scholarly journals Histomorphological characterization of Moringa- oleifera oil and walnut oil on cadmium induced lateral geniculate body damage in adult wistar rats (Rattus novergiccus)

2019 ◽  
Vol 3 (1) ◽  
pp. 001-007
Author(s):  
Omotoso OD ◽  
Adelakun SA ◽  
Idomeh IJ ◽  
Ogbonna E
Keyword(s):  
Wistar Rats ◽  
Moringa Oleifera ◽  
Lateral Geniculate Body ◽  
Walnut Oil ◽  
Lateral Geniculate ◽  
Moringa Oleifera Oil ◽  
Body Damage

scholarly journals Histochemical assessment of Moringa – oleifera oil and walnut oil on cadmium induced lateral geniculate body damage in developing male Wistar rats (Rattus novergiccus)

2019 ◽  
Vol 8 (2) ◽  
pp. 1593-1605
Author(s):  
O.D. Omotoso ◽  
S.A. Adelakun ◽  
B.P. Akwu ◽  
E. Ogbonna ◽  
I.J. Idomeh
Keyword(s):  
Vitamin C ◽  
Oxidative Damage ◽  
Moringa Oleifera ◽  
Lateral Geniculate Body ◽  
Walnut Oil ◽  
Lateral Geniculate ◽  
Male Wistar Rats ◽  
Group A ◽  
Moringa Oleifera Oil ◽  
The Brain

The brain is vulnerable to oxidative damage due to its high oxygen consumption. This Study investigate the effects of cadmium on the lateral geniculate body of developing male wistar rats and ameliorative potential of Moringa oleifera seed oil and walnut oil extracts. Seven groups of five animals each were used in this experiment. Group A received 3ml of 0.9% normal saline; group B received 2.5mg/kg bw of 3CdSO4.8H2O, group C received 5mg/kg bw vitamin C & 6mg/kg bw vitamin E, group D received 5mg/kg bw vitamin C & 6mg/kg bw vitamin E + 2.5mg/kg bw Cd, group E received 2.5mg/kg bw Cd + 4mg/kg bw Moringa oleifera oil, group F received 2.5mg/kg bw Cd + 4mg/kg bw walnut oil, while group G received 2.5mg/kg bw Cd + 2mg/kg bw walnut + 2mg/kg bw Moringa oleifera oil concomitantly for 3weeks. Parameter tested includes LDH, G6PD in brain tissues, SOD and GPx enzymes in brain homogenates and serum and cresyl fast violet stain in the brain tissues. Cd administration significantly increased SOD, GPx, LDH and decreased G6PD level in brain tissue and decreased their activity in serum when compared with Group A control rats. There was marked reduction and lost in the distribution of nissl substances of the studied tissues of Cd administered animals. However, administration of vitamin C & E, walnut and Moringa oleifera oil restored damaged tissues. Walnut and Moringa oleifera seed oil therefore attenuated the oxidative damage and morphological changes induced by cadmium in the lateral geniculate body of the brain of the young male wistar rats.Key Words: Lateral geniculate body, Antioxidant, Histochemical, Cadmium, Oxidative Damage

scholarly journals Study of the Antibacterial and Antioxidant Capacities of Fixed Oil of Moringa oleifera L. Cultivated in the Southwest of Algeria

2021 ◽  
Author(s):  
A. Boulal ◽  
A. Ouafiane ◽  
M. Oubiri ◽  
S. Ladjel
Keyword(s):  
Moringa Oleifera ◽  
Chemical Properties ◽  
Fatty Acid Analysis ◽  
International Standards ◽  
Antioxidant Power ◽  
Physico Chemical ◽  
Therapeutic Properties ◽  
Moringa Oleifera Oil ◽  
Solid Liquid

Background: Since time immemorial, humans have always been interested in lipids for various uses, namely food, cosmetology, medicine, etc. Many seeds, sources of oils, are increasingly studied for their nutritional and therapeutic properties. Methods: The present study aims to valorize the vegetable oil obtained from the seeds of the Moringa oleifera plant widely cultivated in the southwest of Algeria, using the solid-liquid extraction technique. In addition, the fatty acid analysis of this oil, using the gas chromatography technique. Result: An oil yield of 30.43% was obtained, revealed that it contains ten different compounds. The characterization of the oil obtained (physico-chemical properties such as organoleptic properties, density, viscosity, refractive index) proved to comply with international standards and AFNOR standards. In addition, it turned out that Moringa oleifera oil has a very interesting antioxidant power. However, this oil did not show any antibacterial activity on the strains tested.

Protective effect of Moringa oleifera oil against HgCl2-induced hepato- and nephro-toxicity in rats

2017 ◽  
Vol 28 (4) ◽  
Author(s):  
Sunny O. Abarikwu ◽  
Sussan Benjamin ◽  
Sunday Godspower Ebah ◽  
Godbless Obilor ◽  
Goodluck Agbam
Keyword(s):  
Oxidative Stress ◽  
Superoxide Dismutase ◽  
Protective Effect ◽  
Wistar Rats ◽  
Moringa Oleifera ◽  
Negative Effects ◽  
Male Wistar Rats ◽  
Moringa Oleifera Oil

Abstract:Background:Various parts of theMethods:Male Wistar rats were administered MO (1.798 mg/kg p.o.) or HgClResults:In the liver, malondialdehyde (MDA) level, glutathione (GSH), and superoxide dismutase (SOD) activities were higher whereas catalase (CAT) activity was lower in the HgClConclusions:MO decreased the negative effects of Hg-induced oxidative stress in rats.

scholarly journals Histological Assessment on Cadmium Induced Liver Damage Following Oral Administration of Moringa oleifera Oil and Anarcardium occidentale Nuts Oil in Wistar Rats

2019 ◽  
pp. 1-8
Author(s):  
O. D. Omotoso ◽  
S. A. Adelakun ◽  
O. O. Oyewo ◽  
B. T. Adediran
Keyword(s):  
Body Weight ◽  
Vitamin E ◽  
Vitamin C ◽  
Wistar Rats ◽  
Moringa Oleifera ◽  
Central Vein ◽  
Group A ◽  
Moringa Oleifera Oil ◽  
Group B ◽  
Group D

Background: Cadmium is a human carcinogen element and one of the most toxic pollutants in the environment. Present study aims at histomorphological study of some of the effects of Moringa oleifera oil and cashew (Anarcardium occidentale) nuts oil on Cadmium-induced liver damage in wistar rats. Methods: Thirty-five Wistar rats (80-180 g) were randomly selected and divided into seven groups of five rats each after acclimatization for two weeks. Group A which served as control received phosphate buffer, Group B received Cadmium only (3.5 mg/kg body weight). Group C received Vitamin C and Vitamin E; Group D received Vitamin C, Vitamin E and Cadmium. Group E received Cadmium and Moringa oleifera oil, Group F received Cadmium and Cashew nut oil and Group G received Cadmium (3.5 mg/kg body weight) and Moringa oleifera oil and Cashew (Anarcardium occidentale) nut oil. Results: Histological examination revealed normal histo-architecture of the liver, the central vein and the hepatocytes were seen clearly and there was orderly arrangement of the hepatocytes in Group A (control group). In group B, there was enlarged portal vein and there was distorted arrangement of the hepatocytes. In group C, the hepatocytes and the central vein were seen. In group D, the central vein and hepatocytes were seen though not orderly arranged. In groups E, F and G, there was restoration of the hepatocytes and the central vein was seen. Conclusion: This therefore suggests that Moringa oleifera oil and Cashew (Anarcardium occidentale) nut oil have ameliorative effects which led to the restoration of the damaged and distorted hepatocytes.

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