Severe hypertriglyceridemia at new onset type 1 diabetes mellitus

2017 ◽  
Vol 30 (8) ◽  
Author(s):  
Tyler Fick ◽  
Julie Jack ◽  
Amy L. Pyle-Eilola ◽  
Rohan K. Henry
Keyword(s):  
Type 1 Diabetes ◽  
Pediatric Population ◽  
Rare Complication ◽  
Venous Blood ◽  
Laboratory Data ◽  
Clinical Criteria ◽  
Severe Hypertriglyceridemia ◽  
Venous Blood Gas ◽  
New Onset

AbstractBackground:Severe hypertriglyceridemia (HTG) as well as diabetic ketoacidosis (DKA) are complications of type 1 diabetes (T1DM). HTG is an exceedingly rare complication in the pediatric population and herein we report a case of HTG at new-onset T1DM in DKA and discuss management and potential complications.Case presentation:An 11-year-old previously well patient with a history of fatigue and weight loss presented with: glucose >600 mg/dL, venous blood gas: pH 7.26, pCOConclusions:Lipemia secondary to severe HTG, though exceedingly rare, may exist in new onset T1DM with DKA. Complicating the diagnosis is the possibility of an analytical error from lipemia causing incongruence in diagnostic criteria. Clinicians should rely on clinical criteria for management and should consider HTG if laboratory data is inconsistent with the clinical picture.

scholarly journals Severe Hypertriglyceridemia With New-Onset Type 1 Diabetes in Diabetic Ketoacidosis

2020 ◽  
Vol 11 (12) ◽  
pp. 426-428
Author(s):  
Baninder Kaur Baidwan ◽  
Elizabeth T. Walsh ◽  
Joseph A. Skelton ◽  
Cathrine Constantacos ◽  
Janel D. Hunter ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Diabetic Ketoacidosis ◽  
Onset Type ◽  
Severe Hypertriglyceridemia ◽  
New Onset

Infantile cerebral infarction caused by severe diabetic ketoacidosis in new-onset type 1 diabetes mellitus

2019 ◽  
Vol 32 (12) ◽  
pp. 1391-1394
Author(s):  
Junichi Suzuki ◽  
Tatsuo Fuchigami ◽  
Kengo Kawamura ◽  
Masako Aoki ◽  
Tatsuhiko Urakami ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Cerebral Infarction ◽  
Type 1 Diabetes Mellitus ◽  
Diabetic Ketoacidosis ◽  
Cerebral Edema ◽  
Rare Complication ◽  
Case Presentation ◽  
New Onset

Abstract Background Diabetic ketoacidosis (DKA) is a common complication of type 1 diabetes mellitus (T1DM). Infants and children with new-onset T1DM may present with DKA, and the risk of cerebral edema is high in infantile DKA. What is new? Neurological deterioration during an episode of DKA is usually attributed to cerebral edema and cerebrovascular accidents. However, cerebral infarction is a very rare complication in infantile DKA. Case presentation We describe a rare case of infantile cerebral infarction caused by severe DKA in a patient with new-onset T1DM. Conclusions Cerebral infarction is an important intracranial complication in infantile DKA. Careful observation and treatment for DKA during the first 24 h of therapy are necessary in infants with new-onset T1DM because the risk of cerebral infarction is highest during this timeframe.

scholarly journals Missing during COVID-19 lockdown: children with new-onset type 1 diabetes

2020 ◽  
Author(s):  
Devi Dayal ◽  
Saniya Gupta ◽  
Dhvani Raithatha ◽  
Muralidharan Jayashree
Keyword(s):  
At Risk ◽  
Type 1 Diabetes ◽  
Pediatric Population ◽  
Middle Income ◽  
Onset Type ◽  
Middle Income Countries ◽  
Healthcare Settings ◽  
The Impact ◽  
New Onset

Abstract The redistribution of healthcare resources for coronavirus 2019 (COVID-19) pandemic has resulted in unintentional neglect of essential non-COVID-19 care (1). In low- and lower-middle income countries (LMIC), the already overstretched healthcare systems have crumbled under the COVID-19 pressure (2). Additionally, hardline lockdown restrictions, and fear of exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in healthcare settings have forced patients with non-COVID-19 illnesses to stay home and suffer until their illness deteriorates substantially, and sometimes irreversibly. The impact of COVID-19 on the pediatric population has so far been mild, except in children with comorbidities (3). However, children who develop new time-sensitive non-COVID-19 illnesses during the pandemic are at risk of worsening or death due to compromised access to hospital care. In particular, children with new-onset type 1 diabetes (T1D) may progress rapidly to diabetic ketoacidosis (DKA) if treatment with insulin is delayed, and are therefore at risk of increased morbidity and mortality.

Newly diagnosed type 1 diabetes in a 93 year old

2022 ◽  
Vol 15 (1) ◽  
pp. e246799
Author(s):  
Waqar Ahmad ◽  
Catherine Bates ◽  
Laura Dale ◽  
Naveen Siddaramaiah
Keyword(s):  
Type 1 Diabetes ◽  
Venous Blood ◽  
Primary Hypothyroidism ◽  
Intravenous Insulin ◽  
Parietal Cell Antibodies ◽  
High Clinical Suspicion ◽  
History Of ◽  
Laboratory Investigations ◽  
Venous Blood Gas

Type 1 diabetes is typically a disease of young but can present at any age. We present a case of a 93-year-old woman who presented with 10 days history of feeling lethargic, polydipsia and decreased appetite. Her capillary blood glucose was raised at 25 mmol/L with significant ketonaemia and venous blood gas showing metabolic acidosis. She had a background of primary hypothyroidism and vitamin B12 deficiency with weakly positive parietal cell antibodies. Laboratory investigations confirmed diabetes with HbA1c of 117 mmol/mol (12.9%). In view of high clinical suspicion of type 1 diabetes, her diabetes autoantibodies were checked which showed strongly positive anti-GAD antibody with titre of >2000 IU/mL (range<10) confirming our diagnosis. She was treated with diabetic ketoacidosis protocol with intravenous fluids and intravenous insulin. On recovery, she was discharged home on once daily insulin with aim to self-manage diabetes with support from district nurses and to avoid hypoglycaemia.

1290-P: Gut Microbiota in New-Onset Pediatric Patients with Type 1 Diabetes: Machine Learning Algorithms to Classify Microorganisms Disease-Linked

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1290-P
Author(s):  
GIUSEPPE D’ANNUNZIO ◽  
ROBERTO BIASSONI ◽  
MARGHERITA SQUILLARIO ◽  
ELISABETTA UGOLOTTI ◽  
ANNALISA BARLA ◽  
...  
Keyword(s):  
Machine Learning ◽  
Type 1 Diabetes ◽  
Gut Microbiota ◽  
Pediatric Patients ◽  
Learning Algorithms ◽  
Machine Learning Algorithms ◽  
New Onset

16-OR: Codesigning an Intervention for Adults with New-Onset Type 1 Diabetes to Improve Psychological and Social Adaptation

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 16-OR
Author(s):  
METTE DUE-CHRISTENSEN ◽  
LENE E. JOENSEN ◽  
SOPHIE SARRE ◽  
JULIE L. WAD ◽  
EWA ROMANCZUK ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Social Adaptation ◽  
Onset Type ◽  
New Onset
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