scholarly journals Energy of blood circulation in primary reduction of myocardial contractility

2020 ◽  
Vol 0 (5 (38)) ◽  
pp. 10-14
Author(s):  
Kostiantyn Mykhnevych
2009 ◽  
Vol 40 (2) ◽  
pp. 55-65 ◽  
Author(s):  
Thomas F. Pettigrew

This paper reviews the evidence for a secondary transfer effect of intergroup contact. Following a contact’s typical primary reduction in prejudice toward the outgroup involved in the contact, this effect involves a further, secondary reduction in prejudice toward noninvolved outgroups. Employing longitudinal German probability samples, we found that significant secondary transfer effects of intergroup contact exist, but they were limited to specific outgroups that are similar to the contacted outgroup in perceived stereotypes, status or stigma. Since the contact-prejudice link is bidirectional, the effect is inflated when prior prejudice reducing contact is not controlled. The strongest evidence derives from experimental research. Both cognitive (dissonance) and affective (evaluative conditioning) explanations for the effect are offered.


2012 ◽  
Vol 60 (S 01) ◽  
Author(s):  
H Weiler ◽  
O Moeller ◽  
M Wohlhoefer ◽  
LO Conzelmann ◽  
J Albers ◽  
...  

2015 ◽  
Vol 46 (S 01) ◽  
Author(s):  
R. Lampe ◽  
N. Botkin ◽  
V. Turova ◽  
T. Blumenstein ◽  
A. Alves-Pinto

2005 ◽  
Vol 44 (03) ◽  
pp. 107-117
Author(s):  
R. G. Meyer ◽  
W. Herr ◽  
A. Helisch ◽  
P. Bartenstein ◽  
I. Buchmann

SummaryThe prognosis of patients with acute myeloid leukaemia (AML) has improved considerably by introduction of aggressive consolidation chemotherapy and haematopoietic stem cell transplantation (SCT). Nevertheless, only 20-30% of patients with AML achieve long-term diseasefree survival after SCT. The most common cause of treatment failure is relapse. Additionally, mortality rates are significantly increased by therapy-related causes such as toxicity of chemotherapy and complications of SCT. Including radioimmunotherapies in the treatment of AML and myelodyplastic syndrome (MDS) allows for the achievement of a pronounced antileukaemic effect for the reduction of relapse rates on the one hand. On the other hand, no increase of acute toxicity and later complications should be induced. These effects are important for the primary reduction of tumour cells as well as for the myeloablative conditioning before SCT.This paper provides a systematic and critical review of the currently used radionuclides and immunoconjugates for the treatment of AML and MDS and summarizes the literature on primary tumour cell reductive radioimmunotherapies on the one hand and conditioning radioimmunotherapies before SCT on the other hand.


1990 ◽  
Vol 29 (01) ◽  
pp. 7-12 ◽  
Author(s):  
J. Bialy ◽  
F.-J. Hans ◽  
E. Oberhausen ◽  
W.J. Peters ◽  
M. Schmitt ◽  
...  

A method is being developed which not only measures cerebral blood flow as a static quantity but also its changes with time. For that purpose a semiconductor device ascertains the proportion of intracerebral81 Rb and 81mKr activities. By opening the haemato-encephalic barrier in animal experiments a sufficient concentration of intracerebral81 Rb could be attained and the modified blood circulation after step-wise ligature of all brain arteries brought into relation to the corresponding Rb/Kr quotient. Over the range from undisturbed to completely interrupted cerebral blood flow this quotient varied up to 25% of its initial value.


1976 ◽  
Vol 36 (03) ◽  
pp. 503-508 ◽  
Author(s):  
Raymund Machovich ◽  
György Blaskó ◽  
Anna Borsodi

SummaryInactivation of α- and β-thrombin by antithrombin-III and heparin was studied, since it had been suggested that two forms of thrombin exist with respect to heparin sensitivity (Machovich 1975b).It was found that the inactivation rates of α- and β-thrombin by antithrombin were different, namely α-thrombin was more sensitive to antithrombin than β-thrombin. Heparin facilitated the complex formation between α-thrombin and antithrombin-III, whereas β-thrombin inactivation was only slightly affected.Furthermore, heparin protected α-thrombin against the inactivating effect of heat, while β-thrombin lost its activity during the heat treatment.These findings suggest that the formation of β-thrombin in blood circulation may have an important role in thrombosis predisposition.


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