scholarly journals Natural polymers in photodynamic therapy and diagnosis

2021 ◽  
Vol 51 (1) ◽  
pp. 0-0
Author(s):  
Julita Kulbacka ◽  
Anna Choromańska ◽  
Zofia Łapińska ◽  
Jolanta Saczko
Keyword(s):  
Photodynamic Therapy ◽  
Natural Polymers ◽  
Therapy And Diagnosis

Spectral properties of stilbazolium merocyanines – potential sensitizers in photodynamic therapy and diagnosis

2005 ◽  
Vol 169 (2) ◽  
pp. 159-168 ◽  
Author(s):  
Ewa Staśkowiak ◽  
Alina Dudkowiak ◽  
Krzysztof Wiktorowicz ◽  
Justyna Cofta ◽  
Danuta Frąckowiak
Keyword(s):  
Photodynamic Therapy ◽  
Spectral Properties ◽  
Therapy And Diagnosis

scholarly journals Rational design of block copolymer self-assemblies in photodynamic therapy

2020 ◽  
Vol 11 ◽  
pp. 180-212 ◽  
Author(s):  
Maxime Demazeau ◽  
Laure Gibot ◽  
Anne-Françoise Mingotaud ◽  
Patricia Vicendo ◽  
Clément Roux ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Photodynamic Therapy ◽  
Block Copolymers ◽  
Rational Design ◽  
Chemical Nature ◽  
Large Range ◽  
Oxygen Species ◽  
Local Production ◽  
Natural Polymers ◽  
Intracellular Targeting

Photodynamic therapy is a technique already used in ophthalmology or oncology. It is based on the local production of reactive oxygen species through an energy transfer from an excited photosensitizer to oxygen present in the biological tissue. This review first presents an update, mainly covering the last five years, regarding the block copolymers used as nanovectors for the delivery of the photosensitizer. In particular, we describe the chemical nature and structure of the block copolymers showing a very large range of existing systems, spanning from natural polymers such as proteins or polysaccharides to synthetic ones such as polyesters or polyacrylates. A second part focuses on important parameters for their design and the improvement of their efficiency. Finally, particular attention has been paid to the question of nanocarrier internalization and interaction with membranes (both biomimetic and cellular), and the importance of intracellular targeting has been addressed.

scholarly journals Photodynamic Therapy and Diagnosis for Tumor.

1995 ◽  
Vol 33 (4) ◽  
pp. 238-245
Author(s):  
Takeshi TAKEMURA ◽  
Susumu NAKAJIMA ◽  
Isao SAKATA
Keyword(s):  
Photodynamic Therapy ◽  
Therapy And Diagnosis

Natural Hydrogels Applied in Photodynamic Therapy

2020 ◽  
Vol 27 (16) ◽  
pp. 2681-2703 ◽  
Author(s):  
Zhipan Feng ◽  
Shiying Lin ◽  
Andrew McDonagh ◽  
Chen Yu
Keyword(s):  
Photodynamic Therapy ◽  
Hyaluronic Acid ◽  
Drug Release ◽  
Three Dimensional ◽  
Controlled Drug Release ◽  
Natural Polymers ◽  
Current Review ◽  
Design Variables ◽  
Cd44 Targeting

Natural hydrogels are three-dimensional (3D) water-retaining materials with a skeleton consisting of natural polymers, their derivatives or mixtures. Natural hydrogels can provide sustained or controlled drug release and possess some unique properties of natural polymers, such as biodegradability, biocompatibility and some additional functions, such as CD44 targeting of hyaluronic acid. Natural hydrogels can be used with photosensitizers (PSs) in photodynamic therapy (PDT) to increase the range of applications. In the current review, the pertinent design variables are discussed along with a description of the categories of natural hydrogels available for PDT.

An argon-dye laser system for photodynamic therapy and diagnosis

1999 ◽  
Vol 21 (1) ◽  
pp. 103-107 ◽  
Author(s):  
J. Kübler ◽  
T. Haase ◽  
P. Kremer ◽  
M. Rheinwald ◽  
S. Kunze ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Laser System ◽  
Dye Laser ◽  
Therapy And Diagnosis ◽  
Argon Dye Laser

scholarly journals The use of 5-aminolevulinic acid and its derivatives in photodynamic therapy and diagnosis

2018 ◽  
Vol 67 (4) ◽  
pp. 113-130
Author(s):  
Anna Romiszewska ◽  
Aneta Bombalska
Keyword(s):  
Photodynamic Therapy ◽  
Aminolevulinic Acid ◽  
Protoporphyrin Ix ◽  
Photodynamic Diagnosis ◽  
Chemical Derivatives ◽  
Therapeutic Outcomes ◽  
Keywords Photodynamic Therapy ◽  
Therapy And Diagnosis ◽  
Derivatives Of ◽  
Ala Esters

5-aminolevulinic acid (5-ALA) is used as a drug in the photodynamic therapy (PDT) and photodynamic diagnosis (PDD) of cancer. Combined with irradiation at the appropriate wavelength, it is used as a photosensitizer precursor to identify/kill tumour cells. In cells, 5-aminolevulinic acid is converted to protoporphyrin IX (PpIX), which is the precursor of hemin. Internal application of 5-ALA induces the overproduction of the endogenous photosensitizer, PpIX, which can subsequently be activated by light at the appropriate wavelength. 5-ALA can be applied internally to trans-mutated areas or be injected directly into them. Chemical derivatives of 5ALA have the potential to improve bioavailability, enhance stability and lead to better therapeutic outcomes for treated patients. 5-ALA is currently the most commonly used drug in the photodynamic therapy and diagnosis (PDT/PDD) of cancers. Keywords: photodynamic therapy, photodynamic diagnosis, 5-aminolevulinic acid (5- ALA), esters of 5-aminolevulinic acid, cancer.

scholarly journals Photodynamic therapy and diagnosis: Principles and comparative aspects

2018 ◽  
Vol 233 ◽  
pp. 8-18 ◽  
Author(s):  
Jane Dobson ◽  
Genilson Fernandes de Queiroz ◽  
Jon P. Golding
Keyword(s):  
Photodynamic Therapy ◽  
Therapy And Diagnosis

Block copolymer nanoassemblies for photodynamic therapy and diagnosis

2013 ◽  
Vol 4 (11) ◽  
pp. 1431-1441 ◽  
Author(s):  
Matthew Dickerson ◽  
Younsoo Bae
Keyword(s):  
Photodynamic Therapy ◽  
Block Copolymer ◽  
Therapy And Diagnosis
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