Diagnostic capabilities of intradermal spectrophotometric analysis in the differential diagnosis of melanocytic skin lesions

2018 ◽  
Vol 17 (3) ◽  
pp. 52
Author(s):  
A. V. Sokolova ◽  
N. P. Malishevskaya
Keyword(s):  
Differential Diagnosis ◽  
Skin Lesions ◽  
Spectrophotometric Analysis ◽  
Diagnostic Capabilities

Assessing the diagnostic capabilities of the app DemDx in an acute care setting (Preprint)

2018 ◽  
Author(s):  
Cian Murphy
Keyword(s):  
Differential Diagnosis ◽  
Care Setting ◽  
Medical Student Education ◽  
Initial Assessment ◽  
Junior Doctors ◽  
Doctor Who ◽  
Clinical Accuracy ◽  
Education Tool ◽  
Clinical Records ◽  
Diagnostic Capabilities

UNSTRUCTURED DemDx is a differential diagnosis app for students and junior doctors. Starting with a patient’s presenting complaint the app goes through a step-by-process through history, examination and investigation findings to an increasingly refined differential diagnosis list until a single most likely diagnosis is reached. The aim of this project was to assess the accuracy of DemDx in an Emergency Department (ED) setting. Anonymised clinical records for 100 patients were retrospectively obtained from the ED in Beth Israel, Boston, USA. This contained the differential diagnoses from the clerking doctor, who performed the initial assessment (D1). The discharge diagnosis was used as the gold standard diagnosis (D2). D1 agreed with D2 in 74.44% of cases while DemDx agreed with D2 in 85.56% of cases (p=0.0003716). When the first, and thus most likely, differential was taken from D1 and DemDx, they agreed with D2 in 20 and 18.8% of cases, respectively (p=0.1428). This demonstration of the clinical accuracy of the app highlights how it can be a useful medical student education tool.

scholarly journals Skin lesions, differential diagnosis and practical approach to potential survivors of torture

2019 ◽  
Vol 33 (7) ◽  
pp. 1232-1240 ◽  
Author(s):  
K. Clarysse ◽  
M. Grosber ◽  
J. Ring ◽  
J. Gutermuth ◽  
C. Kivlahan
Keyword(s):  
Differential Diagnosis ◽  
Skin Lesions ◽  
Practical Approach ◽  
Survivors Of Torture

scholarly journals Aplasia cutis congenita in a newborn

2021 ◽  
Vol 8 (11) ◽  
pp. 1887
Author(s):  
Sheela Madipelli
Keyword(s):  
Differential Diagnosis ◽  
Newborn Infant ◽  
Skin Lesions ◽  
Congenital Absence ◽  
Aplasia Cutis Congenita ◽  
Surgical Closure ◽  
Live Births ◽  
Common Location ◽  
Scalp Lesion ◽  
Aplasia Cutis

Aplasia cutis congenita (ACC) is a localized congenital absence of skin with a reported incidence of 3 per 10000 live births. Most common location is the scalp. The diagnosis is made clinically. The management of the lesion depends on the size and most of them are managed conservatively but larger lesions need surgical closure. Although aplasia cutis congenita is rare, it is very important for the general pediatrician to recognize this and consider it in the differential diagnosis of skin lesions specially the lesions on the scalp. We present a newborn infant with scalp lesion which was clinically diagnosed as aplasia cutis congenita and was managed conservatively.

Differential Diagnosis of LE-specific Skin Lesions

2006 ◽  
pp. 87-101
Author(s):  
Riccardo Rondinone ◽  
Stefania Bano ◽  
Luca Iaccarino ◽  
Andrea Doria
Keyword(s):  
Differential Diagnosis ◽  
Skin Lesions

scholarly journals P089: Does the use of ultrasound improve diagnosis during simulated trauma scenarios?

CJEM ◽  
2017 ◽  
Vol 19 (S1) ◽  
pp. S108
Author(s):  
D. McLean ◽  
L. Hewitson ◽  
D. Lewis ◽  
J. Fraser ◽  
J. Mekwan ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Diagnostic Performance ◽  
Statistical Tests ◽  
Correct Diagnosis ◽  
Primary Diagnosis ◽  
Point Of Care Ultrasound ◽  
Trauma Patients ◽  
Diagnostic Capabilities ◽  
Attending Physicians ◽  
The Impact

Introduction: Point of care ultrasound (US) is a key adjunct in the management of trauma patients, in the form of the extended focused assessment with sonography in trauma (E-FAST) scan. This study assessed the impact of adding an edus2 ultrasound simulator on the diagnostic capabilities of resident and attending physicians participating in simulated trauma scenarios. Methods: 12 residents and 20 attending physicians participated in 114 trauma simulations utilizing a Laerdal 3G mannequin. Participants generated a ranked differential diagnosis list after a standard assessment, and again after completing a simulated US scan for each scenario. We compared reports to determine if US improved diagnostic performance over a physical exam alone. Standard statistical tests (χ2 and Student t tests) were performed. The research team was independent of the edus2 designers. Results: Primary diagnosis improved significantly from 53 (46%) to 97 (85%) correct diagnoses with the addition of simulated US (χ2=37.7, 1df; p=<0.0001). Of the 61 scenarios where an incorrect top ranked diagnosis was given, 51 (84%) improved following US. Participants were assigned a score from 1 to 5 based on where the correct diagnosis was ranked, with a 5 indicating a correct primary diagnosis. Median scores significantly increased from 3.8 (IQR 3, 4.9) to 5 (IQR 4.7, 5; W=219, p<0.0001).Participants were significantly more confident in their diagnoses after using the US simulator, as shown by the increase in their mean confidence in the correct diagnosis from 53.1% (SD 22.8) to 83.5% (SD 19.1; t=9.0; p<0.0001)Additionally, participants significantly narrowed their differential diagnosis lists from an initial medium count of 3.5 (IQR 2.9, 4.4) possible diagnoses to 2.4 (IQR 1.9, 3; W=-378, p<0.0001) following US. The performance of residents was compared to that of attending physicians for each of the above analyses. No differences in performance were detected. Conclusion: This study showed that the addition of ultrasound to simulated trauma scenarios improved the diagnostic capabilities of resident and attending physicians. Specifically, participants improved in diagnostic accuracy, diagnostic confidence, and diagnostic precision. Additionally, we have shown that the edus2 simulator can be integrated into high fidelity simulation in a way that improves diagnostic performance.

scholarly journals Cutaneous Manifestations of Toxoplasmosis: a Case Report

2014 ◽  
Vol 6 (3) ◽  
pp. 113-119 ◽  
Author(s):  
Sonya Marina ◽  
Valja Broshtilova ◽  
Ivo Botev ◽  
Dimitrina Guleva ◽  
Maria Hadzhiivancheva ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Toxoplasma Gondii ◽  
Complete Resolution ◽  
Skin Lesions ◽  
The Body ◽  
Chemiluminescence Immunoassay ◽  
Cutaneous Manifestations ◽  
Blood Eosinophilia ◽  
The World

Abstract Although toxoplasmosis is one of the most widely spread infections in the world, types that involve the skin are extremely rare. However, skin lesions are not specific; moreover, they are quite diverse, which makes the diagnosis of cutaneous toxoplasmosis rather difficult. Thus, differential diagnosis should include a number of other diseases. We present a case of a 43-year-old immunocompetent man with multiple livid erythematous papules and nodules with yellowish discharge that involved the skin of the body and the extremities. By using electro-chemiluminescence immunoassay, immunoglobulin G antibodies to Toxoplasma gondii were detected in the serum, confirming the diagnosis of toxoplasmosis. The treatment with pyrimethamine and trimethoprim-sulfamethoxazole led to complete resolution of skin lesions. In conclusion, although rare in the dermatological practice, cutaneous toxoplasmosis should be considered in all patients presenting with lymphadenopathy, non-specific skin eruptions, especially nodular and colliquative, blood eosinophilia and histological findigs revealing abundant eosinophilic inflitrations.

scholarly journals Peripheral Ulcerative Keratitis with Pyoderma Gangrenosum

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Adrián Imbernón-Moya ◽  
Elena Vargas-Laguna ◽  
Antonio Aguilar ◽  
Miguel Ángel Gallego ◽  
Claudia Vergara ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Pyoderma Gangrenosum ◽  
Early Recognition ◽  
Skin Lesions ◽  
Unusual Event ◽  
Peripheral Ulcerative Keratitis ◽  
Appropriate Treatment ◽  
Autoimmune Conditions ◽  
Ulcerative Keratitis ◽  
Peripheral Cornea

Pyoderma gangrenosum is an unusual necrotizing noninfective and ulcerative skin disease whose cause is unknown. Ophthalmic involvement in pyoderma gangrenosum is an unusual event. Only a few cases have been reported, from which we can highlight scleral, corneal, and orbital cases. Peripheral ulcerative keratitis is a process which destroys the peripheral cornea. Its cause is still unknown although it is often associated with autoimmune conditions. Pyoderma gangrenosum should be included in the differential diagnosis of peripheral ulcerative keratitis. Early recognition of these manifestations can vary the prognosis by applying the appropriate treatment. We introduce a 70-year-old woman who suffered pyoderma gangrenosum associated with peripheral ulcerative keratitis in her left eye. The patient’s skin lesions and peripheral keratitis responded successfully to systemic steroids and cyclosporine A.

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