The Etiology of Bullous Myringitis and the Role of Mycoplasmas in Ear Disease: A Review

PEDIATRICS ◽  
1980 ◽  
Vol 65 (4) ◽  
pp. 761-766 ◽  
Author(s):  
Donald B. Roberts

A critical review of the literature concerning bullous myringitis has found one case of possible mycoplasmal, one of possible viral, and 43 of bactenal, etiology. The bacteria were Streptococcus pneumoniae, Haemophilus influenzae, and β-hemolytic Streptococcus, in the same percentages as found in (nonbullous) otitis media. One of 858 attempts to isolate Mycoplasma from cases of (nonbullous) otitis media was successful. The evidence that Mycoplasma are a cause of otitis media with or without bullae is weak. Bullous myringitis probably is not a separate clinical entity, but merely acute otitis media with blisters on the eardrum.

1985 ◽  
Vol 7 (2) ◽  
pp. 51-52

A literature review regarding bullous myringitis revealed ony one case due to culturally proven Mycoplasma pneumoniae among 16 cultured cases. In addition, there was only one case of viral (adenovirus) bullous myringitis in 13 appropriately cultured patients. Forty-three of 66 patients for whom bacterial cultures were performed revealed bullous myringitis due to pneumococcus (21 cases), due to Haemophilus influenzae (14 cases), and due to β-hemolytic Streptococcus (ten cases). Thus, bullous myringitis is "... merely acute otitis media with blisers within the substance of the eardrum ... bullous myringitis should be treated the same as other types of acute otitis media." Comment: There are few or no data to support the role of any specific agent as the cause of bullous myringitis, nor is there reason to believe that bullous myringitis is a specific entity.


Medicine ◽  
2017 ◽  
Vol 96 (6) ◽  
pp. e5974 ◽  
Author(s):  
Andres Rosenblut ◽  
Carla Napolitano ◽  
Angelica Pereira ◽  
Camilo Moreno ◽  
Devayani Kolhe ◽  
...  

2003 ◽  
Vol 22 (6) ◽  
pp. 509-514 ◽  
Author(s):  
EUGENE LEIBOVITZ ◽  
ROBERT SATRAN ◽  
LOLITA PIGLANSKY ◽  
SIMON RAIZ ◽  
JOSEPH PRESS ◽  
...  

1988 ◽  
Vol 7 (7) ◽  
pp. 476-479 ◽  
Author(s):  
B. ANDERSSON ◽  
B. M. GRAY ◽  
H. C. DILLON ◽  
A. BAHRMAND ◽  
C. SVANBORG EDÉN

2000 ◽  
Vol 44 (1) ◽  
pp. 43-50 ◽  
Author(s):  
Ron Dagan ◽  
Eugene Leibovitz ◽  
Dan M. Fliss ◽  
Alberto Leiberman ◽  
Michael R. Jacobs ◽  
...  

ABSTRACT A prospective, open-label, randomized study was conducted in order to determine the bacteriologic efficacies of cefaclor and azithromycin in acute otitis media (AOM). Tympanocentesis was performed on entry into the study and 3 to 4 days after initiation of treatment. Bacteriologic failure after 3 to 4 days of treatment with both drugs occurred in a high proportion of culture-positive patients, especially in those in whom AOM was caused by Haemophilus influenzae(16 of 33 [53%] of those treated with azithromycin and 13 of 34 [52%] of those treated with cefaclor). Although a clear correlation of the persistence of the pathogen with increased MICs of the respective drugs could be demonstrated for Streptococcus pneumoniae, no such correlation was found for H. influenzae. It is proposed that susceptibility breakpoints forH. influenzae should be considerably lower than the current ones for both cefaclor and azithromycin for AOM caused by H. influenzae.


2007 ◽  
Vol 51 (6) ◽  
pp. 2230-2235 ◽  
Author(s):  
Kimberley Clawson Stone ◽  
Ron Dagan ◽  
Adriano Arguedas ◽  
Eugene Leibovitz ◽  
Elaine Wang ◽  
...  

ABSTRACT Faropenem was tested against 1,188 middle ear fluid pathogens from children in Israel and Costa Rica. Against Streptococcus pneumoniae and Haemophilus influenzae, faropenem was the most active β-lactam, with activity that was similar to or greater than of the other oral antimicrobial classes studied. Faropenem was also active against Moraxella catarrhalis and Streptococcus pyogenes.


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