INTERSTITIAL CELL-STIMULATING HORMONERELEASING ACTIVITY OF HYPOTHALAMIC EXTRACTS IN THE DOG

1966 ◽  
Vol 35 (4) ◽  
pp. 401-408 ◽  
Author(s):  
K. YAMASHITA
Keyword(s):  
Glutamic Acid ◽  
Aspartic Acid ◽  
Butyric Acid ◽  
Median Eminence ◽  
Interstitial Cell ◽  
Brain Regions ◽  
Anterior Hypothalamus ◽  
Catechol Amines ◽  
Intracarotid Administration

SUMMARY The effect of hypothalamic extracts on 17-ketosteroid secretion by the testis of the dog was investigated. Stalk-median eminence extracts produced an increased rate of 17-ketosteroid secretion by the testis but extracts of the anterior hypothalamus caused little or no increase in the testicular output. No effect was obtained after the administration of extracts of the pre-optic, posterior hypothalamic and other brain regions. Stalk-median eminence extracts, after boiling, were still active in stimulating the testis though part of the activity was lost. The extracts failed to increase the testicular output of 17-ketosteroids in the hypophysectomized dog and the response is thus considered to be pituitary-dependent. Furthermore, intracarotid administration of acetylcholine, catechol amines, γ-amino-n-butyric acid (GABA), glutamic acid and aspartic acid did not stimulate testicular 17-ketosteroid secretion.

Free Amino Acids in Human Tonsillar Tissue

1975 ◽  
Vol 21 (3) ◽  
pp. 414-417 ◽  
Author(s):  
Yasuyuki Doi ◽  
Akikatsu Kataura
Keyword(s):  
Amino Acids ◽  
Glutamic Acid ◽  
Aspartic Acid ◽  
Butyric Acid ◽  
Free Amino Acids ◽  
Free Amino ◽  
Age Groups ◽  
Isoleucine Leucine ◽  
Amino Butyric Acid ◽  
Pathological Conditions

Abstract Free amino acids in the tonsils of 20 individuals were measured column chromatographically. Those always found in readily detectable amounts included O-phosphoserine, taurine, O-phosphoethanolamine, aspartic acid, hydroxyproline, threonine, serine, glutamic acid, proline, glycine, alanine, α-amino-n-butyric acid, valine, cystine, methionine, isoleucine, leucine, tyrosine, phenylalanine, ornithine, γ-amino-butyric acid, lysine, histidine, and arginine. Results were compared for three clinical pathological groups and for four age groups. Some abnormal values may result from the pathological conditions.

Nitrogenous compounds in the xylem sap of American elms with Dutch elm disease

1969 ◽  
Vol 47 (7) ◽  
pp. 1061-1065 ◽  
Author(s):  
Dilbagh Singh ◽  
Eugene B. Smalley
Keyword(s):  
Amino Acids ◽  
Glutamic Acid ◽  
Aspartic Acid ◽  
Butyric Acid ◽  
Total Concentration ◽  
Xylem Sap ◽  
Dutch Elm Disease ◽  
Amide Nitrogen ◽  
Nitrogenous Compounds

Thirty-two ninhydrin-positive nitrogenous compounds were present in the xylem sap of 6- to 9-year- old American elms. Twenty-six of these compounds were identified. Total concentration of nitrogenous materials was several times higher in diseased than in healthy sap after inoculation during the susceptible period in the spring, but was lower after inoculations during the late resistant period. Percentage compositions of γ-amino-n-butyric acid, proline, and alanine in diseased sap increased after both spring and mid-summer inoculations. Proline, which was present in trace amounts in healthy sap, constituted 14 to 38% of the total in diseased sap. Percentage concentrations of amide nitrogen in diseased sap were reduced 50% or more in all inoculated trees. Percentages of ammonia, aspartic acid, glutamic acid, and several other amino acids did not change.

Effect of nonessential amino acids on phagostimulation and maintenance of the pea aphid, Acyrthosiphon pisum

1983 ◽  
Vol 61 (10) ◽  
pp. 2224-2229 ◽  
Author(s):  
P. N. Srivastava ◽  
J. L. Auclair ◽  
U. Srivastava
Keyword(s):  
Amino Acids ◽  
Glutamic Acid ◽  
Aspartic Acid ◽  
Butyric Acid ◽  
Acyrthosiphon Pisum ◽  
Prolonged Survival ◽  
Growth And Survival ◽  
Amino Butyric Acid ◽  
Sucrose Solutions ◽  
Nonessential Amino Acids

Eleven nonessential amino acids and amides, at concentrations ranging from 0.001 to 1.0% in 35% sucrose solutions, were individually tested for their role in phagostimulation, growth, and survival in Acyrthosiphon pisum (Harris). Alanine and -γ-amino butyric acid were generally phagostimulatory, whereas asparagine, aspartic acid, cysteine, cystine, glutamic acid, glycine, proline, serine, and tyrosine were generally inhibitory. Asparagine, glutamic acid, glycine, and proline supported growth and prolonged survival; aspartic acid and tyrosine increased weight but did not prolong survival, and alanine, -γ-amino butyric acid, cystine, cysteine, and serine neither promoted growth nor prolonged survival.

IN VITRO UPTAKE OF TRITIATED SEX STEROIDS BY THE HYPOTHALAMUS OF ADULT MALE RATS TREATED NEONATALLY WITH AN ANTIANDROGEN (CYPROTERONE)

1972 ◽  
Vol 71 (1) ◽  
pp. 45-54 ◽  
Author(s):  
Pentti Tuohimaa ◽  
Mikko Niemi
Keyword(s):  
Cerebral Cortex ◽  
Median Eminence ◽  
Sex Steroids ◽  
Leydig Cells ◽  
Interstitial Cell ◽  
Anterior Hypothalamus ◽  
Male Rats ◽  
Corpora Lutea ◽  
In Vitro Uptake

ABSTRACT Male rats were injected subcutaneously with 2 mg of cyproterone daily from birth to the 14th postnatal day. At the age of 40 days the animals were polycystic and corpora lutea were absent. There was an increased 37% of the ovarian implants showed distinct corpora lutea indicating cyclic secretion of gonadotrophins; the implants in the control animals were polycystic and corpora lutea were absent. There was an increased interstitial cell stimulating hormone output from the pituitary gland as indicated by the increased amount of 3β-hydroxysteroid dehydrogenase active Leydig cells in the testes of the feminized animals. The in vitro uptake of tritiated testosterone and oestradiol of various tissues was tested on rats, age 4.5 months. The anterior hypothalamus, the rostral middle hypothalamus, the median eminence and the anterior pituitary of the feminized males retained significantly more oestradiol than the cerebral cortex. The oestradiol uptake in these areas also exceeded that of the control animals. Only the median eminence of the cyproterone treated rats concentrated more testosterone than the cerebral cortex. The anterior hypothalamus and cerebral cortex of the feminized male rats were less able to transform tritiated testosterone to dihydrotestosterone or tritiated oestradiol to oestrone, as compared to adult castrated male or female animals, respectively.

scholarly journals Dietary glutamic acid and aspartic acid as biomarkers for predicting diabetic retinopathy

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
So Young Park ◽  
Jieun Kim ◽  
Jung Il Son ◽  
Sang Youl Rhee ◽  
Do-Yeon Kim ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Glutamic Acid ◽  
Aspartic Acid ◽  
Education Level ◽  
Screening Rate ◽  
Food Records ◽  
Acid Intake ◽  
Lower Education Level ◽  
Lower Education

AbstractThe screening rate of diabetic retinopathy (DR) is low despite the importance of early diagnosis. We investigated the predictive value of dietary glutamic acid and aspartic acid for diagnosis of DR using the Korea National Diabetes Program cohort study. The 2067 patients with type 2 diabetes without DR were included. The baseline intakes of energy, glutamic acid and aspartic acid were assessed using a 3-day food records. The risk of DR incidence based on intake of glutamic acid and aspartic acid was analyzed. The DR group was older, and had higher HbA1c, longer DM duration, lower education level and income than non-DR group (all p < 0.05). The intake of total energy, glutamic acid and aspartic acid were lower in DR group than non-DR group (p = 0.010, p = 0.025 and p = 0.042, respectively). There was no difference in the risk of developing DR according to the intake of glutamic acid and ascorbic acid. But, aspartic acid intake had a negative correlation with PDR. Hence, the intake of glutamic acid and aspartic acid did not affect in DR incidence. However, lower aspartic acid intake affected the PDR incidence.

Biodegradation of copoly(L-aspartic acid/L-glutamic acid) in vitro

Biopolymers ◽  
1990 ◽  
Vol 29 (3) ◽  
pp. 549-557 ◽  
Author(s):  
Toshio Hayashi ◽  
Makoto Iwatsuki
Keyword(s):  
Glutamic Acid ◽  
Aspartic Acid

scholarly journals Utilization in vivo of glucose and volatile fatty acids by sheep brain for the synthesis of acidic amino acids

1966 ◽  
Vol 101 (3) ◽  
pp. 591-597 ◽  
Author(s):  
R M O'Neal ◽  
R E Koeppe ◽  
E I Williams
Keyword(s):  
Amino Acids ◽  
Fatty Acids ◽  
Glutamic Acid ◽  
Aspartic Acid ◽  
Free Amino Acids ◽  
Free Amino ◽  
Specific Activity ◽  
Tricarboxylic Acid Cycle ◽  
Sheep Brain ◽  
The Brain

1. Free glutamic acid, aspartic acid, glutamic acid from glutamine and, in some instances, the glutamic acid from glutathione and the aspartic acid from N-acetyl-aspartic acid were isolated from the brains of sheep and assayed for radioactivity after intravenous injection of [2-(14)C]glucose, [1-(14)C]acetate, [1-(14)C]butyrate or [2-(14)C]propionate. These brain components were also isolated and analysed from rats that had been given [2-(14)C]propionate. The results indicate that, as in rat brain, glucose is by far the best precursor of the free amino acids of sheep brain. 2. Degradation of the glutamate of brain yielded labelling patterns consistent with the proposal that the major route of pyruvate metabolism in brain is via acetyl-CoA, and that the short-chain fatty acids enter the brain without prior metabolism by other tissue and are metabolized in brain via the tricarboxylic acid cycle. 3. When labelled glucose was used as a precursor, glutamate always had a higher specific activity than glutamine; when labelled fatty acids were used, the reverse was true. These findings add support and complexity to the concept of the metabolic; compartmentation' of the free amino acids of brain. 4. The results from experiments with labelled propionate strongly suggest that brain metabolizes propionate via succinate and that this metabolic route may be a limited but important source of dicarboxylic acids in the brain.

Sign in / Sign up

Export Citation Format

Share Document