17α-hydroxyprogesterone (17α-OHPR) is of value for the diagnosis and management of congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency. In the central laboratory from 2000 to 2002, we observed, using the assay from the manufacturer DSL, an elevation of the moving average of 17α-OHPR concentrations and a number of adrenocorticotropic hormone (ACTH) stimulation tests despite the lack of any changes to the internal and external quality control, of which the criteria were continuously fulfilled. We studied a population of n=49 patients for the measurement of 17α-OHPR, with and without extraction, to evaluate the quality of different commercially available radioimmunoassays. The internal and external quality controls were successful in determining 17α-OHPR. An excellent measurement and correlation of 17α-OHPR was expressed with the assay from the manufacturer IBL without extraction and from the manufacturer DSL with extraction. The quantitative determination of 17α-OHPR requires adequate specificity and accuracy of the 17α-OHPR radioimmunoassays. The results show that internal and external quality control systems are not sufficient to resolve analytical problems described in this study.

scholarly journals The Schemes of External Quality Control in Laboratory Medicine in the Balkans

2007 ◽  
Vol 26 (3) ◽  
pp. 245-247
Author(s):  
Petros Karkalousos
Keyword(s):  
Quality Control ◽  
Scientific Community ◽  
Clinical Chemistry ◽  
Laboratory Medicine ◽  
External Quality Control ◽  
External Quality ◽  
The Balkans ◽  
Control Schemes ◽  
Balkan Countries ◽  
Balkan Region

The Schemes of External Quality Control in Laboratory Medicine in the Balkans There are many differences between the national External Quality Control Schemes all around Europe, but the most important ones are certainly those between the countries of the Balkan region. These differences are due to these countries' different political and financial development, as well as to their tradition and the development of clinical chemistry science in each one. Therefore, there are Balkan countries with very developed EQAS and others where there is no such a scheme. Undoubtedly, the scientific community in these countries wants to develop EQAS despite of the financial and other difficulties.

Assessment of the correctness of identification and determination of antimicrobial susceptibility of Streptococcus pneumoniae in microbiological laboratories in Poland

2020 ◽  
Vol 55 (4) ◽  
pp. 271-276
Author(s):  
Ewa Młodzińska ◽  
Waleria Hryniewicz
Keyword(s):  
Quality Control ◽  
Antimicrobial Susceptibility ◽  
Bacterial Resistance ◽  
External Quality Assessment ◽  
Resistance Mechanisms ◽  
Medical Problems ◽  
External Quality ◽  
External Quality Assessment Scheme ◽  
Reliable Identification

The increase in bacterial resistance to antimicrobials is one of the most serious medical problems, therefore reliable identification in microbiological laboratories is important. The Polish National External Quality Assessment Scheme in Microbiological Diagnostics – POLMICRO programme is organized by the Centre of Quality Control in Microbiology (CQCM) enables the assessment of the competence of Polish microbiological laboratories in the field of identification, determination of susceptibility and detection of drug resistance mechanisms. This work presents the assessment of the results of identification and determination of S. pneumoniae antimicrobial susceptibility obtained by Polish laboratories during the 20 years of experience of the POLMICRO programme.

scholarly journals Necessity of External Quality Control for anti-Mycoplasma pneumoniae IgM antibodies

2008 ◽  
Vol 23 (2) ◽  
Author(s):  
Massimo De Paschale ◽  
Luisa Belvisi ◽  
Debora Cagnin ◽  
Teresa Cerulli ◽  
Maria Teresa Manco ◽  
...  
Keyword(s):  
Quality Control ◽  
Mycoplasma Pneumoniae ◽  
External Quality Control ◽  
External Quality ◽  
Igm Antibodies

scholarly journals External Quality Assessment in the Evaluation of Laboratory Performance of Faecal Culture

2017 ◽  
Vol 10 ◽  
pp. 117863611769125
Author(s):  
Salla J Kiiskinen ◽  
Tarja Ojanen ◽  
Yvonne Björkman ◽  
Harri Laitinen ◽  
Anja Siitonen
Keyword(s):  
Public Health ◽  
Quality Control ◽  
External Quality Assessment ◽  
False Negative ◽  
The Other ◽  
Epidemiological Surveillance ◽  
External Quality Control ◽  
External Quality ◽  
Faecal Culture

In Finland, all laboratories carrying out diagnostics of infectious diseases in humans are approved by the Regional State Administrative Agencies and are obligated to participate in External Quality Assurance rounds. Performance in these rounds is thought to reflect the quality of laboratory work. In the 6-year study period, 17 Finnish laboratories received 48 simulated faecal specimens for the culturing of diarrhoeal pathogens, yielding altogether 586 faecal culture External Quality Control specimens and 581 reports. The results were correct in 92% of all reports and in 67% of all specimens. False-negative Salmonella results were given for 2 of the 18 specimens, one with biochemically atypical Salmonella strain and the other with a low count of Salmonella cells. False-negative Shigella report was given for 6 of the 7 specimens in some participating laboratory. Detection of all common faecal pathogens is especially relevant to patient safety, public health, and epidemiological surveillance.

scholarly journals Paracetamol: A Report of a Regional Quality Control Scheme

1979 ◽  
Vol 16 (1-6) ◽  
pp. 265-270 ◽  
Author(s):  
J. Epton
Keyword(s):  
Quality Control ◽  
Group Performance ◽  
Clinical Importance ◽  
External Quality Control ◽  
External Quality ◽  
Limits Of Detection ◽  
Trouble Shooting ◽  
Control Scheme ◽  
Considerable Impact ◽  
Quality Control Scheme

The results from an external quality control scheme for the assay of paracetamol in serum are reported. A preferential method of assay has not become evident, but, as a result of the scheme, some laboratories have changed or modified their techniques or have re-established the limits of detection. The majority of laboratories were able to estimate paracetamol satisfactorily at those levels which are of clinical importance. The overall group performance has shown little change. The programme has had considerable impact in so far as it has led to a mutually useful interchange of information and trouble shooting.

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