scholarly journals Long-term body composition improvement in post-menopausal women following bariatric surgery: a cross-sectional and case-control study

2021 ◽  
Author(s):  
Sara Santini ◽  
Nathalie Vionnet ◽  
Jérôme Pasquier ◽  
Michel Suter ◽  
Didier Hans ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Weight Loss ◽  
Body Composition ◽  
Lipid Profile ◽  
Positive Impact ◽  
Case Control ◽  
Cross Sectional ◽  
Menopausal Women ◽  
Post Menopausal

Objective: Bariatric surgery (BS) induces loss of body fat mass (FM) with an inexorable loss of lean mass (LM). Menopause leads to deleterious changes in body composition (BC) related to estrogen deficiency including LM loss and increase in total and visceral adipose tissue (VAT). This study aims to describe long-term weight evolution of post-menopausal women after RYGB (Roux-en-Y gastric bypass) and to compare BC between BS patients versus post-menopausal non-operated women. Design: Cross-sectional study of 60 post-menopausal women who underwent RYGB ≥ two years prior to the study with nested case-control design. Methods: Post-menopausal BS women were matched for age and BMI with controls. Both groups had DXA scan, lipids and glucose metabolism markers assessment. Results: Median follow-up was 7.5(2–18) years. Percentage of total weight loss (TWL%) was 28.5±10%. After RYGB, LM percentage of body weight (LM%) was positively associated with TWL% and negatively associated with nadir weight. Forty-one post-BS women were matched with age- and BMI-controls. Post-BS patients showed higher LM% (57.7%[±8%] versus 52.5%[±5%], p=0.001), reduced FM% (39.4%[±8.4%] versus 45.9%[±5.4%] p<0.01) and lower VAT (750.6g[±496] versus 1295.3g[±688], p<0.01) with no difference in absolute LM compared to controls. While post-BS women showed a better lipid profile compared to controls, no difference was found in glucose markers. Conclusions: Post-menopausal women after RYGB have a lower FM and VAT, preserved LM and a better lipid profile compared to controls. Weight loss after RYGB seems to have a persistent positive impact on metabolic health.

Long-term effect of bariatric surgery on body composition in post-menopausal women

2021 ◽  
Vol 46 ◽  
pp. S562
Author(s):  
S. Santini ◽  
N. Vionnet ◽  
M. Suter ◽  
J. Pasquier ◽  
D. Hans ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Body Composition ◽  
Term Effect ◽  
Long Term Effect ◽  
Menopausal Women ◽  
Post Menopausal

Grazing Behavior Hinders Weight Loss in Long-Term Post Bariatric Surgery: a Cross-Sectional Study

2021 ◽  
Author(s):  
Larissa Cristina Lins Berber ◽  
Mariana Silva Melendez-Araújo ◽  
Eduardo Yoshio Nakano ◽  
Kênia Mara Baiocchi de Carvalho ◽  
Eliane Said Dutra
Keyword(s):  
Bariatric Surgery ◽  
Weight Loss ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Grazing Behavior ◽  
Post Bariatric Surgery

scholarly journals Snoring is associated with body composition in （peri-post）menopausal women

2019 ◽  
Author(s):  
minfang tao ◽  
yang zhou ◽  
fei liu ◽  
changbin li ◽  
yanwei zheng ◽  
...  
Keyword(s):  
Body Composition ◽  
Fat Mass ◽  
Chinese Women ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
Menopausal Transition ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
Menopausal Women ◽  
Post Menopausal

Abstract Background: Little attention has been paid to whether snoring frequency is associated with body composition in menopausal women, particularly in China. This study objected to investigate the association between self-reported snoring and body composition in (peri-post) menopausal Chinese women as well as glucose/lipid metabolic indicators. Methods: This cross-sectional study enrolled 715 participants aged 40-67 years from the Menopause Clinic in the Shanghai Sixth People’s Hospital. Participants were categorized into four subgroups stratified by self-reported snoring frequency: never, rarely (<1 night per week), occasionally (1-2 nights per week), regularly (≥3 nights per week), while body composition was measured using bioelectrical impedance analysis(BIA).Besides, blood sample were collected to test the glycolipid indicators. Results: In our sample of investigation, regular snoring (≥3 nights per week) was found to be an independent risk factor for higher fat mass (total, upper limbs, trunk), with the highest risk of 2.4 times for fat mass of trunk after adjusting for glucose/lipid metabolic confounders(p=0.003). Meanwhile, regular snoring was independently associated with higher fat mass (total and each segment) only in the menopausal transition (p=0.023). Conclusion: We suggested that self-reported regular snoring may be taken as a simple alternative to predict higher fat mass (≥17.11kg, upper quartile) in menopausal women. Similarly, body composition should be attached to the great importance to those who in menopausal transition in order to help to prevent obstructive sleep apnea(OSA).

scholarly journals Pengaruh Terapi Gizi Klinik Intensif Terhadap Penurunan Berat Badan, Komposisi Tubuh, dan Profil Lipid pada Remaja Overweight dan Obesitas

2019 ◽  
Vol 7 (1) ◽  
pp. 88-95
Author(s):  
Rita Halim ◽  
Raihanah Suzan ◽  
Maria Estela Karolina
Keyword(s):  
Weight Loss ◽  
Body Composition ◽  
Lipid Profile ◽  
Age Groups ◽  
Nutrition Therapy ◽  
Nutritional Intervention ◽  
Case Control ◽  
Obese Adolescents ◽  
Significant Difference ◽  
Before And After

ABSTRACT Background: Current nutritional status issues are no longer focused on malnutrition, but also on excess nutrition that can occur in all age groups, especially vulnerable to occur at a young age. Objective: to assess the effect of intensive clinical nutrition therapy on weight loss, body composition and lipid profile in overweight and obese adolescents. Method: This study was a case control study and was carried out during the months of August - September 2018, where the sample of the study would be antopometric examination, body composition and lipid profile before and after the intervention. Results: there was no significant difference in the effect of intervention between intensive nutrition therapy compared to only nutrition counseling in weight loss, body composition, and lipid profile. Conclusion: Nutritional intervention in the form of intensive nutrition therapy and counseling conducted in this study had significant results in weight loss, lipid profile and body composition in overweight and obese adolescents, although no significant effect was found on the two interventions. Keywords: Nutritional intervention, weight loss, body compotition, lipid profile, overweight, obesitas   ABSTRAK Latar belakang: Permasalahan status gizi saat ini bukan lagi hanya terpusat pada kekurangan gizi saja, namun juga pada kelebihan gizi yang dapat terjadi pada semua golongan usia, terutama rentan terjadi pada usia muda. Tujuan: menilai pengaruh terapi gizi klinik intensif terhadap penurunan berat badan, komposisi tubuh dan profil lipid pada remaja overweight dan obesitas. Metode: Penelitian ini merupakan penelitian case control dan dilakukan selama bulan Agustus – September 2018, dimana sampel penelitian akan dilakukan pemeriksaan antopometri, komposisi tubuh dan profil lipid sebelum dan sesudah intervensi. Hasil: tidak terdapat perbedaan pengaruh intervensi secara bermakna antara terapi gizi intensif dibandingkan dengan hanya penyuluhan gizi saja dalam menurunkan berat badan, komposisi tubuh, dan profil lipid. Kesimpulan : intervensi gizi berupa terapi gizi intensif dan penyuluhan yang dilakukan pada penelitian ini memiliki hasil yang bermakna terhadap penurunan berat badan, profil lipid dan komposisi tubuh pada remaja overweight dan obesitas walaupun tidak ditemukan perbedaan yang bermakna dari kedua intervensi tersebut. Kata Kunci: intervensi gizi, penurunan berat badan, komposisi tubuh, profil lipid, overweight, obesitas

Effect of bariatric surgery on breast tissue and biomarkers in obese women at increased risk for breast cancer.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. TPS1592-TPS1592
Author(s):  
Tarah Jean Ballinger ◽  
Kathy Miller ◽  
Kandice Ludwig ◽  
Sunil S. Badve ◽  
Don Selzer ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Insulin Resistance ◽  
Bariatric Surgery ◽  
Weight Loss ◽  
Breast Cancer Risk ◽  
Breast Tissue ◽  
Obese Women ◽  
Increased Risk ◽  
Menopausal Women ◽  
Post Menopausal

TPS1592 Background: Obesity represents a challenging epidemic associated with increased risk of several malignancies, including breast cancer in post-menopausal women. Proposed mechanisms for the association between obesity and breast cancer risk include increased insulin resistance, elevated levels of circulating estrogens, and chronic inflammation. Intentional weight loss from bariatric surgery has been associated with decreased risk of breast cancer. While rapid improvements in serologic markers of metabolism and inflammation are seen following bariatric surgery, short- and long- term changes in breast tissue remain less clear. This study investigates the effect of bariatric surgery on breast density and biomarkers of increased risk in breast tissue. Methods: This pilot, single institution, observational study (NCT02681120) is recruiting pre- and post-menopausal women with BMI ≥30 from a University bariatric surgery clinic using the Hughes risk application as a screening tool. Eligible patients must have a lifetime risk for breast cancer of ≥20%. Participants are evaluated by imaging, breast biopsy, and blood samples at baseline, 14 days post-operatively to determine the effects of rapid metabolic changes, and 1 year post-operatively to determine the effects of significant weight loss. The impact of bariatric surgery on known imaging parameters of breast cancer risk is assessed by background parenchymal enhancement on MRI and breast density on mammogram. Breast tissue is evaluated for changes in immune infiltrates, aromatase expression, and the presence of crown-like structures, a marker of inflammation seen in the breast tissue of obese women. Tissue samples at each time point are also compared to samples from lean women in the Susan G. Komen Tissue Bank at the IU Simon Cancer Center. Blood is collected for correlative studies evaluating markers of inflammation, insulin resistance, metabolism, and hormone synthesis. Enrollment is currently ongoing with a planned accrual of 40 patients, and data collection is estimated to complete by the end of 2018. Clinical trial information: NCT02681120.

scholarly journals Bariatric Surgery for Hypothalamic Obesity in Craniopharyngioma Patients: A Retrospective, Matched Case-Control Study

2021 ◽  
Author(s):  
Selveta S van Santen ◽  
Peter Wolf ◽  
Natalia Kremenevski ◽  
Cesar L Boguszewski ◽  
Hannes Beiglböck ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Weight Loss ◽  
Gastric Bypass ◽  
Sleeve Gastrectomy ◽  
Case Control Study ◽  
Case Control ◽  
Hypothalamic Obesity ◽  
Control Study

Abstract Context Craniopharyngioma is a sellar tumor associated with high rates of pituitary deficiencies (~98%) and hypothalamic obesity (~50%). Objective To determine the efficacy regarding long-term weight loss after bariatric surgery in obese craniopharyngioma patients with hypothalamic dysfunction. Design Retrospective case control study. Setting Multicenter international study. Patients and participants Obese craniopharyngioma patients (N = 16; of which 12 women) with a history of bariatric surgery [12 Roux-en-Y gastric bypass, 4 sleeve gastrectomy; median age of 21 years (range 15-52), median follow-up 5.2 years (range 2.0-11.3)] and age/sex/surgery/BMI-matched obese controls (N = 155). Main outcome measures Weight loss and obesity-related comorbidities up to 5 years after bariatric surgery were compared and changes in hormonal replacement therapy evaluated. Results Mean weight loss at 5-year follow-up was 22.0% (95% CI 16.1, 27.8) in patients versus 29.5% (28.0, 30.9) in controls (P = 0.02), which was less after Roux-en-Y gastric bypass (22.7% [16.9, 28.5] vs. 32.0% [30.4, 33.6]; P = 0.003) but at a similar level after sleeve gastrectomy (21.7% [–1.8, 45.2] vs. 21.8% [18.2, 25.5]; P = 0.96). No major changes in endocrine replacement therapy were observed after surgery. One patient died (unknown cause). One patient had long-term absorptive problems. Conclusions Obese patients with craniopharyngioma had a substantial mean weight loss of 22% at 5-year follow-up after bariatric surgery, independent of type of bariatric surgery procedure. Weight loss was lower than in obese controls after Roux-en-Y gastric bypass. Bariatric surgery appears effective and relatively safe in the treatment of obese craniopharyngioma patients.

scholarly journals Association of snoring and body compostion in （peri-post）menopausal women

2020 ◽  
Author(s):  
Minfang Tao ◽  
Yang Zhou ◽  
Fei Liu ◽  
Changbin Li ◽  
Yanwei Zheng ◽  
...  
Keyword(s):  
Body Composition ◽  
Fat Mass ◽  
Chinese Women ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
Menopausal Transition ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
Menopausal Women ◽  
Post Menopausal

Abstract Background: Little attention has been paid to whether snoring frequency is associated with body composition in menopausal women, particularly in China. This study objected to investigate the association between self-reported snoring and body composition in (peri-post) menopausal Chinese women as well as metabolic indicators.Methods: This cross-sectional study enrolled 715 participants aged 40-67 years from the Menopause Clinic in the Shanghai Sixth People’s Hospital. Participants were categorized into four subgroups stratified by self-reported snoring frequency: never, rarely (<1 night per week), occasionally (1-2 nights per week), regularly (≥3 nights per week), while body composition was measured using bioelectrical impedance analysis (BIA).Besides, blood sample were collected to test the glycolipid indicators. Results: In our sample of investigation, regular snoring (≥3 nights per week) was found to be an independent risk factor for higher fat mass (total, upper limbs, trunk), with the highest risk of 2.4 times for fat mass of trunk after adjusting for metabolic confounders(p=0.003). Meanwhile, regular snoring was independently associated with higher fat mass (total and each segment) only in menopausal transition (p=0.023).Conclusions: We suggested that self-reported regular snoring may be taken as a simple alternative to predict higher fat mass (≥17.11kg, upper quartile) in menopausal women. Similarly, body composition should be attached to the great importance to those who in menopausal transition in order to help to prevent obstructive sleep apnea (OSA).

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