scholarly journals Low intensity shock wave therapy for erectile dysfunction: 6 months followup results

2017 ◽  
Vol 7 (3) ◽  
pp. 5-13
Author(s):  
Igor A Korneyev ◽  
Ivan V Telegin ◽  
Ivan V Davydov ◽  
Artem V Matveev ◽  
Dmitrij V Rubanov ◽  
...  

Introduction. Low intensity extracorporeal shock wave therapy (ESWT) is a novel promising method of treatment for men with erectile dysfunction (ED). The efficacy of ESWT is not clearly determined and need further investigation. Aim of the study: To investigate 6 months followup efficacy and safety results from ESWT trial in patients with ED. Patients and methods. This open-label, longitudinal observational study investigated 6 months followup results in 19 men (mean age = 59.5 years) with organic ED (including 6 (32%) patients with type 2 diabetes mellitus and 6 (32%) patients after nerve-sparing radical prostatectomy) treated with 5-session weekly ESWT protocol using DornierAries delivery system (7500 shock waves, 1500 each session, 4 Hz). Information about adverse events was recorded. Effectiveness was assessed according to the International Index of Erectile Function and Sexual Health Inventory for Men after the 5th ESWT session and also in 1, 3 and 6 months. Results. No patient reported treatment-related adverse events. In 12 (63%), 11 (57%), 11 (57%) and 9 (47%) patients IIEF increased after the 5th ESWT session (also in 2 (33%) men with ED caused by radical prostatectomy), and in 1, 3, 6 months after treatment respectively, so the mean IIEF score in the group has become higher (p = 0.003, p = 0.050, p = 0.022, р > 0.1 respectively) as well as the IIEF general satisfaction domain score (p = 0.006 и p = 0.014, р = 0.011 и p = 0.028, respectively). Mean SHIM score growth was significantly higher after the 5th ESWT session only (р = 0.020), also in patients with diabetic ED (р = 0.041). Individual variability of both IIEF and SHIM scores after treatment was high, with IIEF lower in patients with advanced age (р = 0.015). Conclusions. In 6 months followup ESWT was safe in all and effective in many patients with ED. High individual variability of treatment efficacy needs further evaluation. (For citation: Korneyev IA, Telegin IV, Davydov IV, et al. Low intensity shock wave therapy for erectile dysfunction: 6 months followup results. Urologicheskie vedomosti. 2017;7(3):5-13. doi: 10.17816/uroved735-13).

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Héctor A. Corredor Ayala ◽  
José Pablo Saffon Cuartas ◽  
Diana Cerquera Cleves

Objective. The aim of this study is to evaluate the response to low-intensity extracorporeal shock wave therapy in a group of patients with organic vascular erectile dysfunction. Materials and Methods. This is an observational retrospective study. The researchers reviewed 710 patients with a clinical diagnosis of organic vascular erectile dysfunction (ED) of more than 3-month duration from male sexual health clinics of the Boston Medical Group from 12 cities in Spain and 4 in Mexico. Patients received 5 outpatient shock wave therapy sessions. They were evaluated with the erection hardness score (EHS) before the first session (n = 710), at the end of the last session (n = 710), and one month after the last session (n = 412). Results. In the first examination, the EHS improved in 43.1% (306/710) of subjects compared to the baseline measurement and ability to penetrate increased from 26.8% to 44% (p<0.0001). In the second examination, the ability to penetrate was 37.9%, lower than in the first (p=0.042) but higher than the baseline (p=0.0001). Conclusions. The results suggest that the shock wave therapy with or without concomitant treatments improved the quality of erections in patients with erectile dysfunction treated in specialised male sexual health clinics. This trial is registered with NCT03237143.


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