scholarly journals Constipation in patients with myofascial pain syndrome as important aspect for clinical and nutritional treatment: A case-control study

2017 ◽  
Vol 30 (5) ◽  
pp. 567-581
Author(s):  
João Araújo BARROS-NETO ◽  
Tascya Morganna de Morais SANTOS ◽  
Matheus Lopes CORTES ◽  
Rosangela Passos de JESUS ◽  
Mariana Carvalho FREITAS ◽  
...  
Keyword(s):  
Pain Intensity ◽  
Case Control Study ◽  
Myofascial Pain ◽  
Pain Syndrome ◽  
Myofascial Pain Syndrome ◽  
Case Control ◽  
Horizontal Line ◽  
Study Results ◽  
Bowel Movements ◽  
Control Study

ABSTRACT Objective To identify the occurrence of constipation in patients with myofascial pain syndrome and to correlate these disorders with the clinical and nutritional variables. Methods This report describes a case-control study performed with 98 adults of both sexs, including 49 patients and 49 individuals without pain. The intensity of the reported pain was evaluated using the Pain Visual Analog Scale, which provided a simple and efficient measurement of pain intensity consisting of a 10cm horizontal line with the ends marked “absence of pain” and “worst possible pain”. The occurrence of constipation was evaluated using the Rome III criteria. A multivariate linear regression was proposed to investigate risk factors between the frequency of bowel movements per week and independent variables this study. Results The mean ages of the patients and controls were 45.9 (7.6) years and 41.2 (12.2) years, respectively. The intensity of the reported pain showed a mean of 7.3 (1.6) points. The likelihood of exhibiting constipation was 4.5 times higher in the patients than in the controls (p=0.001). The number of stools per week was negatively correlated with the intensity of the reported pain (r=-0.613, p<0.001). The use of benzodiazepines was negatively correlated with the frequency of bowel movements per week, while the use of muscle relaxants appeared to increase the frequency of defecation when combined with the use of benzodiazepines and adjusted for the intake of fiber, water and sexs (p=0.037). Conclusion Constipation was a frequent nosological entity in this patient population and the persistence of a change in intestinal motility showed a significant correlation with the pain intensity and low water intake. The reduction of the number of stools per week seems to be associated with the use of benzodiazepines.

Lymphocyte-to-monocyte ratio in predicting the calcific aortic valve stenosis in a Chinese case–control study

2020 ◽  
Vol 14 (14) ◽  
pp. 1329-1339
Author(s):  
Xiaochun Ma ◽  
Huibo Ma ◽  
Yan Yun ◽  
Shanghao Chen ◽  
Xiaofeng Zhang ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Stenosis ◽  
Case Control Study ◽  
Independent Predictor ◽  
Inverse Correlation ◽  
Case Control ◽  
Lymphocyte To Monocyte Ratio ◽  
Study Results ◽  
Chinese Case ◽  
Control Study

Aim: This study examined the role of lymphocyte-to-monocyte ratio (LMR), an inflammatory biomarker, in predicting the severity of calcific aortic valve stenosis (CAVS) in a Chinese case–control study. Results: The LMR significantly decreased in the patients with CAVS compared with healthy controls. An inverse correlation was observed between the severity of stenosis and LMR in the patients. Additionally, the LMR was identified in the multivariate analysis as an independent predictor of severe CAVS. Conclusion: This study provides evidence of an inverse correlation between the severity of CAVS and LMR. LMR could potentially be applied as an independent predictor of severe CAVS and could be incorporated into a novel predictive model.

scholarly journals Vaginal Microbiome Is Associated With Vulvodynia, Vulvar Pain Syndrome: A Case-Control Study

2021 ◽  
Vol 9 (2) ◽  
pp. 100314
Author(s):  
So Yun Park ◽  
Eun Sil Lee ◽  
Sa Ra Lee ◽  
Sung Hoon Kim ◽  
Hee Dong Chae
Keyword(s):  
Case Control Study ◽  
Pain Syndrome ◽  
Case Control ◽  
Vaginal Microbiome ◽  
Vulvar Pain ◽  
Control Study

scholarly journals Influenza A (H1N1) virus infection and TNF-308, IL6, and IL8 polymorphisms in Egyptian population: a case–control study

2019 ◽  
Vol 80 (1) ◽  
Author(s):  
Shaimaa Moustafa Elsayed ◽  
Omayma Mohamed Hassanein ◽  
Nagwa Hassan Ali Hassan
Keyword(s):  
Influenza A ◽  
Case Control Study ◽  
H1n1 Virus ◽  
Case Control ◽  
Severe Illness ◽  
Study Results ◽  
Influenza A H1n1 ◽  
Pandemic Strains ◽  
Study Participants ◽  
Control Study

Abstract Background The importance of influenza is increasing mainly because of the appearance of novel pandemic strains such as swine and avian. Each year, influenza has spread around the world causing about 250,000–500,000 deaths and more than 5 million cases of severe illness. The objective is as follows: evaluating the outcomes of patients with influenza A (H1N1) virus in relation to certain TNF-308, IL6, and IL8 polymorphisms and identifying the associated factors with the severe outcome. Subject and methods This is a case–control study. The cases were patients confirmed by real-time polymerase chain reaction (RT-PCR) to be influenza A (H1N1) virus infected. The controls were healthy individuals. Medical history and outcome of the disease was registered. In all study participants, polymorphisms of TNF rs1800629, IL6 rs18138879, and IL8 rs4073; odds ratio (OR); and the 95% confidence interval (95% CI) were calculated. Results Infection with influenza A (H1N1) virus was associated more with the following genotypes: TNF-308 AA (OR = 4.041; 95% CI = 1.215–13.4) and IL8 AA (OR = 3.273; 95% CI = 1.372–7.805). According to our study results, HCV (OR = 3.2, 95% CI 1.2–8.5), renal disease (OR = 3.4, 95% CI 0.9–13.6), cancer (OR = 3.1, 95% CI 0.3–31.1), TB (OR = 8.4, 95% CI 1.8–39.7), ICU (OR = 2.9, 95%1.2–7.1), and mortality (OR = 7.9, 95% CI 0.9–67.4) are considered as risk factors for influenza A (H1N1)-infected patients. Conclusions Our findings concluded that TNF-308 (AA) and IL8 (AA) polymorphisms may increase the susceptibility to be infected with H1N1influenza virus.

Statin Use Is Associated with Bladder Pain Syndrome/Interstitial Cystitis: A Population-Based Case-Control Study

2015 ◽  
Vol 95 (2) ◽  
pp. 227-232 ◽  
Author(s):  
C.Y. Huang ◽  
S.D. Chung ◽  
L.T. Kao ◽  
H.C. Lin ◽  
L.H. Wang
Keyword(s):  
Case Control Study ◽  
Conditional Logistic Regression ◽  
Pain Syndrome ◽  
Population Based ◽  
Case Control ◽  
Bladder Pain Syndrome ◽  
Bladder Pain ◽  
Epithelial Dysfunction ◽  
Control Study ◽  
Statin Use

Introduction: Statin may induce epithelial dysfunction of the bladder urothelium. Epithelial dysfunction was proposed as one of the major potential etiologies for bladder pain syndrome/interstitial cystitis (BPS/IC). In this study, we examined the association between statin use and BPS/IC using a population-based study. Subjects and Methods: This case-control study used the Taiwan Longitudinal Health Insurance Database. In total, 815 female subjects with BPS/IC and 4075 randomly selected female controls were included. We used a conditional logistic regression to compute the odds ratio (OR) for having previously used statins between cases and controls. Results: A conditional logistic regression analysis showed that the OR of prior statin users for cases was 1.52 (95% confidence interval (CI): 1.19-1.94) compared to controls after adjusting for diabetes, hypertension, coronary heart disease, obesity, chronic pelvic pain, irritable bowel syndrome, fibromyalgia, chronic fatigue syndrome, depression, panic disorder, migraines, sicca syndrome, allergies, endometriosis, and asthma. Furthermore, adjusted ORs of regular and irregular statin use for cases were 1.58 (95% CI: 1.20-2.08) and 1.53 (95% CI: 1.02-2.31), respectively, compared to controls. Conclusion: We concluded that there was an association between statin use and BPS/IC.

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