scholarly journals Pharmacogenetics of drug-metabolizing enzymes in US Hispanics

Author(s):  
Karla Claudio-Campos ◽  
Jorge Duconge ◽  
Carmen L. Cadilla ◽  
Gualberto Ruaño

AbstractAlthough the Hispanic population is continuously growing in the United States, they are underrepresented in pharmacogenetic studies. This review addresses the need for compiling available pharmacogenetic data in US Hispanics, discussing the prevalence of clinically relevant polymorphisms in pharmacogenes encoding for drug-metabolizing enzymes.

1990 ◽  
Vol 85 (411) ◽  
pp. 902
Author(s):  
Lisandro Perez ◽  
Frank D. Bean ◽  
Marta Tienda

2011 ◽  
Vol 21 (3) ◽  
pp. 281-285 ◽  
Author(s):  
William N. Evans ◽  
Ruben J. Acherman ◽  
William J. Castillo ◽  
Humberto Restrepo

AbstractWe analysed the occurrence of tetralogy of Fallot and simple transposition in the Hispanic and non-Hispanic populations of Clark County, Nevada, in the United States of America over a 30-year period from 1980 to 2009. We found a downward trend in the incidence of simple transposition of the great arteries in the non-Hispanic population but an upward trend in the incidence in the Hispanic population. For tetralogy of Fallot, we found an upward trend in the incidence in both populations; the trend, however, was more dramatic in the Hispanic population. We also noted differences in the male to female ratios in the different groups. Even though we make no definitive conclusions regarding the causes of these incidence curves or the differences in occurrence between males or females, the data suggest an interplay of genetics and the environment.


2011 ◽  
Vol 9 (10) ◽  
pp. 834-841 ◽  
Author(s):  
Andres F. Carrion ◽  
Ravi Ghanta ◽  
Olveen Carrasquillo ◽  
Paul Martin

1998 ◽  
Vol 63 (6) ◽  
pp. 623-628 ◽  
Author(s):  
Carmen Martínez ◽  
José A. G. Agúndez ◽  
Manuela Olivera ◽  
Adrián LLerena ◽  
Ronald Ramirez ◽  
...  

2021 ◽  
pp. mcs.a005967
Author(s):  
Alfonso E. Bencomo-Alvarez ◽  
Andres J. Rubio ◽  
Mayra A. Gonzalez ◽  
Anna M. Eiring

2021 ◽  
pp. 0739456X2110536
Author(s):  
C. J. Gabbe ◽  
Gregory Pierce ◽  
Emily Petermann ◽  
Ally Marecek

Heat is the deadliest weather-related hazard in the United States. This paper studies municipal heat adaptation using survey and planning data from California. We first analyze the characteristics of municipalities that innovate. Cities with heat-related policies have greater degrees of projected extreme heat, leadership support, environmental justice planning, and smaller Hispanic population shares. We then assess specific policy innovations of six large cities by plan type. Some strategies, including expanding tree canopies, have been widely adopted while others, such as cool walls, are rarely included. Findings suggest that planners can—and should—play a central role in heat adaptation planning.


2022 ◽  
pp. 136346152110381
Author(s):  
Michael J. Zvolensky ◽  
Andrew H. Rogers ◽  
Nubia A. Mayorga ◽  
Justin M. Shepherd ◽  
Jafar Bakhshaie ◽  
...  

The Hispanic population is the largest minority group in the United States and frequently experiences racial discrimination and mental health difficulties. Prior work suggests that perceived racial discrimination is a significant risk factor for poorer mental health among Hispanic in the United States. However, little work has investigated how perceived racial discrimination relates to anxiety and depression among Hispanic adults. Thus, the current study evaluated the explanatory role of experiential avoidance in the relation between perceived racial discrimination and anxiety/depressive symptoms and disorders among Hispanic adults in primary care. Participants included 202 Spanish-speaking adults ( Mage = 38.99, SD = 12.43, 86.1% female) attending a community-based Federally Qualified Health Center. Results were consistent with the hypothesis that perceived racial discrimination had a significant indirect effect on depression, social anxiety, and anxious arousal symptoms as well as the number of mood and anxiety disorders through experiential avoidance. These findings suggest future work should continue to explore experiential avoidance in the association between perceived racial discrimination and other psychiatric and medical problems among the Hispanic population.


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