scholarly journals Ultrasound elastography as a method of emergency diagnosis of the first signs of transient ischemia of the lower limbs in diabetic foot syndrome

2016 ◽  
Vol 97 (6) ◽  
pp. 860-864
Author(s):  
R I Fatykhov ◽  
I V Klyushkin ◽  
Yu A Klyushkina ◽  
N A Minnemullin ◽  
M N Nasrullaev
Keyword(s):  
Young’S Modulus ◽  
Shear Wave ◽  
Diabetic Foot ◽  
Modulus Of Elasticity ◽  
Young's Modulus ◽  
Shear Wave Elastography ◽  
Lower Limbs ◽  
Diabetic Foot Syndrome ◽  
Transient Ischemia ◽  
Young’S Modulus Of Elasticity

Aim. Evaluate the data of elastography characteristic for the first signs of transient ischemia of lower limbs in diabetes foot syndrome.Methods. In Kazan city clinical hospital №7 measurement of Young’s modulus of elasticity was performed in 12 patients with transient ischemia in diabetic foot syndrome. The methods and assessment of parameters typical for soft tissues of lower limbs we have developed earlier (patent «Method of elastography diagnosis of tissue changes in diabetic foot syndrome»). Color duplex scan of the arteries was performed according to standard method with the use of 5 to 10 MHz linear array probe starting from distal parts of limbs. Measurement of ultrasound density was performed with the use of shear wave elastography with 4 to 15 MHz wide-band linear probe. All parameters were measured in real time mode.Results. Increase of elastomeric index (Young’s modulus of elasticity) to 23.74±2.34 kPa (93,49±1,26%) in the distal segment of the lower extremity (on the foot) is associated with development of transient disorders in the lower limbs in diabetic foot syndrome, which is not always detected with invasive methods of diagnosis.Conclusion. Shear wave elastography is recommended for emergency medical care in diabetic foot syndrome; patients after being diagnosed with type 2 diabetes should dynamically monitor microcirculation of lower limbs that will decrease the risk of need of surgical treatment.

THE INFLUENCE OF SEX HORMONES ON THE BONY CHANGES OCCURRING IN PARALYSED LIMBS

1954 ◽  
Vol 11 (1) ◽  
pp. 66-70 ◽  
Author(s):  
J. A. GILLESPIE
Keyword(s):  
Young’S Modulus ◽  
Sex Hormones ◽  
Modulus Of Elasticity ◽  
Young's Modulus ◽  
Bending Moment ◽  
Breaking Point ◽  
Total Weight ◽  
Breaking Stress ◽  
Young’S Modulus Of Elasticity ◽  
Ash Weight

SUMMARY 1. Paralysis, produced in young male rats by avulsion of peripheral nerves, resulted in a highly significant reduction in the total weight, ash weight, ash percentage, X-ray density and bending moment at the breaking point, of the bones of the affected limb. The breaking stress was significantly reduced, but Young's modulus of elasticity was unaltered. 2. Certain of these changes were modified by treatment with sex hormones. Both oestradiol and testosterone significantly reduced the difference between the bones of the normal and paralysed limbs in respect of total weight, ash weight and bending moment at the breaking point. 3. Treatment with oestradiol significantly increased both the ash percentage and Young's modulus of elasticity, the increase affecting equally the bones of the normal and paralysed limbs. Testosterone treatment did not significantly affect either of these properties, and neither hormone affected the breaking stress.

The impact of body position and exercise on the measurement of liver Young’s modulus by real-time shear wave elastography

2021 ◽  
pp. 1-10
Author(s):  
Xia Jiang ◽  
Li Li ◽  
Hong-Yuan Xue
Keyword(s):  
Healthy Volunteers ◽  
Real Time ◽  
Young’S Modulus ◽  
Shear Wave ◽  
Supine Position ◽  
Young's Modulus ◽  
Body Position ◽  
Shear Wave Elastography ◽  
Lateral Position ◽  
Left Lateral Position

BACKGROUND: In the past ten years, liver biopsies have been used as a method to accurately diagnose the stage of fibrosis. OBJECTIVE: This study aimed to evaluate whether body position and exercise affect the measurement of liver Young’s modulus of healthy volunteers by real-time shear wave elastography (RT-SWE). Methods: RT-SWE was used to measure liver Young’s modulus in the supine and left lateral positions of 70 healthy volunteers at rest and measure the liver Young’s modulus in the lying position before exercise, and at zero, five, and ten minutes of rest after exercise. RESULTS: The liver Young’s modulus in the left lateral position was significantly higher than in the supine position (P< 0.05), and the measured value in the supine position was more stable than the left lateral position. The liver Young’s modulus measured at zero minutes after exercise was significantly higher than that measured before exercise (P< 0.05). The liver Young’s modulus measured at five minutes after exercise was significantly higher than that measured at zero minutes after exercise (P<0.05) and was not statistically different from the measured value before exercise (P> 0.05). The liver Young’s modulus measured at ten minutes after exercise was significantly higher from that measured at zero minutes after exercise (P< 0.05) and was not statistically different from the measured value at five minutes after exercise (P> 0.05). CONCLUSION: Body position and exercise have a significant impact on the measurement of liver Young’s modulus. It is recommended that the examinees take a supine position during the measurement, and measurement should be conducted at least ten minutes after exercise.

Effects of Vertebral Body Changes on Cervical Spine Load Sharing

2002 ◽  
Author(s):  
Jiangyue Zhang ◽  
Narayan Yoganandan ◽  
Frank A. Pintar
Keyword(s):  
Cervical Spine ◽  
Young’S Modulus ◽  
Vertebral Body ◽  
Modulus Of Elasticity ◽  
Young's Modulus ◽  
Compressive Force ◽  
Axial Compressive Force ◽  
Inferior Surface ◽  
Biomechanical Behavior ◽  
Young’S Modulus Of Elasticity

The objective of the study was to determine the effects of changes in the Young’s modulus of elasticity of the cancellous bone that occur due to the ageing process on the biomechanical behavior of the cervical spine. An anatomically accurate three-dimensional (3-D) nonlinear finite element model of the C4-C5-C6 cervical spinal unit was used. The inferior surface of the C6 vertebrae was fixed in all degrees of freedom, and external loads were applied to the top surface of the C4 vertebra. The model was exercised under an axial compressive force of 754 N. In addition, flexion and extension bending moments of 3.44 Nm were applied individually to the model. The effects of ageing on bone strength were simulated by decreasing the Young’s modulus of elasticity from 100 MPa in the healthy spine to 40 MPa in the degenerated spine. The degenerated spine was found to be more flexible than the healthy spine. In addition, the degenerated spine responded with increased forces in the outer anterior and posterior regions of the vertebral body. Furthermore, forces in the facet joints increased in the degenerated spine. In contrast, the middle region of the disc showed decreased forces. These increases in the forces leading to stress risers may explain the occurrence of osteophytes in the spine with age.

scholarly journals Young’s modulus of elasticity of Schlemm’s canal endothelial cells

2009 ◽  
Vol 9 (1) ◽  
pp. 19-33 ◽  
Author(s):  
Dehong Zeng ◽  
Taras Juzkiw ◽  
A. Thomas Read ◽  
Darren W.-H. Chan ◽  
Matthew R. Glucksberg ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Young’S Modulus ◽  
Modulus Of Elasticity ◽  
Young's Modulus ◽  
Schlemm’S Canal ◽  
Schlemm's Canal ◽  
Young’S Modulus Of Elasticity
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