scholarly journals Evaluation of the use of feed additives of humic nature by indices of leukocytes in rats after combined stress

2019 ◽  
Vol 77 (1) ◽  
pp. 16-21
Author(s):  
L. Diachenko ◽  
L. Stepchenko
Keyword(s):  
Body Weight ◽  
Vitamin E ◽  
Feed Additives ◽  
The Body ◽  
Stress Factors ◽  
Feed Additive ◽  
Control Group ◽  
Combined Stress ◽  
Active Forms Of Oxygen ◽  
Functional Changes

In response to the action of stress factors of different genesis in a living organism, a cascade of adaptive responses, which can neutralize functional disorders of homeostasis, is triggered. Combining the effects of various stress factors can cause excessive formation and accumulation of active forms of oxygen, which entails a number of pathological conditions that create the preconditions for the development of a large number of diseases. One of the indicators of the development of adaptation and the integral indicator of the body's state is the blood system, especially the leukocytic formula, whose redistribution makes it possible to analyze the nature of the effect and estimate the intensity of adaptive processes in the body due to functions that perform different forms of leukocytes. Leukocyte indices in which the parameters of the leukocyte formula were used, allow assessment of the degree of endogenous intoxication, the development of resistance and the character of cellular immunity for the influence of stress factors on the organism of animals and humans.The article considers the possibility of evaluating the preventive effect of natural antioxidants of humic nature on indices of leukocytes on the organism of rats after the influence of combined water-immobilization stress (WICS). for this, the animals were divided into five groups of 6 animals: 1- group of intact animals (control); 2-5 – experimental groups. Animals of all experimental groups were additionally received orally, individually with the help of a probe for 18 days, water, feed additives "Humilid" (at 5 mg / kg of body weight per active ingredient), "Eco-Impulse Animal" (at a rate of 2.5 mg / kg body weight) and vitamin E (at a rate of 50 mg / kg body weight). In animals, 2, 3, 4 and 5 groups simulated stress. It has been established that the effects of water-immobilization combined stress on blood of rats lead to the growth of cells of the leukocyte series, mainly due to the increase of eosinophils and rod-neutron neutrophils. The use of natural antioxidant, a feed additive "Humilid" in the pre-season period causes a decrease in the number of leukocytes by 41% compared to values in animals that received purified water during this period and did not differ from those in intact animals. The change in leukocyte indexes indicates functional changes in the body and the presence of a neutrophilic shear on the background of WICS in rats. Also, the effect of WICS leads to the release of the younger forms of neutrophils in the bloodstream, an increase in both the percentage of eosinophils and the quantitative. For preventive use of feed additives of humic nature, "Humilid" and "Eco-Impulse Animal" and vitamin E, the studied parameters are close to the values of the control group.

scholarly journals «Energosil» in the diets of replacement gilts

2019 ◽  
Vol 20 (2) ◽  
pp. 153-162
Author(s):  
A. A. Suvorov ◽  
в Sh. Gayirbegov ◽  
A. S. Fedin ◽  
A. M. Guryanov
Keyword(s):  
Body Weight ◽  
Live Weight ◽  
Feed Additives ◽  
The Body ◽  
Feed Additive ◽  
Control Group ◽  
Practical Training ◽  
Optimal Dosage ◽  
Growth Energy ◽  
Experimental Group

The article gives scientific substantiation of using silicon-containing new feed additive “Energosil” for replacement gilts. The studies were conducted in pig-breeding complex of the Center for Practical Training of Agricultural Specialists in Mordovia Republic. There were three experimental groups of replacement gilts (10 animals each). The effect of various dosages of Energosil (5.0, 7.5, and 10 mg per kg of body weight) on digestibility, nutrient utilization, and animal growth energy was studied. The most optimal dosage of a new feed additive in their rations was revealed, which constituted 5 mg / kg of the animal live weight. It was established that the animals from the first experimental group, who received silicon-containing feed additives of this amount digested the nutrients of the diet better than their counterparts from the other groups. Compared to the control group, the digestibility of dry matter increased by 3.62% (p<0.05), organic matter by 3.29% (p<0.01), crude protein by 4.09% (p<0.001), fat by 4.30% (p<0.01), cellulose by 3.79% (p<0.01) and nitrogen-free extractives by 2.03% (p>0.05).Replacement gilts of the first experimental group, who were given Energosil in the amount of 5 mg / kg body weight in addition to the basic ration, retained nitrogen in their bodies by 17.1%, calcium by 55.9% and phosphorus by 69.7% more than their counterparts from the control group. It contributed to an increase in body weight of gilts from the first group compared to control counterparts by 10.8%. Increased dosages of Energosil (7.5 and 10 mg / kg body weight) also had a better effect on the growth energy of gilts compared with the control group. The feed additive in the amount of 7.5 mg kg of animal  live weight contributed to an increase in animal weight compared with control counterparts by 6.21 kg or 4.8% (p<0.05), with a third experimental group by 4.4 kg or by 3.4% (p<0.05). When given Energosil in the dosage of 10 mg/kg, the body weight of gilts from the third experimental group was higher by 1.81 kg or 1.4% (p> 0.05) compared with the control counterparts.

scholarly journals The Influence of Highly Dispersed Metal Forms on Calcium and Phosphorus Metabolism in Polygastric Animals

2022 ◽  
Author(s):  
Makaeva Ayna Maratovna ◽  
Sizova Elena Anatolevna ◽  
Atlanderova Ksenya Nikolaevna
Keyword(s):  
Feed Additives ◽  
The Body ◽  
Feed Additive ◽  
Utilization Rate ◽  
Control Group ◽  
Ruminal Fluid ◽  
Group I ◽  
Calcium And Phosphorus ◽  
Group Ii ◽  
Experimental Group

Determining which forms of mineral feed additives can increase farm animal productivity is a key area of research. This study assessed the mineral composition of ruminal fluid and the effectiveness of calcium and phosphorus used by animals after the introduction of finely dispersed particles (FDP) of SiO2 (group I) and FeCo (group II) with a hydrodynamic radius of 109.6 ± 16.6 and 265 ± 25 nm, respectively. The deposition and use of calcium and phosphorus in the body of the experimental animals exceeded the control values. In group I, 30.8% more calcium was deposited (p ≥ 0.05), and in group II, the value was 30.3% (p ≥ 0.01). In the experimental groups, the calcium utilization rate was 27.3% higher in group I (p ≥ 0.05), and 28.2% higher in group II (p ≥ 0.01) compared to in the control. Phosphorus deposition was 34% higher (p ≤ 0.01) in experimental group I and 6% higher in experimental group II, compared with the control. Group I had a high utilization rate of phosphorus from the feed (with a 29% difference compared to the control). Comparison of the experimental groups revealed that the introduction of SiO2 FDP promoted an increase in the concentration of silicon, phosphorus, and calcium in the ruminal fluid. The introduction of FeCo FDP was accompanied by a decrease in the concentration of iron and cobalt in the ruminal fluid. Thus, the use of feed additive in finely dispersed form in the diet of animals was accompanied by an increase in the use of calcium and phosphorus by the animal’s body, which is advisable when intensifying milk and meat productivity. The obtained results require further research. Keywords: finely dispersed forms of microelements, ruminants, calcium and phosphorus exchange, feeding

scholarly journals System of antioxidant protection of the body of piglets under the action of feed additive “Sylimevit”

2021 ◽  
Vol 23 (104) ◽  
pp. 10-17
Author(s):  
L. V. Vyslotska ◽  
B. V. Gutyj ◽  
O. V. Kozenko ◽  
V. I. Khalak ◽  
M. V. Chornyj ◽  
...  
Keyword(s):  
Body Weight ◽  
Antioxidant Defense System ◽  
Feed Additives ◽  
The Body ◽  
Biologically Active ◽  
Feed Additive ◽  
Free Access ◽  
Direct Acting ◽  
Active Substances ◽  
Technological Stress

One of the conditions for obtaining high-quality pig products is the use of feed additives, which contain all the necessary biologically active substances, eliminating their deficiency in feed and acting as catalysts for metabolic processes in pigs. That is why the aim of the study was to study the effect of feed additive “Sylimevit” on the enzymatic and non-enzymatic parts of the antioxidant system of piglets after weaning. Two groups of piglets were formed – control and experimental, in the amount of 10 individuals in each group, selected on the principle of analogues – age, breed and body weight. During the weaning period, the piglets were kept under the sow in special machines, had constant access to the mother, and from the age of 5 days – free access to concentrated feed. Feeding of animals was carried out in accordance with the norms for a given age of pigs. Prior to the study, a clinical and physiological examination of the piglets was performed. Their general condition and activity when eating food were taken into account. On the 28th day of life, the piglets were weaned from the sow and regrouped from different nests in order to be further maintained during the period of fattening and rearing with a change in the structure of the diet, which served as technological stress for the animals. From the age of 5 days, piglets of all groups were fed pre-starter feed. Piglets of the experimental group, from 21 to 40 days of age, were additionally fed the feed supplement “Sylimevit” at a dose of 100 mg/kg body weight per day. Feeding piglets Silimevit feed enhances their antioxidant status. The use of this feed additive in piglets contributed to the activation of both enzymatic and non-enzymatic parts of the antioxidant defense system of piglets after weaning, as indicated by an increase in blood 35-day-old piglets superoxide dismutase activity by 26.9 % (P < 0.001), catalase – 41.1 % (P < 0.001), glutathione peroxidase – by 52.7 % (P < 0.05), glutathione reductase – by 53.5 % (P < 0.05), the content of reduced glutathione – by 75 % (P < 0.001). This is due to the fact that silimevit contains active substances such as milk thistle and vitamins, which are strong direct-acting antioxidants and directly interact with free radicals and reactive oxygen species.

scholarly journals The effect of lycopene and vitamin E on the growth performance, quality and oxidative stability of chicken leg meat

2011 ◽  
Vol 56 (No. 12) ◽  
pp. 536-544 ◽  
Author(s):  
M. Englmaierová ◽  
I. Bubancová ◽  
T. Vít ◽  
M. Skřivan
Keyword(s):  
Body Weight ◽  
Vitamin E ◽  
Oxidative Stability ◽  
Dry Matter ◽  
Growth Traits ◽  
Cholesterol Content ◽  
The Body ◽  
Control Treatment ◽  
Dietary Vitamin ◽  
Control Group

&nbsp;A 2 &times; 3 factorial design experiment was conducted to evaluate the effect of adding lycopene <br />(0 and 75 mg/kg) and vitamin E (0.50 and 100 mg/kg) to the diet of chickens. Moreover, the study investigated growth traits, oxidative stability and chemical composition of leg meat and the vitamin content of meat and liver. The study was conducted using five hundred and forty Ross 308 male broilers that were assigned to one of the six dietary treatments. Significant interactions between lycopene and vitamin E additions affected the body weight of 21-days-old chickens (P = 0.005), the malondialdehyde content in fresh leg meat (P &lt; 0.001) and leg meat stored for 3 days at temperatures of 2.5 to 4&deg;C (P = 0.032), the cholesterol content in leg meat (P &lt; 0.001) and the lycopene content in liver (P = 0.006). The chickens with the highest body weight were fed 75 mg/kg of lycopene and 50 mg/kg of vitamin E. The vitamin E supplement increased the oxidative stability of fresh and stored leg muscle (P &lt; 0.001). The lowest mean cholesterol value (3.49 g/kg of dry matter) was found out in the meat from broilers that were fed 75 mg/kg of lycopene in contrast to broilers fed the control treatment without lycopene (3.93 g/kg of dry matter). Dietary vitamin E significantly reduced the fat content (P = 0.033) and increased the ash content of&nbsp;leg meat. The highest lycopene concentration in liver (2.82 mg/kg of dry matter) was in chickens that were fed the highest levels of vitamin E and lycopene in contrast with the control group (0.28 mg/kg of dry matter). &nbsp;

scholarly journals Administration of garlic and neem in broiler diet for safe meat production

2020 ◽  
Vol 48 (2) ◽  
pp. 116-126
Author(s):  
R Islam ◽  
MM Hossain ◽  
F Nargis ◽  
ME Hossain
Keyword(s):  
Body Weight ◽  
Basal Diet ◽  
Feed Additives ◽  
The Body ◽  
The Other ◽  
Control Group ◽  
Meat Production ◽  
Broiler Chicks ◽  
Treatment Groups ◽  
Broiler Production

This study was conducted to observe the effect of different administration method of garlic and neem on growth performances, feed efficiency and serum biochemical parameters for safe broiler production. The experiment was done for a period of 32 days with 384 one-day-old straight run broiler chicks. The broiler chicks were divided into six groups each of 64 birds and replicated to four subgroups each of 16 birds. The dietary groups were; control (basal diet; no additives), antibiotic (basal diet + antibiotic), garlic in feed (basal diet + 0.25% garlic powder), garlic in water (basal diet + garlic extracts), neem in feed (basal diet + 0.25% neem powder) and neem in water (basal diet + neem extracts). Results showed that the body weight and body weight gain increased significantly (P<0.05) in both the garlic and neem groups compared to the control group. Feed intake was not different (P>0.05) among the treatment groups. Garlic in feed and water and neem in feed groups showed better FCR (P<0.05) compared to the other treatment groups. There were no significant (P>0.05) difference in meat yield, bone development and dressing parameters except head and gizzard in different dietary groups. Supplementation of garlic with feed and water significantly (P<0.05) decrease cholesterol, triglyceride and LDL compared to the other groups. However, both the garlic and neem groups showed numerically higher HDL compare to the control group. There were no 0significant (P>0.05) differences in serum glucose and GPT among different treatment groups. GOT was significantly (P<0.05) lower in neem groups than that of garlic and antibiotic groups. Additive groups showed higher profitability than control group. Based on the results of the study, it may be suggested that the garlic and neem could be used both in feed and water as potential feed additives for safe broiler production. Bang. J. Anim. Sci. 2019. 48 (2): 116-126

scholarly journals Features of protein metabolism in the body of broiler chickens when using the feed additive Peak-Antistress in the diet

2020 ◽  
pp. 103-110
Author(s):  
A. V. Mitfakhutdinov ◽  
E. R. Saifulmuliukov
Keyword(s):  
Broiler Chickens ◽  
Protein Composition ◽  
Feed Additives ◽  
The Body ◽  
Feed Additive ◽  
Control Group ◽  
Protein Accumulation ◽  
White Meat ◽  
Scientific Publications ◽  
Experimental Group

Scientific publications describe the positive effect of feed additives and pharmacological complexes on metabolic processes in the body of broiler chickens, in particular, on the protein composition of the blood, meat productivity and protein accumulation in meat. The Peak-Antistress feed additive developed at the Department of Morphology, Physiology and Pharmacology of the South Ural State Agrarian University allows to reduce the technological load on the poultry body by stimulating the general metabolism and complex antioxidant action. Experiments on the use of the feed additive Peak-Antistress were carried out on broiler chickens of the final hybrid of the Arbor Acres cross in an industrial-type poultry farm with floor technology. The poultry was divided into three groups of 6,000 chickens each and kept in one workshop in separate sections. The control group received the main diet, the 1st experimental group received the main diet and feed additive at a dose of 1269 g / t of feed 5 days before slaughter, the 2nd experimental group received the main diet and feed additive at a dose of 1693 g / t of feed 5 days before slaughter. Slaughter of broiler chickens was carried out according to the technological instructions of the enterprise on the 38th day. Against the background of the use of the feed additive in the experimental groups of broiler chickens, stimulation of protein metabolism was observed, as evidenced by an increase in total protein in the blood by 7.9–20.1%, an increase in the level of protein in white meat by 0.1–0.3%, and a tendency to an increase in amino acids in white meat protein by 0.2–12.3%.

scholarly journals The effect of different doses of probiotic feed additives on hematologic indices and morphological structure of individual pig internal organs

2020 ◽  
Vol 3 (1) ◽  
pp. 13-20
Author(s):  
M. Zhyla ◽  
N. Shkodyak ◽  
G. Kotsyumbas ◽  
Y. Stronskyi ◽  
O. Sobodosh ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Feed Additives ◽  
The Body ◽  
Feed Additive ◽  
Control Group ◽  
Histological Structure ◽  
Metabolic Processes ◽  
Morphological Studies ◽  
Significant Difference ◽  
White Breed

In order to improve the digestibility and absorption of feed, metabolic processes, growth and development of animals, increase the resistance of the body immunomodulatory agents, probiotics, prebiotics, combined enzyme-probiotic feed additives are widely used. The purpose of our work was to conduct comparative clinical trials of the effectiveness of the probiotic feed additive Probion-forte in terms of productivity, blood indices and histological structure of individual internal  pigs organs during fattening. The researches were carried out on 120 piglets of big white breed at the age of 28 days, which were divided into 4 groups with 30 units in each one. The probiotics were added to feed in different concentrations in order to determine their efficiency and examine influence on piglets organism: the first group was given probiotic Probion-forte in dose of 1.0 g/kg (10 weeks); the second one – Probion in dose of 1.0 g/kg (6 weeks) and 0.5 g/kg (4 weeks); the third one was given probiotic Bio Plus 2B in dose of 0.4 g/kg for 10 weeks; and the fourth one was a control group. The compound feed was provided according to norms recommended for big white breed taking into account age. On the 42nd day (6 weeks) and on the 70th day of test 10 units were selected for haematological, pathomorphological and microbiological tests. The productivity of animals of all studied groups was evaluated by the average daily gains, safety, feed conversion and slaughter output. The stabilized with EDTA piglets’ blood was used for morphological studies, and blood serum – for biochemical studies. The clinical trials have shown that the application of Probion-forte, as a feed additive for fattening of piglets within 10 weeks after weaning, did not cause adverse reactions, was well tolerated by animals and contributed to the improvement of the processes of erythropoiesis and leucopoiesis, increased of serum total protein content. The increasing activity of serum transaminases indicated more intense metabolic processes in experimental animals’ organism, which was confirmed by increase in average daily weight gains and slaughter output compared to control. In the microscopic examination of the thymus, spleen, lymph nodes, intestines, liver, the characteristic histological structure of the organs was preserved and indicated their active morphofunctional state throughout the study period. Morphometrically the increase in the height of the villi in the duodenum and the size of the thymus lobes in piglets, which were fed with probiotic feed additives was established. The efficiency and appropriateness of the application of these products was confirmed in the first and second experimental groups. However, the most significant difference was observed in piglets fed with Probion-forte for 10 weeks at a dose of 1.0 g/kg of feed.

scholarly journals Influence of various levels of valin in the mixed fodder on the carcass composition of quails

2017 ◽  
Vol 19 (79) ◽  
Author(s):  
M. Sychov ◽  
T. Golubeva ◽  
V. Kovalchuk ◽  
Y. Poznyakovskiy
Keyword(s):  
Body Weight ◽  
Large Body ◽  
Carcass Composition ◽  
Feed Additives ◽  
The Body ◽  
Control Group ◽  
Feed Conversion ◽  
Experimental Scheme ◽  
National University ◽  
Effective Level

The article presents the expediency of using valine in the feeding of growing quails of meat direction of productivity. The studies were conducted in the conditions of research laboratory of feed additives of National University of Life and Environmental Sciences of Ukraine. The experiment was conducted with growing Pharaoh quails. It was selected 500 daily quails. Birds were placed in 20 cages with 25 heads in each. In the formation of analog groups, the body weight of the birds was taken into account. Quails were fed full-fledged mixed fodder, which was balanced by energy and other nutrients. The feed for the quails of the control group contained the natural level of valine, and the experimental groups – additionally L-valine according to the experimental scheme. Observed a relationship between the level of valine in feed and feed conversion (R2 = 0.7359). The most effective level of valine in mixed fodder for quail, which is grown for meat, to obtain a sufficiently large body weight with a low level of feed intake per unit of growth is at 1– 21-day age – 1.68% and at 22– 35-day age – 1.23%.

scholarly journals Influence of phytogenic feed additives and prebiotic in vegetable protein based diet on broiler performance

2018 ◽  
Vol 28 (4) ◽  
pp. 323-330 ◽  
Author(s):  
HR Tanzim ◽  
GB Das ◽  
M Ahmad ◽  
M Barua ◽  
K Islam
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Feed Intake ◽  
Vegetable Protein ◽  
Experimental Period ◽  
Feed Additives ◽  
Feed Additive ◽  
Control Group ◽  
Feed Conversion ◽  
Broiler Performance

This study was conducted to determine the effect of phytogenic feed additive and prebiotic on vegetable protein base diet in broiler performance.  A total of 90 chicks (Cobb-500) were weighted and randomly assigned to the three treatment groups (To, T1 and T2) and supplemented with either phytogenic feed additives or prebiotic and reared for 28 days. Data on live body weight, body weight gain, feed intake and feed conversion (FC) were taken at weekly interval. Results revealed that significant (P<0.05) increase in live body weight of broilers was evident in both phytogenic feed additive and prebiotic supplemented groups comparing to the control group at 4th weeks of age. No significant (P>0.05) differences were found in live weight gain among the treatment groups on weekly intervals along the whole experimental period. However, significant differences (P<0.05) were evident on cumulative weight gain at 3rd and 4th weeks of age. In case of feed intake at the age of 3rd and 4th weeks, significant (P<0.05) differences were obtained with decreased feed intake in both phytogenic feed additive and prebiotic supplemented groups comparing to the control group. In case of feed conversion (FC), there were significant (P<0.05) differences among the groups on 1st week and 4th week of age. Best FC was accounted for prebiotic supplemented group along the whole experimental period. The survivability rates were 96.67%, 100% and 100% in control group, phytogenic feed additive and prebiotic supplemented group respectively. Results finally showed that vegetable protein when supplemented with phytogenic prebiotic feed additives and prebiotic c an additive beneficial effect on performance of when compared to non-supplemented control diet. So, ration using vegetable protein mixed with phytogenic feed additives or prebiotic can be recommended for broiler.Progressive Agriculture 28 (4): 323-330, 2017

scholarly journals Morphological blood indices of bulls in experimental chronic cadmium toxico-sis

2018 ◽  
Vol 20 (88) ◽  
pp. 108-114 ◽  
Author(s):  
Y. Y. Lavryshyn ◽  
B. V. Gutyj ◽  
O. R. Palyadichuk ◽  
V. Y. Vishchur
Keyword(s):  
Body Weight ◽  
Cadmium Chloride ◽  
Cadmium Toxicity ◽  
The Body ◽  
Erythrocyte Membranes ◽  
Control Group ◽  
Destructive Effect ◽  
Active Forms Of Oxygen ◽  
Young Cattle ◽  
Experimental Group

The article presents the results of research on the influence of cadmium load on the body of young cattle. The purpose of the work was to investigate morphological indices of bulls blood during the development of experimental chronic cadmium toxicity. According to the morphological analysis of the quantitative and qualitative composition of blood, it is possible to deem objectively about the functional state of the hematopoietic system of the organism of young cattle. The research was  conducted (on the basis of the farm of the village of Ivanivtsi, Zhydachiv rayon of the Lviv region) on 10 bulls of six months old, Ukrainian black-and-white milk breed, which were formed in 2 groups of 5 animals in each: control and experimental. Bulls of the control group were in the usual diet. Bulls of the experimental group were fed with a feed with cadmium chloride at a dose of 0.04 mg/kg body weight of the animal. It has been established that feeding Bulls with cadmium chloride in a dose of 0.04 mg/kg of body weight contributed to a decrease in hemoglobin to 84.5 ± 1.60 g/l and an increase in the content of methemoglobin to 5.2 ± 0.099%. The decrease in hemoglobin levels is due to the toxic effect of cadmium on erythrocytes, resulting in damage to erythrocyte membranes and increased content of methemoglobin. Formation of methemoglobin in bull blood during cadmium loading occurs as a result of oxidation of hemoglobin with the formation of superoxide anion, which in turn triggers (begins) free radical processes and exerts a destructive effect on cell membranes, as well as initiates the appearance of other active forms of oxygen. Feeding calcium cadmium chloride in a dose of 0.04 mg/kg contributed to a decrease in the number of erythrocytes in their blood. At day 20 of the experiment, the number of erythrocytes decreased by 14% relative to the control group. Decreasing the number of erythrocytes in the blood of young cattle may have been due to the inhibition of their production in the bone marrow. An important morphological indicator of blood is the determination of the average content of hemoglobin in one erythrocyte, which indicates the saturation of erythrocyte with hemoglobin. It was found that the average hemoglobin content in one erythrocyte of the bulls of the experimental group increased by 11.4 and 13.9% for 5 and 10 days. According to the results of the research, the reduction of the hematocrit values in the experimental group of bulls was detected at 10, 15 and 20 days of the experiment. A significant increase in the number of leukocytes in the blood of the bulls of the experimental group was observed at 15 days of the experiment, according to the control group indicators, it increased by 12%.

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