This book examines the meanings of purification practices and purity concepts in early Christian culture, as articulated and formed by Greek Christian authors of the first three centuries, from Paul to Origen. Concepts of purity and defilement were pivotal for understanding human nature, sin, history, and ritual in early Christianity. In parallel, major Christian practices, such as baptism, abstinence from food or sexual activity, were all understood, felt, and shaped as instances of purification. Two broad motivations, at some tension with each other, formed the basis of Christian purity discourse. The first was substantive: the creation and maintenance of anthropologies and ritual theories coherent with the theological principles of the new religion. The second was polemic: construction of Christian identity by laying claim to true purity while marking purity practices and beliefs of others (Jews, pagans, or “heretics”) as false. The book traces the interplay of these factors through a close reading of second- and third-century Christian Greek authors discussing dietary laws, death defilement, sexuality, and baptism, on the background of Greco-Roman and Jewish purity discourses. There are three central arguments. First, purity and defilement were central concepts for understanding Christian cultures of the second and third centuries. Second, Christianities developed their own conceptions and practices of purity and purification, distinct from those of contemporary and earlier Jewish and pagan cultures, though decisively influenced by them. Third, concepts and practices of purity and defilement were shifting and contentious, an arena for boundary-marking between Christians and others and between different Christian groups.