scholarly journals Influence of body composition on the bone mass of postmenopausal women

1997 ◽  
Vol 115 (6) ◽  
pp. 1580-1588 ◽  
Author(s):  
Marília Martins Silveira Marone ◽  
Cecília Helena de Azevedo Gouveia ◽  
Shlomo Lewin ◽  
Salim Wehba ◽  
Luiz Fernando Malvestiti ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mass ◽  
Postmenopausal Women ◽  
Dual Energy ◽  
Mineral Density ◽  
Main Determinant ◽  
X Ray ◽  
Almost All ◽  
Positive Effect ◽  
Main Factor

AIMS:To investigate the influence of body weight (BW), fat mass (FM) and lean mass (LM) on the bone mineral density (BMD) of several areas of the skeleton. PARTICIPANTS: Sixty one white postmenopausal women (50.1±4.8 years). MEASUREMENTS: Measurement of BMD by dual energy x-ray absorptiometry. The results were analyzed by linear regression and the slopes of each curve were compared. RESULTS: The results showed that the correlations between BW, FM and LM to BMD were positive, whilst the correlations between age and years since menopause to BMD were negative. LM was the main factor that influenced BMD in almost all areas. CONCLUSIONS: FM and LM present a positive effect on BMD, although LM is the main determinant of bone mass. Moreover, higher values of LM and FM present a protective effect against the reduction of BMD combined with menopause. Therefore postmenopausal women with low BW, especially low LM, present serious risk for developing osteoporosis.

Increased Bone Accrual in Premenarcheal Gymnasts: A Longitudinal Study

2005 ◽  
Vol 17 (2) ◽  
pp. 149-160 ◽  
Author(s):  
Nicole Gero ◽  
Jacque Cole ◽  
Jill Kanaley ◽  
Marjolein van der Meulen ◽  
Tamara Scerpella
Keyword(s):  
Bone Mineral Density ◽  
Longitudinal Study ◽  
Femoral Neck ◽  
Bone Mineral ◽  
Dual Energy ◽  
Mineral Density ◽  
X Ray ◽  
Total Hip ◽  
Positive Effect

This longitudinal study evaluates the role of impact activity in bone accrual in premenarcheal girls. Twenty-eight gymnasts and 20 controls underwent 1-year analysis; fifteen gymnasts and 8 controls underwent 2-year analysis. Bone mineral density (BMD) was measured yearly by dual energy X-ray absorptiometry. For the 1-year analysis, BMD accrual rates were greater in gymnasts than controls at the forearm only (p < .05). For the 2-year analysis, gains in BMD were 1.5 to 1.9 times greater at the forearm, total hip, and femoral neck for gymnasts (p < .05). These findings confirm the positive effect of impact activity on bone accrual in premenarcheal girls.

Correlation of Quantitative Heel Ultrasonography With Central Dual-Energy X-ray Absorptiometric Bone Mineral Density in Postmenopausal Women

2005 ◽  
Vol 24 (7) ◽  
pp. 941-946 ◽  
Author(s):  
Bagher Larijani ◽  
Mohammad Hossein Dabbaghmanesh ◽  
Shahriar Aghakhani ◽  
Mojtaba Sedaghat ◽  
Zohreh Hamidi ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Dual Energy ◽  
Mineral Density ◽  
X Ray

scholarly journals Pre and Postmenopausal Changes of Bone Mineral Density: A Comparative Study done by Dual Energy X-Ray Absorptiometry

2013 ◽  
Vol 22 (1) ◽  
pp. 1-7
Author(s):  
M Begum ◽  
MI Patwary ◽  
MA Ahbab ◽  
MH Khan ◽  
AI Chowdhury ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Femoral Neck ◽  
Comparative Study ◽  
Postmenopausal Women ◽  
Negative Correlation ◽  
Premenopausal Women ◽  
Dual Energy ◽  
Mineral Density ◽  
X Ray ◽  
Lumber Vertebrae

Background: Accelerated decline of bone mass occurs in women after the menopause, and might lead to excessive bone resorption and eventually to osteoporosis. To find out the changes of bone mineral density (BMD) before and after menopause, the shown was undertaken. Materials and Methods: This comparative study was conducted in the Department of Medicine, Sylhet M A G Osmani Medical College Hospital, Sylhet during July 2008 to June 2009. Forty postmenopausal women; monthly income and BMI matched 40 premenopausal women were selected according to inclusion and exclusion criteria. BMD of lumber vertebrae and femoral neck was determined using Dual energy x-ray absorptiometry (DXA) method (Norland XR 46, Pencil beam). Results: The parity of the postmenopausal women was significantly higher than that of premenopausal women (6.9 ± 2.6 vs 3.1± 1.5; p<0.01). The body weight was significantly lower in postmenopausal women than that of premenopausal women (54.1 ± 8.3 kg vs 61.0 ± 9.7 Kg; p<0.01). The height was significantly lower in postmenopausal women than premenopausal women (148.2 ± 5.7cm vs 153.4 ± 6.4cm; p<0.01). The BMD was lower in postmenopausal women than premenopausal women in lumber vertebrae (0.68 ± 0.13 gm/cm2 vs 0.94 ± 0.03 gm/cm2; p <0.01) and also in femoral neck (0.63 ± 0.12 gm/cm2 vs 0.84 ± 0.14 gm/cm2; p < 0.01). A significant positive correlation was present between BMD and height (r=0.512; p<0.05); and weight (r=0.489; p<0.05); and a negative correlation between BMD and age (r=-0.408; p<0.05); parity (r=-0.456; p<0.05) and years since menopause (r=-0.350; p<0.05). Conclusion: The BMD was significantly lower in postmenopausal women than that of premenopausal women and negative correlation was present between BMD and age, parity and years since menopause.   DOI: http://dx.doi.org/10.3329/bjmed.v22i1.13592 Bangladesh J Medicine 2011; 22: 1-7

ESTIMATION OF LOW BONE MASS FOR THE ASSESSMENT OF OSTEOPOROSIS FRACTURE RISK IN INDIAN MEN AND WOMEN USING QUANTITATIVE ULTRASOUND AND DUAL ENERGY X-RAY ABSORPTIOMETRY

2004 ◽  
Vol 04 (01) ◽  
pp. 47-59 ◽  
Author(s):  
MALLIKARJUN S. HOLI ◽  
S. RADHAKRISHNAN
Keyword(s):  
Bone Mineral Density ◽  
Bone Mass ◽  
Fracture Risk ◽  
Quantitative Ultrasound ◽  
Dual Energy ◽  
Low Bone Mass ◽  
Mineral Density ◽  
Men And Women ◽  
X Ray ◽  
Indian Men

The objective of the present work is to estimate the prevalence of low bone mass in Indian men and women for the assessment of osteoporosis and fracture risk using quantitative ultrasound and dual energy X-ray absorptiometry (DEXA) and carryout a comparative evaluation for early prediction of osteoporosis. Data collected in this study is analyzed to assess the diagnostic performance of the ultrasound and how its performance compares to DEXA bone mineral density (BMD). Quantitative ultrasound assessment of osteoporosis is carried out by measuring broadband ultrasound attenuation (BUA) and speed of sound (SOS) through calcaneus bone to provide a clinical measure called the stiffness index (SI). The SI is a measure of bone density used to predict the risk of bone fracture due to osteoporosis. Bone mineral density (BMD) measurement is performed in lumbar region (L1–L4) of the spine in anterior-posterior direction using DEXA. In both studies the data is found to be significant in men and women subjects with p<0.0005 and percentage bone loss in men and women are significantly matching in both studies. Ultrasound performance correlates moderately well with DEXA (r=0.60 to 0.68) and provides comparable diagnostic sensitivity to spine BMD in predicting osteoporotic fractures.

scholarly journals Relationship between lifestyle habits of postmenopausal women and altered bone mineral density determined by ultrasound (US) screening and dual energy X-ray absorptiometry (DEXA)

2017 ◽  
Vol 7 (1) ◽  
pp. 59-67
Author(s):  
Amila Jaganjac ◽  
Mirsad Muftić ◽  
Dijana Avdić ◽  
Amra Mačak Hadžiomerović ◽  
Bakir Katana ◽  
...  
Keyword(s):  
Physical Activity ◽  
Bone Mineral Density ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Total Sample ◽  
Dual Energy ◽  
Mineral Density ◽  
Lifestyle Habits ◽  
X Ray ◽  
Heel Bone

Introduction: Osteoporosis is a skeletal system disease characterized by decline of bone mass and deterioration of bone microarchitecture, which leads to increased bone fragility and, consequently, a greater risk of fractures. Postmenopausal osteoporosis generally occurs between 51 and 75 years of age following ovarian failure. Our aim was to investigate if specific lifestyle habits, i.e., smoking cigarettes and physical activity, as well as the intake of dietary supplements, affect bone mineral density (BMD) in postmenopausal women.Methods: Ultrasound (US) and dual energy X-ray absorptiometry (DEXA) data, obtained between 2008 and 2009 year, were retrospectively reviewed for 150 women in postmenopause, 50-65 years old, who live in Sarajevo Canton. The women were classified into two groups: Group A (75 postmenopausal women who underwent US of the left heel bone); control group B (75 postmenopausal women who underwent US of the left heel bone and had a DEXA scan of the lumbar spine and left hip).Results: The study included 150 women with the average age of 55.39 years. In the total sample, 24.7% of women took calcium and vitamin D supplements, and no statistically significant difference was observed between the groups. In the total sample, the prevalence of osteoporosis was significantly different between smokers and nonsmokers; i.e., osteoporosis was more frequent in women who smoked cigarettes. On average, women in both groups reported low physical activity; the difference was not statistically significant.Conclusions: Menopause is a known risk for osteoporosis. Our results showed that the length of menopause is closely associated with osteoporosis occurrence.

Effect of tamoxifen on bone mineral density measured by dual-energy x-ray absorptiometry in healthy premenopausal and postmenopausal women.

1996 ◽  
Vol 14 (1) ◽  
pp. 78-84 ◽  
Author(s):  
T J Powles ◽  
T Hickish ◽  
J A Kanis ◽  
A Tidy ◽  
S Ashley
Keyword(s):  
Breast Cancer ◽  
Bone Mineral Density ◽  
Lumbar Spine ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Premenopausal Women ◽  
Dual Energy ◽  
Mineral Density ◽  
X Ray ◽  
The Mean

PURPOSE Tamoxifen is an effective treatment for metastatic and primary breast cancer and is now being evaluated as a chemoprevention agent in healthy women. Any long-term effects on estrogen-sensitive tissues such as bone may have important therapeutic implications. METHODS We measured bone mineral density (BMD) in the lumbar spine and hip using dual-energy x-ray absorptiometry (DXA) in premenopausal and postmenopausal healthy women who participated in our placebo-controlled tamoxifen chemoprevention of breast cancer trial. RESULTS BMD data are now available from 179 women for this analysis. In premenopausal women, BMD decreased progressively in the lumbar spine (P < .001) and in the hip (P < .05) for women on tamoxifen, but not those on placebo. The mean annual loss in lumbar BMD per year over the 3-year study period in tamoxifen-treated compliant women who remained premenopausal throughout the study period was 1.44% (1.88% calculated on an intent-to-treat basis) compared with a small gain of 0.24% per annum for women on placebo (P < .001). Tamoxifen had the opposite effect in postmenopausal women. The mean annual increase in BMD for women on tamoxifen was 1.17% in the spine (P < .005) and 1.71% in the hip (P < .001) compared with a noninsignificant loss for women on placebo. CONCLUSION These results indicate that tamoxifen treatment is associated with a significant loss of BMD in premenopausal women, whereas it prevents bone loss in postmenopausal women. These adverse and beneficial effects of tamoxifen should be considered in the assessment of the therapeutic benefits for both the adjuvant treatment and the chemoprevention of breast cancer.

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