scholarly journals 64Cu-PSMA-617: A novel PSMA-targeted radio-tracer for PET imaging in gastric adenocarcinoma xenografted mice model

Oncotarget ◽  
2017 ◽  
Vol 8 (43) ◽  
pp. 74159-74169 ◽  
Author(s):  
Xue-Di Han ◽  
Chen Liu ◽  
Fei Liu ◽  
Qing-Hua Xie ◽  
Te-Li Liu ◽  
...  
Keyword(s):  
Gastric Adenocarcinoma ◽  
Pet Imaging ◽  
Mice Model ◽  
Radio Tracer

Stereotactic comparison study of 18F-Alfatide and 18F-FDG PET imaging in LLC tumor-bearing C57BL/6 mice model.

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e20070-e20070
Author(s):  
Yuchun Wei ◽  
Yongsheng Gao ◽  
Jianbo Zhang ◽  
Xudong Hu ◽  
Wenhong Hou ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Fdg Pet ◽  
Comparison Study ◽  
Mice Model ◽  
Tumor Bearing ◽  
18F Fdg

WE-D-L100J-01: In Vivo PET Imaging of Angiogenesis in Tumor Mice Model with 64Cu Labeled Avastin

2007 ◽  
Vol 34 (6Part20) ◽  
pp. 2596-2596
Author(s):  
T Chang ◽  
Z Wang
Keyword(s):  
Pet Imaging ◽  
Mice Model

scholarly journals Comparison of a New 68Ga-Radiolabelled PET Imaging Agent sCD146 and RGD Peptide for In Vivo Evaluation of Angiogenesis in Mouse Model of Myocardial Infarction

Cells ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 2305
Author(s):  
Anaïs Moyon ◽  
Philippe Garrigue ◽  
Samantha Fernandez ◽  
Fabien Hubert ◽  
Laure Balasse ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Functional Recovery ◽  
Pet Imaging ◽  
Vascular Diseases ◽  
Αvβ3 Integrin ◽  
Mice Model ◽  
In Vivo Evaluation ◽  
Tissue Fibrosis ◽  
18F Fdg

Ischemic vascular diseases are associated with elevated tissue expression of angiomotin (AMOT), a promising molecular target for PET imaging. On that basis, we developed an AMOT-targeting radiotracer, 68Ga-sCD146 and performed the first in vivo evaluation on a myocardial infarction mice model and then, compared AMOT expression and αvβ3-integrin expression with 68Ga-sCD146 and 68Ga-RGD2 imaging. After myocardial infarction (MI) induced by permanent ligation of the left anterior descending coronary artery, myocardial perfusion was evaluated by Doppler ultrasound and by 18F-FDG PET imaging. 68Ga-sCD146 and 68Ga-RGD2 PET imaging were performed. In myocardial infarction model, heart-to-muscle ratio of 68Ga-sCD146 imaging showed a significantly higher radiotracer uptake in the infarcted area of MI animals than in sham (* p = 0.04). Interestingly, we also observed significant correlations between 68Ga-sCD146 imaging and delayed residual perfusion assessed by 18F-FDG (* p = 0.04), with lowest tissue fibrosis assessed by histological staining (* p = 0.04) and with functional recovery assessed by ultrasound imaging (** p = 0.01). 68Ga-sCD146 demonstrated an increase in AMOT expression after MI. Altogether, significant correlations of early post-ischemic 68Ga-sCD146 uptake with late heart perfusion, lower tissue fibrosis and better functional recovery, make 68Ga-sCD146 a promising radiotracer for tissue angiogenesis assessment after MI.

Alterations in regional decreased cerebral blood flow in patients with irritable bowel syndrome-A PET imaging study

2001 ◽  
Vol 120 (5) ◽  
pp. A637-A637
Author(s):  
Y RINGEL ◽  
D DROSSMAN ◽  
T TURKINGTON ◽  
B BRADSHAW ◽  
R COLEMAN ◽  
...  
Keyword(s):  
Blood Flow ◽  
Irritable Bowel Syndrome ◽  
Cerebral Blood Flow ◽  
Pet Imaging ◽  
Imaging Study ◽  
Irritable Bowel
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