Synthesis and characterization of PCU@C-Ag/AgCl nanoparticles as an antimicrobial material for respiratory tract infection

2021 ◽  
Vol 6 (1) ◽  
pp. 68-78
Author(s):  
Senthilkumar Palanisamy ◽  
Kalaivani Subramanian ◽  
Lerince Godrina Bennet ◽  
Janani Ambrose ◽  
Aganiya Gopalakrishnan ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Antimicrobial Agents ◽  
Morphological Changes ◽  
Visible Spectrum ◽  
Ag Nps ◽  
Antimicrobial Material ◽  
Agcl Nanoparticles

Abstract The pregnant cow urine (PCU) is an active source of antimicrobial agents that is used for fabricating chitosan coated Ag/AgCl nanoparticles (NPs) in the present study. These PCU@C-Ag/AgCl NPs were physicochemically characterized and evaluated for antimicrobial activity against selected respiratory tract infection (RTI) pathogens. The absorption band around 420 nm in UV-Visible spectrum indicated the presence of Ag NPs. The spherical shape of NPs was observed using TEM. Also, the crystalline structure was confirmed using the XRD pattern. The PCU@C-Ag/AgCl NPs showed strong antimicrobial activity against all tested RTI pathogens. In addition, FESEM analysis showed morphological changes in RTI bacterial pathogens. Thereby, PCU@C-Ag/AgCl NPs may be used as an antimicrobial material to treat RTIs in near future at clinical level.

Resistance of Haemophilus influenzae Isolates in Children Under 5 Years Old with Acute Respiratory Infections in China between 2000 and 2002

2007 ◽  
Vol 35 (4) ◽  
pp. 554-563 ◽  
Author(s):  
XZ Shen ◽  
Q Lu ◽  
L Deng ◽  
S Yu ◽  
H Zhang ◽  
...  
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Haemophilus Influenzae ◽  
Respiratory Tract Infection ◽  
Antimicrobial Agents ◽  
Upper Respiratory Tract Infection ◽  
Chinese Children ◽  
Upper Respiratory Tract ◽  
Ampicillin Resistance ◽  
Upper Respiratory

This prospective, three-centre study tested for antimicrobial susceptibility in 898 isolates of Haemophilus influenzae between 2000 and 2002 in Chinese children aged under 5 years with acute upper respiratory tract infection. The average incidence of β-lactamase production was 12.0%. Overall, 88.0% of isolates were susceptible to ampicillin, 100.0% were susceptible to amoxicillin/clavulanic acid, ceftriaxone, cefuroxime and azithromycin, and 99.0% were susceptible to ciprofloxacin. Isolates from Beijing and Shanghai had a lower susceptibility to tetracycline (57.0% and 61.0%, respectively) compared with those from Guangzhou (81.0%), while trimethoprim/sulfamethoxazole susceptibilities in Shanghai (47.0%) and Guangzhou (54.0%) were significantly higher than in Beijing (35.0%). A total of 34.5% of all the isolates were susceptible to all eight of these antimicrobial agents and 12.8% were multi-drug resistant. Ampicillin resistance increased over the duration of the study. These findings show that β-lactamase production and ampicillin resistance among isolates from Chinese children with upper respiratory tract infection are increasing, and highlight the strong correlation between ampicillin resistance and resistance to cefaclor, chloramphenicol and tetracycline in H. influenzae isolates.

scholarly journals New Progress in the Cause Analysis and Nursing of Respiratory Tract Infection after Abdominal Surgery under General Anesthesia

2016 ◽  
Vol 5 (3) ◽  
pp. 75-80
Author(s):  
Congxian Yang
Keyword(s):  
Tract Infection ◽  
Abdominal Surgery ◽  
Respiratory Tract ◽  
General Anesthesia ◽  
Respiratory Tract Infection ◽  
Respiratory Function ◽  
Antimicrobial Agents ◽  
Perioperative Management ◽  
Nursing Intervention ◽  
Cause Analysis

Abstract This article provides a review of the causes of respiratory tract infection after abdominal surgery. These causes include general anesthesia, intubation factors, factors inherent to the patient, surgical factors, the injudicious use of antimicrobial agents, and the environmental factors of the ward. The perioperative management of the respiratory tract should be strengthened. Health education, respiratory function training, oral nursing intervention, atomization inhalation, and personalized expectoration methods should receive more attention to decrease the complications and promote the early rehabilitation of patients after abdominal surgery.

Characteristics of bacterial etiology in lower respiratory tract infection: a surveillance report from a Chinese large teaching hospital from 2015 to 2019

2020 ◽  
Author(s):  
Lei Tian ◽  
Zhongju Chen ◽  
Feng He ◽  
Ziyong Sun
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Lower Respiratory Tract Infection ◽  
Lower Respiratory Tract ◽  
Bacterial Resistance ◽  
Antimicrobial Agents ◽  
Lavage Fluid ◽  
Resistance Rate ◽  
Sputum Culture

Abstract Background: Lower respiratory tract infection (LRI) is a very common clinical disease. The etiological diagnosis of LRI often depends on the result of sputum culture. Sputum is the most common specimen type of LRI in China, but its cultivation result is easily confused by the bacteria colonized in the oral cavity and pharynx. It is very difficult to evaluate the clinical significance of sputum culture results both for clinicians and microbiologists. Fortunately, bronchoscope alveolus lavage fluid(BALF)is a good specimen, whose culture results can accurately reflect the situation of LRI. By analyzing the culture results and antimicrobial agents sensitivity data of BALF accumulated in this area, we can provide reference for clinicians to experience in the treatment of lower respiratory tract infection.Methods: The accumulated data of BALF culture and antimicrobial susceptibility test in our hospital from January 2015 to October 2019 were reviewed and analyzed.Results: The positive rate of BALF culture in our hospital was 18.3% (3467/18935) in 2015-2019. The most common pathogens were Klebsiella pneumoniae (18.1%, 627/3467), Pseudomonas aeruginosa (16.9%, 587/3467) and Acinetobacter baumannii (14.0%, 485/3467). For the eight most common pathogens (K. pneumoniae, P. aeruginosa, A. baumannii, Staphylococcus aureus, Haemophilus influenzae, Stenotrophomonas maltophilia, Escherichia coli and S. pneumoniae), 40-70 years old was the highest age of distribution, but for E. coli and S. pneumoniae, 0-5 years old was also the higher age of distribution. The antibiotic resistance rate of K. pneumoniae to imipenem and meropenem was 30.6% and 30.8%, respectively. The sensitivity of P. aeruginosa to antibiotics other than minocycline and ticarcillin clavulanic acid was all more than 60%. However, the resistance rate of A. baumannii to antibiotics other than tegacyclin and minocycline was all more than 80%.Conclusions: 40-70 years old was the high incidence age of lower respiratory tract bacterial infection. K. pneumoniae resistant to carbapenems (CR-K. pneumoniae) and A. baumannii were a great challenge to clinical treatment and bacterial resistance control.

Antibiotic consumption and susceptibility of isolates in patients with low respiratory tract infection

Pneumologie ◽  
2015 ◽  
Vol 69 (S 01) ◽  
Author(s):  
EJS Hurtado ◽  
MJG Fernández ◽  
AA Arregosa ◽  
JM González Miret ◽  
MZ Rascón ◽  
...  
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Antibiotic Consumption
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