Hypermetabolic Response Induced by Juvenile Hormone Analogues in an Insect
Some synthetic analogues of insect juvenile hormone cause tremendous rise of respiratory metabolism in the last larval instar of Dermestes maculatus. The O2 consumption values occasionally found in these hypermetabolic larvae (20 ml/g/h) can be classified among the most intensive respiratory rates ever recorded in living organisms. The phenomenon is directly related to the dose of juvenile hormone activity and it is dependent on nutrition. The mechanism of such specific metabolic action of juvenile hormone is based on complete oxidation of the dietary fatty acids, providing metabolic water for larval somatic growth. The excessive amounts of energy created by hypermetabolism are partly converted to heat, suggesting uncoupling of phosphorylation. Some other specific endocrmological features associated with hypermetabolism have been discussed.