Clinical Evaluation of a Biodegradable Collagen Membrane in Guided Tissue Regeneration

ABSTRACT Aim To report a well succeeded use of cyanoacrylate adhesive for fixating a resorbable membrane during a guided tissue regeneration procedure (GTR). Background The immobilization of membranes in GTR is essential for establishing proper environment for cell differentiation and tissue regeneration. However, some membranes are very difficult to be kept in position by sutures and its fixation by mini screws or pins may be time consuming and expensive. Case description A 47-year-old woman presenting a vertical bone defect at the palatal aspect of the left central incisor was treated by GTR using particulate autogenous bone graft associated to a collagen membrane. The membrane was glued to the bone surrounding the defect and to the tooth surface with cyanoacrylate adhesive. The postoperative period was uneventful and 4 years later, excellent results in terms of radiographic filling of the defect and reduction of the probing depth were seen. For illustrative purposes, histological findings obtained during a previous experiment in calvaria of guinea pigs is shown, characterizing a foreign body granuloma and proving that the cyanoacrylate adhesive is a safe tool in GTR. Conclusion The use of a membrane glued with cyanoacrylate to immobilize membranes in GTR is viable and safe from both technical and biological standpoints and may be advantageous for clinical and research purposes. Clinical significance The alternative method for membrane fixation shown in this case report can contribute to simplify the technique in GTR procedures. How to cite this article de Rezende MLR, de Oliveira Cunha P, Damante CA, Santana ACP, Greghi SLA, Zangrando MSR. Cyanoacrylate Adhesive as an Alternative Tool for Membrane Fixation in Guided Tissue Regeneration. J Contemp Dent Pract 2015;16(6):512-518.

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A Comparative Evaluation of the Effectiveness of Guided Tissue Regeneration by Using a Collagen Membrane with or without Decalcified Freeze-Dried Bone Allograft in the Treatment of Infrabony Defects : A Clinical and Radiographic Study

Smile Dental Journal ◽

10.12816/0001910 ◽

2013 ◽

Vol 8 (3) ◽

pp. 40-40

Author(s):

V. K. Kher ◽

M. L. Bhongade ◽

A. P. Kolte

Keyword(s):

Tissue Regeneration ◽

Comparative Evaluation ◽

Bone Allograft ◽

Guided Tissue Regeneration ◽

Collagen Membrane ◽

Radiographic Study ◽

Freeze Dried ◽

Infrabony Defects

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Guided Tissue Regeneration (GTR) Using Collagen Membrane with Polylactic Acid Frame (PLA): Case Report

Acta Scientific Dental Scienecs ◽

10.31080/asds.2021.05.1162 ◽

2021 ◽

Vol 5 (8) ◽

pp. 03-08

Author(s):

Donizete Heliano Oliveira Borges ◽

Talita Soares ◽

Lucas Alves Ferreira ◽

Francisco Jose Corrêa Braga ◽

Felipe Andres Ortiz Poblete ◽

...

Keyword(s):

Case Report ◽

Polylactic Acid ◽

Tissue Regeneration ◽

Guided Tissue Regeneration ◽

Collagen Membrane

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Evaluation of a bioabsorbable collagen membrane in the treatment of localized gingival recession – a case series”

RGUHS Journal of Dental Sciences ◽

10.26715/rjds.9_2_10 ◽

2017 ◽

Vol 9 (2) ◽

pp. 37-43

Author(s):

Harsha. M B

Keyword(s):

Tissue Regeneration ◽

Case Series ◽

Gingival Recession ◽

Class Ii ◽

Guided Tissue Regeneration ◽

Class I ◽

Collagen Membrane ◽

Root Caries ◽

Root Coverage ◽

Coronally Advanced Flap

BACKGROUND: Gingival recession (GR), often an aesthetic concern to the patient, is also associated with root sensitivity, and has a predilection to root caries. The purpose of this case series was to evaluate a bioabsorbable collagen membrane for root coverage with guided tissue regeneration (GTR) procedure, in localized gingival recession defects. METHODS: Three cases presented in this case series, showing a localized Miller’s Class I or Class II gingival recession were treated for root coveragewith GTR-based collagen membrane. The graft was completely covered with coronally advanced flap and followed up to 6th month postoperatively. RESULTS: Six months following the procedure, the root coverage was found to be 100% in all three cases. The root coverage obtained appeared structurally and functionally stable. CONCLUSION: It may be concluded that the resorbable collagen membrane could be reliably used in the treatment of gingival recession.

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The Application of Three-Dimensional Printing Model and Platelet-Rich Fibrin Technology in Guided Tissue Regeneration Surgery for Severe Bone Defects

Journal of Oral Implantology ◽

10.1563/aaid-joi-d-17-00231 ◽

2019 ◽

Vol 45 (1) ◽

pp. 35-43 ◽

Cited By ~ 7

Author(s):

Lihong Lei ◽

Yuanyuan Yu ◽

Ting Ke ◽

Weilian Sun ◽

Lili Chen

Keyword(s):

Tissue Regeneration ◽

Alveolar Bone ◽

Three Dimensional ◽

Guided Tissue Regeneration ◽

Collagen Membrane ◽

Three Dimensional Printing ◽

Platelet Rich Fibrin ◽

Bony Anatomy ◽

Regenerative Periodontal Therapy ◽

Radiographic Followup

A 36-year-old male patient diagnosed with severe chronic periodontitis was treated with novel surgery for his maxillary right lateral incisor. Preoperatively, a 3D printer was used, based on CBCT datasets, to produce a photosensitive resin bony anatomy replica. The patient's blood was centrifuged to obtain advanced platelet-rich fibrin (A-PRF) and injected platelet-rich fibrin (I-PRF), then mixed with Bio-Oss and packed onto the 3D replica to form the ideal shape. The replica was positioned at the planned sites without changes. The A-PRF membrane was applied over the replica as well as a Bio-Gide collagen membrane. Fifteen months after the surgery, clinical and radiographic followup revealed greatly reduced pocket depths and significant 3D alveolar bone fill at the treatment site. Based on these short-term results, the initial 3D printing surgical temple assisted guided tissue regeneration method resulted in significant clinical and radiographic improvements; A-PRF/I-PRF should be considered an ideal biomaterial for regenerative periodontal therapy.

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