Notes from the Field: Injection Safety and Vaccine Administration Errors at an Employee Influenza Vaccination Clinic — New Jersey, 2015

Egg allergy is not necessarily a contraindication to influenza vaccination. For patients with suspected egg allergy, if the clinician determines benefits to outweigh risks, cautionary measures are available that can enhance safe vaccine administration. Batch to batch variability of egg content in extant influenza vaccines necessitates an informed and cautious approach to vaccination of an egg allergic individual. Although patients with egg allergy are likely to develop egg tolerance by late childhood, tolerance to ingestion of “baked egg” products may not predict tolerance to “native egg” proteins present in the influenza vaccine. Even in cases where the skin test to the vaccine is positive, vaccination may still be cautiously administered, if necessary, in a graded dose protocol.

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Prevalence and Trend in the Use of Hospital-Based Standing Orders Programs for Influenza and Pneumococcal Vaccination

Infection Control and Hospital Epidemiology ◽

10.1086/519208 ◽

2007 ◽

Vol 28 (8) ◽

pp. 899-904 ◽

Cited By ~ 1

Author(s):

Sri Ram Pentakota ◽

William Halperin

Keyword(s):

New Jersey ◽

Influenza Vaccination ◽

Acute Care ◽

State Government ◽

Pneumococcal Vaccination ◽

Acute Care Hospitals ◽

Health Department ◽

The State ◽

Healthcare Facilities ◽

Hospital Characteristics

Background.In 2002, federal regulations authorized the use of standing orders programs (SOPs) for promoting influenza and pneumococcal vaccination. In 2003, the New Jersey Hospital Association conducted a demonstration project illustrating the efficacy of SOPs, and the state health department informed healthcare facilities of their benefits. We describe the prevalence of reported use of SOPs in New Jersey hospitals in 2003 and 2005 and identify hospital characteristics associated with the use of SOPs.Methods.A survey was mailed to the directors of infection control at 117 New Jersey hospitals during the period from January to May 2005 (response rate, 90.6%). Data on hospital characteristics were obtained from hospital directories and online resources.Results.The prevalence of use of SOPs for influenza vaccination was 50% (95% confidence interval [CI], 40.1%-59.9%) in 2003, and it increased to 78.3% (95% CI, 69.2%-85.7%) in 2005. The prevalence of SOP use for pneumococcal vaccination was similar. In 2005, the reported rate of use of SOPs for inpatients (influenza vaccination, 76.4%; pneumococcal vaccination, 75.5%) was significantly higher than that for outpatients (influenza vaccination, 9.4%; pneumococcal vaccination, 8.5%). Prevalence ratios for SOP use comparing acute care and non-acute care hospitals were 1.71 (95% CI, 1.2-2.5) for influenza vaccination SOPs and 1.8 for (95% CI, 1.2-2.7) pneumococcal vaccination SOPs. Acute care hospitals with a ratio of admissions to total beds greater than 36.7 reported greater use of SOPs for pneumococcal vaccination, compared with those that had a ratio of less than 36.7.Conclusion.The increase in the prevalence of reported use of SOPs among New Jersey hospitals in 2005, compared with 2003, was contemporaneous with SOP-related actions taken by the federal government, the state government, and the New Jersey Hospital Association. Opportunities persist for increased use of SOPs among non-acute care hospitals and for outpatients.

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Cutaneous Leukocytoclastic Vasculitis Following Influenza Vaccination in Older Adults: Report of Bullous Purpura in an Octogenarian after Influenza Vaccine Administration

Cureus ◽

10.7759/cureus.2323 ◽

2018 ◽

Author(s):

Stella X Chen ◽

Philip R Cohen

Keyword(s):

Older Adults ◽

Influenza Vaccine ◽

Influenza Vaccination ◽

Leukocytoclastic Vasculitis ◽

Vaccine Administration

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Acute Exercise as an Adjuvant to Influenza Vaccination

American Journal of Lifestyle Medicine ◽

10.1177/1559827610395486 ◽

2011 ◽

Vol 5 (6) ◽

pp. 512-517 ◽

Cited By ~ 7

Author(s):

Kate M. Edwards ◽

John P. Campbell

Keyword(s):

Immune Response ◽

Immune Responses ◽

Antibody Response ◽

Influenza Vaccination ◽

Acute Exercise ◽

Task Characteristics ◽

Vaccine Administration ◽

Human Trials ◽

Animal Data ◽

Exercise Induced

Acute exercise prior to vaccine administration can improve the immune response. Animal data are now supported by human trials, which have shown that immune responses are enhanced by a bout of acute exercise before innoculation; this effect is particularly prominent in vaccines that normally produce weak immune responses. Although there remain many aspects of this phenomenon to be investigated, including task characteristics such as duration and form of exercise, it appears that even a moderate bout of exercise of the muscles into which vaccine will be administered can enhance the antibody response. In this review, the authors will summarize the animal and human literature and discuss the investigation of potential mechanisms of acute exercise–induced immunoenhancement.

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Measured Performance and Vaccine Administration After Decision Support and Office Workflow Changes for Influenza Vaccination

Journal for Healthcare Quality ◽

10.1097/jhq.0000000000000243 ◽

2020 ◽

Vol 42 (6) ◽

pp. 333-340

Author(s):

Stephen D. Persell ◽

Nora Lewin ◽

Banu Yagci ◽

Ji Young Lee ◽

Sonali K. Oberoi ◽

...

Keyword(s):

Decision Support ◽

Influenza Vaccination ◽

Vaccine Administration

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Vaccinating High-Risk Pediatric Patients and Their Families in the Hospital Setting: Give It a Shot!

Open Forum Infectious Diseases ◽

10.1093/ofid/ofx163.758 ◽

2017 ◽

Vol 4 (suppl_1) ◽

pp. S322-S323

Author(s):

Rebecca Barros ◽

Wendi Gornick ◽

M Tuan Tran ◽

Beth Huff ◽

Jasjit Singh

Keyword(s):

High Risk ◽

Influenza Vaccine ◽

Influenza Vaccination ◽

Vaccination Rate ◽

Influenza Vaccines ◽

Hospitalized Children ◽

Care Hospital ◽

Vaccine Administration ◽

High Risk Patients ◽

Risk Patients

Abstract Background Hospitalization and hospital-based clinics confer an opportunity to target high-risk patients and their families who would benefit from vaccination. Methods CHOC Children’s Hospital is a tertiary-care hospital in Southern California with 11,995 admissions in 2016, including 1,580 hematology/oncology (HO) admissions. We examined the trend in influenza vaccine administration in hospitalized and HO patients over the last decade. We assessed the trend in Tdap and influenza vaccine administration among parents of hospitalized children. We correlated those trends with disease outbreaks in the community and educational and programmatic efforts at our institution. Results After educational efforts, the influenza vaccination rate in 2017 compared with 2006 increased 13-fold in hospitalized patients and increased 9-fold among hospitalized HO patients. During the H1N1 pandemic in 2009, influenza vaccination rates increased 470% from the year prior (Figure 1). The number of influenza vaccines administered in the clinic to HO patients was 494 and 408 in 2015–2016 and 2016–2017, respectively. Following program initiation, the number of Tdap vaccines administered to parents during their child’s hospitalization increased from 57 doses in 2013 to 118 doses in 2016. The trend in vaccination roughly followed pertussis outbreak cases (Figure 2). The number of influenza vaccines administered to parents of HO patients during their child’s clinic visit increased from 44 doses given in 2015–2016 to 306 doses given in 2016–2017 (Figure 3). At our institution, among staff we achieved a 98% vaccination rate for Tdap and influenza in 2017. There were no serious adverse events reported after patient, parent or staff vaccination during this time period. Conclusion Missed opportunities for vaccination of high-risk children include hospitalization and specialty clinic visits. Creating a culture of vaccination and public perception of vaccine importance during outbreaks can increase the influenza vaccination rate among high-risk, hospitalized and HO patients. Programs targeting families of high-risk patients are an opportunity to cocoon a vulnerable population. Vaccination of hospitalized children, their parents and staff is safe in these settings. Disclosures All authors: No reported disclosures.

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