The effect of rivaroxaban low doses on the stable angina of the II–III functional class clinical manifestations and the quality of life in patients with ischemic heart disease

Kardiologiia ◽  
2021 ◽  
Vol 61 (9) ◽  
pp. 47-51
Author(s):  
A. A. Nekrasov ◽  
E. S. Timoshchenko ◽  
T. A. Nekrasova ◽  
M. V. Timoshchenko ◽  
A. V. Suleimanova
Keyword(s):  
Quality Of Life ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Acetylsalicylic Acid ◽  
Stable Angina ◽  
Clinical Manifestations ◽  
Functional Class ◽  
Ischemic Heart ◽  
Short Acting

Aim      To evaluate the effect of low-dose rivaroxaban on quality of life of patients and clinical manifestations of functional class (FC) II-III stable angina.Material and methods  26 patients with ischemic heart disease (IHD) with FC II-III stable angina, who were newly prescribed rivaroxaban 2.5 mg twice a day in combination with acetylsalicylic acid 75-100 mg, were followed for 10 weeks. During the first (before the beginning of treatment) and the last weeks of study, patients kept diaries, in which they reported angina attacks and short-acting nitrate intake, filled in an angina questionnaire (SAQ), and underwent electrocardiogram (ECG) Holter monitoring (HM).Results The treatment was associated with decreases in the frequency of angina attacks (by 19.5 %; р=0.027) and the number of taken short-acting nitrate pills (by 17.1 %; р=0.021) and an improvement of quality of life according to stability scales (р=0.042). Data from ECG HM showed decreases in the number and duration of ischemic episodes (p≤0.05).Conclusion      The treatment of IHD patients with rivaroxaban 2.5 mg twice a day in combination with acetylsalicylic acid 75-100 mg for 2 mos. was associated with decreased frequency of angina attacks, reduced requirement for short-acting nitrate, and with improvement of quality of life.

Comparison of the effect of 12- and 24-session cardiac rehabilitation on physical, psychosocial and biomedical factors in ischemic heart disease patients

2020 ◽  
Vol 41 (1) ◽  
Author(s):  
Masoumeh Sadeghi ◽  
Abdullah Izadi ◽  
Mohammad Mahdi Hadavi ◽  
Mohammad Rafati Fard ◽  
Hamidreza Roohafza
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Cardiac Rehabilitation ◽  
Ischemic Heart ◽  
Life Questionnaire ◽  
Short Term ◽  
Significant Difference

AbstractBackgroundCardiac rehabilitation (CR) is a key component of effective care for patients with a wide spectrum of cardiac problems. It seems that the short-term provision of these services can facilitate their use and meeting of related needs for patients participating in the CR programs.Materials and methodsIn this interventional study on patients with ischemic heart disease (IHD) referred to the Cardiac Rehabilitation Center of Chamran Hospital, Isfahan, Iran. One-hundred and twelve patients were randomly divided into two groups of 12 and 24 sessions of CR [mean age: 59.2 ± (9.02) and 60.7 ± (9.3) years, respectively] and underwent a CR program. All information was collected in two stages, before the beginning of the program and after completion of 12- and 24-session rehabilitation programs. The data collection tools were demographics questionnaire, the International Physical Activity Questionnaires (IPAQ), McNew Quality of Life Questionnaire, Beck Depression Inventory (BDI), and Zung Self-Rating Anxiety Scale (SAS).ResultsThe results of this study showed that in both groups, total physical activity (PA) and functional capacity increased, and the quality of life (QOL) was statistically improved. Comparison of changes in mean differences at the end of the rehabilitation periods between the two groups, showed that only the weight, body mass index (BMI), waist circumference (WC) and high-density lipoprotein (HDL) in the 24-session group significantly decreased compared to the 12-session group and, but no significant difference in other variables was observed.ConclusionOverall, the findings of this study support the overall benefits of the CR program in both the short and the long term. Therefore it can be suggested that a short-term program can still be a valuable option for reducing the risk in cardiac patients and meeting their service needs.

The New European Questionnaire for Assessment of Quality of Life of Patients With Ischemic Heart Disease: HeartQoL

Kardiologiia ◽  
2016 ◽  
Vol 8_2016 ◽  
pp. 66-72 ◽  
Author(s):  
N.V. Pogosova Pogosova ◽  
I.H. Boycharov Boycharov ◽  
O.Yu. Sokolova Sokolova ◽  
V.A. Vygodin Vygodin ◽  
◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Ischemic Heart

Abstract 241: Evaluation of the Parameters of the Euro Qol- 5 D Questionnaire Among Patients With Ischemic Heart Disease With Normal and Elevated BMI

2015 ◽  
Vol 8 (suppl_2) ◽  
Author(s):  
Cyril James ◽  
Shreya Ohri ◽  
Snezhana Tisheva ◽  
Dilyana Yakova ◽  
Martin Hristov ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Self Care ◽  
Ischemic Heart ◽  
Usual Activity ◽  
Female Ratio ◽  
Coronary Syndrome ◽  
The Impact

Objective: The epidemic of obesity and obesity related morbidities is an important public health challenge, and is paralleled by growing incidence of metabolic syndrome which acts as a strong and significant risk factor for Ischemic heart disease and other atherosclerotic vascular events. The psychological impact of these chronic conditions can be very disturbing. In practical terms the functional effect of an illness and its therapy upon a patient, as perceived by the patient - could be estimated by introducing the quantitative approach of - Health Related Quality of Life (HRQoL). Aim: The aim of this study is to evaluate the impact of obesity on quality of life of patients with ischemic heart disease. Design and method: Questionnaire based cross sectional study was conducted among patients with established Coronary Artery Disease admitted in the Department of Cardiology in the University Hospital. 520 patients who were admitted in the Cardiology Department between 1st of January 2012 and 30th June 2014 with acute coronary syndrome or coronary angiographic or Electrocardiography evidence of ischemic heart disease were included in the study, stratified by age, sex and BMI ( normal weight 18.5 - 24.9, overweight 25 - 29.9, obese 30 and above). EuroQol - 5D (EQ-5D) was administered in the patients during their hospital stay. EQ-5D comprises 5 dimensions: mobility, self-care, usual activities, pain/discomfort and anxiety/depression. Each dimension has 5 levels: no problems, slight problems, moderate problems, severe problems and extreme problems. The height, weight and basic laboratory parameters were recorded. Results: Mean age of the participants was 65.1± 10.6 years. Male female ratio was 0.76. The distribution of patients in BMI groups was 36.8%/ 24.4%/ 38.8%. Statistically significant differences between BMI groups were seen in Usual activity (p=0.005) and self-care (p=0.044) dimensions of EQ-5D-5L with poorest outcome in the obese. We have found significantly positive correlation between BMI and usual activities (R=0.234, p=0.001) and between age and anxiety (R= 0.366 p=0.045). Mean BMI of patients with extreme problems with extreme problems with usual activities is significantly greater than those with lower intensity of problems. Patients with extreme anxiety tend to have higher mean age. Conclusion: Our study revealed that Ischemic heart disease patients with obesity had impaired QoL in terms of health, mobility, usual activity, discomfort and anxiety. Hence non-obese ischemic heart disease patients had a better sense of overall wellbeing.

Sign in / Sign up

Export Citation Format

Share Document