scholarly journals Auditory evoked potential P300 characteristics in adults with and without idiopathic bilateral tinnitus

2020 ◽  
Author(s):  
Sirvan Najafi ◽  
Masoumeh Rouzbahani
Keyword(s):  
Cognitive Processes ◽  
Evoked Potential ◽  
Auditory Evoked Potential ◽  
P300 Amplitude ◽  
Oddball Paradigm ◽  
Pitch Matching ◽  
Eye Blink ◽  
Keywords Tinnitus ◽  
Auditory P300 ◽  
Attention Disorder

Background and Aim: Based on neurophysio­logical measurements, auditory and non-audi­tory pathways are involved in tinnitus. People who experience tinnitus may suffer from several problems such as attention disorder. The audi­tory evoked potential P300 is an endogenous response and depends on cognitive processes like attention. The purpose of this study was to compare the auditory P300 characteristics (amp­litude and latency) in adults with and without tinnitus. Methods: Participants were 20 adults with idio­pathic bilateral tinnitus with mean duration of 8.4 ± 4.73 months, and 20 healthy adults. The P300 was recorded using oddball paradigm con­sisted of two standard (1000 Hz) and target sti­muli (2000 Hz). To reduce eye blink during recording, all participants was instructed to look at and fixate on a dot sign located in front of them. The tinnitus handicap inventory (THI) was completed and pitch matching (PM) and loudness matching (LM) were measured in tinn­itus group. Results: P300 amplitude was lower at both Fz and Cz electrode placements in tinnitus patients compared to the normal group, but it was not statistically significant (p = 0.57). Tinnitus pati­ents had delayed latency at Fz and Cz, but this difference was not significant either psychomet­ric and psychoacoustic assessment had no statis­tically significant correlation with P300 ampli­tude and latency. Conclusion: It seems that P300 characteristics are not different between adults with and with­out idiopathic bilateral tinnitus, may be due to using low sample size. Keywords: Tinnitus; auditory evoked potential P300; attention

scholarly journals Analysis of the influence of bromazepam on cognitive performance through the visual evoked potential (P300)

2005 ◽  
Vol 63 (2a) ◽  
pp. 228-234 ◽  
Author(s):  
Fernanda Puga ◽  
Heloisa Veiga ◽  
Maurício Cagy ◽  
Kaleb McDowell ◽  
Roberto Piedade ◽  
...  
Keyword(s):  
Cognitive Processes ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Digit Span ◽  
Event Related Potentials ◽  
Oddball Paradigm ◽  
Behavioral Measures ◽  
Experimental Conditions ◽  
Double Blind ◽  
Related Potentials

Benzodiazepines have been used in the pharmacological treatment of anxiety for over four decades. However, very few studies have combined bromazepam and event-related potentials (ERP). The present study aimed at investigating the modulatory effects of this drug on brain dynamics. Specifically, the effects of bromazepam (3mg) on the P300 component of the ERP were tested in a double-blind experiment. The sample, consisting of 15 healthy subjects (7 male and 8 female), was submitted to a visual discrimination task, which employed the "oddball" paradigm. Electrophysiological (P300) and behavioral measures (stroop, digit span, and reaction time) were analyzed across three experimental conditions: placebo 1, placebo 2, and bromazepam. Results suggest that the effects of bromazepam (3mg) on cognitive processes are not apparent. In spite of what seems irrefutable in current literature, bromazepam did not produce evident effects on the behavioral and electrophysiological variables analyzed.

scholarly journals Spatial Distribution of the N2 and P300 Components of the Auditory Evoked Potential in Women with Arterial Hypertension: A study in the Russian Arctic

2021 ◽  
Vol 11 (3) ◽  
pp. 281-285
Author(s):  
Olga V. Krivonogova ◽  
Elena V. Krivonogova ◽  
Liliya V. Poskotinova
Keyword(s):  
Spatial Distribution ◽  
Auditory Evoked Potential ◽  
P300 Amplitude ◽  
Oddball Paradigm ◽  
Russian Arctic ◽  
Working Age ◽  
P3 Amplitude ◽  
Group 2 ◽  
The Right ◽  
Group 1

The aim of this study was to evaluate the spatial distribution of the latencies and amplitudes of the N2 and P3 (or P300) components of the AEP in the Russian Arctic working-age women with different levels of BP. Methods and Results: A total of 25 working-age women living in Nadym city for more than 20 years took part in this study. Group 1 (n=12, control group) consisted of women with BP within the normal range (<130/90 mmHg); Group 2 (n=13) consisted of women with AH (AH duration from 1 to 10 years). The parameters of the N2 and P300) components of the AEP were evaluated using an electroencephalograph (Neuron-Spectrum-4/VPM, Russia). An auditory oddball paradigm was used to elicit the oddball ERPs. In Group 2, compared with Group 1, the N2 latency was more pronounced in the parietal (P4, P3), central (C4, C3), frontal (F4, F3), and left temporal (T3, F7) regions. The N2 amplitude in all studied brain regions in individuals of both groups was comparable. The P300 latency did not differ between the two groups. In Group 2, the P300 amplitude was significantly lower in the parietal region (P3) on the left, and in the central and temporal regions on the right (C4, T4). In Group 2, inverse correlations between DBP and the P3 amplitude were revealed in the central (C4: r=-0.88, P=0.001; C3: r=-0.86, P=0.001), frontal (F4: r=-0.76; P=0.01; F3: r=-0.93, P=0.001), and anterior-temporal cerebral regions (F8: r=-0.65, P=0.04; F7: r=-0.64, P=0.04). SBP correlated with the P3 amplitude in the right mid-temporal region (T4: r=0.64, P=0.04). Conclusion: The features of the spatial distribution of the N2 and P3 components of the AEP can be used for early diagnosis of the risk of developing cognitive disorders in AH patients.

scholarly journals THE CORRELATION BETWEEN INDIVIDUAL MINUTE DATA AND THE Р300 AUDITORY EVOKED POTENTIAL IN YOUNG PEOPLE WITH DIFFERENT LEVELS OF INTERNET ADDICTION BEHAVIOR

2020 ◽  
Vol 13 (3) ◽  
pp. 93-101
Author(s):  
Olga Vyacheslavovna Krivonogova ◽  
Elena Vyacheslavovna Krivonogova ◽  
Liliya Vladimirovna Poskotinova
Keyword(s):  
Decision Making ◽  
Young People ◽  
Internet Addiction ◽  
Evoked Potential ◽  
Auditory Evoked Potential ◽  
P300 Amplitude ◽  
Minimal Risk ◽  
Individual Minute ◽  
Different Levels

Background. The nature of changes in cerebral biopotentials as a neurobiological foundation of individual time in persons with different levels of internet addiction behavior remains insufficiently studied. However, these biopotentials reflect decision making speed and the quality of significant stimulus detection by brain structures. The paper aims to establish the correlation between the P300 cognitive evoked potential and individual minute (IM) test in young people with different levels of Internet addiction (IA) risk. Materials and methods. Healthy young people aged 16-17 years (n = 51) participated in the study. The survey was conducted according to the Chen scale (CIAS – Chen Internet Addiction Scale) modified by V. Malygin. This modification implies the calculation of the CIAS total score and the subjective assessment of time intervals by the IM test. The amplitude and latency of the P 300 auditory evoked potential were determined using the Neuron-Spectrum - 4 /VMP electroencephalograph (Neurosoft, Russia) in the frontal (F3, F4), temporal (F7, F8, T3, T4), central (C3, C4) and parietal (P3, P4) leads of the electroencephalogram. Results. No significant correlations were found between the IM time, P 300 data and the severity of IA signs in young people with a minimal risk of IA (less than 43 scores by CIAS). There was a decrease in the IM time and an increase in P300 amplitude (mainly in the frontal and anterior temporal areas) in persons with a risk of IA (43–65 scores by CIAS). In persons with a stable IA pattern (more than 65 scores by CIAS), the minimum P 300 amplitude in the F7, F8 brain areas was found against a relative increase in the IM time and the number of errors in decision making. Conclusion. An increased risk of Internet addiction behavior in young people is accompanied by phase changes in the ratios of P 300 amplitude (mainly in the anterior temporal areas), the quality of information processing and individual time perception.

P300 Amplitude and Topography in an Autobiographical Oddball Paradigm Involving Simulated Amnesia

2002 ◽  
Vol 16 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Antoinette R. Miller ◽  
J. Peter Rosenfeld ◽  
Matthew Soskins ◽  
Marianne Jhee
Keyword(s):  
Task Difficulty ◽  
Event Related Potential ◽  
P300 Amplitude ◽  
Oddball Paradigm ◽  
Amplitude Difference ◽  
P300 Component ◽  
Oddball Task

Abstract The P300 component of the event-related potential was recorded during two blocks of an autobiographical oddball task. All participants performed honestly during the first block (Phone), i.e., the oddball stimuli were phone numbers. During the second block (Birthday), in which the oddball stimuli were participants' birthdays, a Truth group (N = 13) performed honestly and a Malinger group (N = 14) simulated amnesia. Amnesia simulation significantly reduced P300 amplitudes, both between groups and within the Malinger group (Phone vs. Birthday), possibly because of an increase in task difficulty in the Malinger condition. Analysis of scaled amplitudes also indicated a trend for a feigning-related alteration in P300 topography. Bootstrapping of peak-to-peak amplitudes detected significantly more (93%) Malinger individuals than bootstrapping of baseline-to-peak amplitudes (64%). Bootstrapping also provided evidence of a feigning-related amplitude difference between oddball stimuli (i.e., Phone > Birthday) in 71% of Malinger group individuals. In this comparison, the peak-to-peak measure also performed significantly better in intraindividual diagnostics.

Electrophysiologic Correlates of Attention versus Distraction in Young and Elderly Listeners

2002 ◽  
Vol 13 (07) ◽  
pp. 383-391 ◽  
Author(s):  
Albert R. De Chicchis ◽  
Michael Carpenter ◽  
Jerry L. Cranford ◽  
Murvin R. Hymel
Keyword(s):  
Selective Attention ◽  
Evoked Potential ◽  
The Elderly ◽  
Auditory Evoked Potential ◽  
Competition Effect ◽  
Specific Target ◽  
Attention Effect ◽  
Competition Effects ◽  
Significant Attention ◽  
Versus Stimulus

This study examined the effects of selective attention versus stimulus competition on the late auditory evoked potential (LAEP) in 20 young and 20 elderly listeners. In a series of test runs, different oddball tonal sequences were presented to one or both ears, and listeners were instructed to attend to tones at a specific target ear. Peak amplitudes were recorded for the N1, P2, and the early and late N2 components of the LAEP. Significant attention effects were found for all four components. N1 amplitudes increased significantly when participants attended to the target stimuli, whereas the amplitudes of P2, N2e, and N2l decreased. For all LAEP components except N2l, the attention effect did not differ between young and elderly listeners. Significant competition effects also were found for all four components. Amplitudes were significantly larger in monaural than binaural conditions for all components except N2l. The magnitude of this competition effect also was significantly larger for the young listeners than the elderly for all components except N1. These results suggest that the ability to attend selectively to sounds may be more resistant to normal aging than are effects related to stimulus competition.

scholarly journals The effect of early versus late lipid infusion in parenteral nutrition on the biochemical and cortical auditory evoked potential parameters in preterm neonates

2019 ◽  
Vol 67 (1) ◽  
Author(s):  
Rania Mohamed Abdou ◽  
Hoda Mahmoud Ibrahim Weheiba
Keyword(s):  
Weight Gain ◽  
Parenteral Nutrition ◽  
Biochemical Parameters ◽  
Evoked Potential ◽  
Demographic Data ◽  
Auditory Evoked Potential ◽  
Preterm Neonates ◽  
Lipid Infusion ◽  
Significant Difference ◽  
Cortical Auditory Evoked Potential

Abstract Background As brain activity depends greatly on the functions provided by lipid membranes, dietary fat in early life can affect the developing nervous system. Despite the adoption of an early more aggressive parenteral nutrition approach with amino acid infusions still reluctance to the early use of intravenous lipids in neonates. Aim To compare the effect of delayed versus early introduction of intravenous lipid in preterm on the biochemical parameters and on brain development by the cortical auditory evoked potential (CAEP) latency and amplitude. Methods This is a comparative study included 49 neonates admitted at the ain shams university NICUs. Participants were divided into two groups: 26 in group of early lipid infusion and 23 in late lipid infusion, Demographic data, and biochemical parameters were documented during the 1st 2 weeks of life. The CAEP was performed at age of 6 months. The latency and amplitude of P1 were recorded and compared between both groups. Results In the present work we found that group of early lipid infusion had reach their full oral intake earlier with shorter duration of parenteral nutrition and length of stay. They had better weight gain and significantly better glucose level control than group of late lipid infusion. There was no significant difference in the other chemical parameters between both groups expect for the higher incidence of cholestasis in the group of late lipid infusion. At 6 months of age, the group of early lipid infusion had significantly shorter latency and amplitude of P1 than the group of late lipid infusion. Conclusion Early effective nutrition positively affect feeding tolerance and weight gain and maturation of higher brain centers brain.

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