scholarly journals Plonos adatos aspiracinė biopsija diagnozuojant skydliaukės vėžį

2007 ◽  
Vol 5 (4) ◽  
pp. 0-0
Author(s):  
Edita Mišeikytė Kaubrienė ◽  
Albertas Ulys ◽  
Mantas Trakymas ◽  
Jolita Rimienė

Edita Mišeikytė Kaubrienė1,  Albertas Ulys1, Mantas Trakymas1,  Jolita Rimienė21 Vilniaus universiteto Onkologijos institutas, Santariškių g. 1, LT-08660 Vilnius2 Valstybinis patologijos centras, Santariškių g. 1, LT-08660 VilniusEl paštas: [email protected] Plonos adatos aspiracinė biopsija yra patikimiausias skydliaukės mazgų diagnostikos metodas („aukso standartas“). Plonos adatos aspiracinė biopsinė – tai pradinis čiuopiamų ir nečiuopiamų skydliaukės mazgų stebėjimo ir gydymo strategijos žingsnis. Šio diagnostikos metodo patikimumui turi įtakos tyrėjų, atliekančių aspiracines biopsijas ir citologinius tyrimus, įgūdžiai, ypač svarbūs diferencijuojant nepiktybinius ir piktybinius folikulinius pakitimus. Tyrimas leidžia sumažinti dėl mazginės strumos atliekamų tiroidektomijų skaičių. Šios literatūros apžvalgos tikslas – įvertinti plonos adatos aspiracinės biopsijos reikšmę diagnozuojant skydliaukės mazgus. Straipsnyje pateikiamas plonos adatos aspiracinės biopsijos rezultatų įvertinimas. Daroma išvada, kad skydliaukės mazgų plonos adatos aspiracinė biopsija yra saugus, nebrangus, minimaliai invazinis ir informatyvus tyrimo metodas. Pagrindiniai žodžiai: skydliaukės mazgas, skydliaukės vėžys, ultragarsinis tyrimas, plonos adatos aspiracinė biopsijaFine-needle aspiration biopsy in thyroid cancer diagnostics Edita Mišeikytė Kaubrienė1,  Albertas Ulys1, Mantas Trakymas1,  Jolita Rimienė21 Institute of Oncology Vilnius University, Santariškių str. 1, LT-08660 Vilnius, Lithuania2 National Center of Pathology, Santariškių str. 1, LT-08660 Vilnius, LithuaniaE-mail: [email protected] Fine-needle aspiration biopsy is considered the most reliable test, a “gold standard” for the diagnosis of thyroid nodules. Fine-needle aspiration biopsy has made its mark as an initial diagnostic step in the management of palpable and nonpalpable thyroid nodules. Limitations of fine-needle aspiration are related to the skill of the aspirator, the expertise of the cytologist, and the difficulty in distinguishing some benign cellular adenomas from their malignant counterparts. This technique has resulted in an overall decline in the number of thyroidectomies performed for thyroid nodules. The objective of the article is to review the literature on the utility of fine-needle aspiration biopsy in the diagnostic management of nodular thyroid disease. Fine-needle aspiration biopsy of the thyroid gland is a safe, inexpensive, minimally invasive and highly accurate test in the diagnosis of nodular thyroid disease. Keywords: thyroid nodule, thyroid cancer, ultrasound, fine-needle aspiration biopsy

Cancer ◽  
1987 ◽  
Vol 59 (6) ◽  
pp. 1206-1209 ◽  
Author(s):  
Federico Hawkins ◽  
Diego Bellido ◽  
Carmen Bernal ◽  
Demetra Rigopoulou ◽  
Maria Pilar Ruiz Valdepeñas ◽  
...  

PEDIATRICS ◽  
1995 ◽  
Vol 95 (1) ◽  
pp. 46-49
Author(s):  
Stephen S. Raab ◽  
Jan F. Silverman ◽  
Tarik M. Elsheikh ◽  
Patricia A. Thomas ◽  
Paul E. Wakely

Objective. The prevalence of thyroid nodularity in children has been estimated to be 1.8%. The reported prevalence of specific diseases which comprise these nodules is conflicting as evidenced by a reported range of malignancy of 2 to 50% in solitary nodules. In order to better classify pediatric (<18 years old) thyroid disease and evaluate the utility of fine needle aspiration biopsy (FNAB) in this patient population, we retrospectively reviewed 66 FNABs from 64 thyroid nodules and 2 perithyroid lymph nodes from 57 patients. Methodology. Patients: The study was composed of 8 males and 49 females who ranged in age from 1 to 18 years old (mean = 13.1). Design: Surgical and/or clinical follow-up was obtained in all patients. The 66 FNAB diagnoses were initially classified into specific diseases. However, for the purpose of this review, the cases were classified as: 3 insufficient, 51 benign, 8 suspicious, and 4 malignant. Results. There were no "false positives" and one "false negative" (a papillary carcinoma was misdiagnosed as a benign nodule). Overall, 10 patients (18%) had malignant thyroid lesions, including 8 papillary carcinomas and 2 follicular carcinomas. Benign diagnoses included benign nodule, cyst, lymphocytic thyroiditis, granulomatous thyroiditis, hyperplasia, and abscess. Conclusions. The prevalence of malignancy in pediatric patients with thyroid nodules was 18%. We conclude that, because of its high diagnostic accuracy and minimal invasiveness, FNAB is useful in the management of pediatric thyroid nodules.


Cancer ◽  
1988 ◽  
Vol 62 (7) ◽  
pp. 1337-1342 ◽  
Author(s):  
Annette R. Nathan ◽  
Kristen B. Raines ◽  
Yeu-Tsu Margaret Lee ◽  
E. Lawrence Sakas ◽  
Judy M. Ribbing

2017 ◽  
Vol 9 (3) ◽  
pp. 100-103
Author(s):  
Saad Alqahtani ◽  
Saif Alsobhi ◽  
Riyadh I Alsalloum ◽  
Saleh N Najjar ◽  
Hindi N Al-Hindi

ABSTRACT Aim To correlate selected clinical and ultrasonographic (US) characteristics with the final histopathological diagnosis in patients with atypia of undetermined significance (AUS) and follicular lesion of undetermined significance (FLUS), and whether this information can be used in planning the surgical approach. Materials and methods It is a retrospective study including the operated cases of AUS/FLUS from 2011 to 2014 treated at one center. Results This cohort included 87 women and 28 men. To test for independence between categorical variables, the chi-square test was used. There was no significant correlation between age or US variables and final pathological diagnosis. However, final diagnosis of malignancy was higher in men compared with women (64.3 and 41.4% respectively; p = 0.035). Furthermore, a significant association between the diagnosis of repeated fine needle aspiration biopsy (FNAB) and the final pathological diagnosis was noted (benign vs malignant, p = 0.005). Conclusion The FNAB has a significant role in the assessment of thyroid nodules. Our results showed no correlation between age, US variables, and the risk of malignancy. Male gender is associated with higher risk of malignancy. Clinical significance Determining the risk of malignancy and prediction of surgical outcome may help triaging cases for repeat FNA or proceeding to surgery. How to cite this article Alqahtani S, Alsobhi S, Alsalloum RI, Najjar SN, Al-Hindi HN. Surgical Outcome of Thyroid Nodules with Atypia of Undetermined Significance and Follicular Lesion of Undetermined Significance in Fine Needle Aspiration Biopsy. World J Endoc Surg 2017;9(3):100-103.


1993 ◽  
Vol 166 (4) ◽  
pp. 346-349 ◽  
Author(s):  
Irving B. Rosen ◽  
Abbas Azadian ◽  
Paul G. Walfish ◽  
Shia Salem ◽  
Edward Lansdown ◽  
...  

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