scholarly journals Safety and feasibility of single-incision radical vulvectomy: a novel approach for the treatment of vulvar cancer

2021 ◽  
Vol 9 (4) ◽  
pp. 320-320
Author(s):  
Liqing He ◽  
Gaowen Chen ◽  
Xiaoxuan Li ◽  
Youhong Zheng ◽  
Mengting Wu ◽  
...  
2020 ◽  
Vol 38 (8-9) ◽  
pp. 531-534
Author(s):  
Vittorio Quercia ◽  
Gabriele Saccone ◽  
Antonio Raffone ◽  
Antonio Travaglino ◽  
Mariano Favale ◽  
...  

Pancreatology ◽  
2018 ◽  
Vol 18 (4) ◽  
pp. S170
Author(s):  
Rebecca Saunders ◽  
Jonathan Evans ◽  
Rebekah McCready ◽  
Faye Hughes ◽  
Michael Raraty ◽  
...  

2021 ◽  
Vol 11 ◽  
Author(s):  
Yuhan Wang ◽  
Rongchun Lin ◽  
Bingzhong Zhang ◽  
Hui Zhou ◽  
Zhongqiu Lin ◽  
...  

BackgroundVulvar cancer is the fourth most common gynecologic cancer, and prognosis is poor in advanced vulvar cancer patients. Treatment for advanced vulvar cancer has not been satisfactory. In this report, we firstly report a FIGO IVB vulva verrucous carcinoma patient who obtained good prognosis after systemic treatment.Case PresentationA patient was admitted to hospital due to her vulvar lesion persistent for past 14 years. The vulvar mass has widely invaded urethra, part of anus, the lower third of the vagina, bilateral superior and inferior branches of pubis, and bilateral internal and external muscles of obturator. Multiple metastatic lymph nodes were also found in the pelvic cavity. The histopathological studies confirmed vulvar verrucous carcinoma with a PD-L1 overexpression. After six courses of neoadjuvant chemotherapy and pembrolizumab, the patient underwent radical vulvectomy and achieved optimal cytoreduction. Postoperative pathology found no residual tumor. The patient then received one course of postoperative chemotherapy and pembrolizumab, underwent radiation therapy, and was disease free after 6 months follow-up.ConclusionOur individualized treatment strategy is successful. Pembrolizumab is safe and effective in the treatment of advanced vulvar verrucous carcinoma with PD-L1 overexpression.


2007 ◽  
Vol 17 (1) ◽  
pp. 294-297 ◽  
Author(s):  
Y De Mooij ◽  
M. P.M. Burger ◽  
M. S. Schilthuis ◽  
M. Buist ◽  
J. Van Der Velden

Partial resection of the urethra is sometimes necessary in the surgical treatment of locally advanced vulvar cancer. In this study, the frequency of urinary incontinence after partial urethral resection was compared with that of patients who were treated without partial resection of the urethra. Eighteen patients with vulvar cancer encroaching or infiltrating the urethra, treated by a radical vulvectomy and partial urethrectomy, were compared with 17 patients treated by vulvectomy without partial removal of the urethra. Data on urinary incontinence pre- and postoperatively from both groups were retrospectively collected from the patient files. A questionnaire on urinary incontinence was sent to a subset of patients from both groups in order to get information on the current micturation pattern. In four out of 18 patients (22%) with a partial urethrectomy, incontinence was reported, versus two out of 17 patients (12%) in the control group (P= 0.860). Eight patients in the study group and 12 in the control group are currently alive, and all responded to the questionnaire. Two (25%) in the study group and three (25%) in the control group reported to have current symptoms of urinary incontinence. This retrospective study shows that partial resection of 1–1.5 cm of the distal urethra in addition to a radical local excision for vulvar cancer does not result in a significant increase in the frequency of urinary incontinence, compared with vulvar cancer patients without partial urethrectomy.


2011 ◽  
Vol 15 (1) ◽  
pp. 61-65 ◽  
Author(s):  
M. Ragupathi ◽  
D. I. Ramos-Valadez ◽  
M. D. Yaakovian ◽  
E. M. Haas

2016 ◽  
Author(s):  
Reena Rani ◽  
Asmita Rathore ◽  
Latika Sahu ◽  
Sangeeta Bhasin

Vulvar melanoma is a rare type of gynaecological malignancy. Its poor prognosis and aggressive course provides it more significance than any other vulvar cancer. The knowledge about vulvar melanoma tends to be relatively low as compared to that of squamous cell carcinoma of vulva. This lack of data is due to the infrequency with which vulvar melanoma occurs in any place. In this presentation we are reporting a rare case of vulvar melanoma in a 70 year old lady diagnosed after complaint of persistent vulvar itching discharge per vaginum and a growth on labia on examination. She underwent radical vulvectomy with bilateral inguinofemoral lymphadenectomy and radiotherapy in postoperative period.


2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Samer Al Sawalhi ◽  
Deping Zhao ◽  
Haomin Cai ◽  
Yuxing Jin

Subcostal access is a novel approach for anatomical lung resection. To perform surgery via this access, specially designed long instruments are required. Subcostal access provides excellent visualization of the mediastinum and anterior lung hilum. We exhibit here a subcostal middle lobectomy with systematic en-block mediastinal lymphadenectomy in an obese 52-year-old male patient with body mass index (BMI=37.7) performed via this single incision. The operation was completed efficiently within 30 minutes with negligible postoperative pain.


2016 ◽  
Author(s):  
Reena Rani ◽  
Asmita Rathore ◽  
Latika Sahu ◽  
Sangeeta Bhasin

Vulvar melanoma is a rare type of gynaecological malignancy. Its poor prognosis and aggressive course provides it more significance than any other vulvar cancer. The knowledge about vulvar melanoma tends to be relatively low as compared to that of squamous cell carcinoma of vulva. This lack of data is due to the infrequency with which vulvar melanoma occurs in any place. In this presentation we are reporting a rare case of vulvar melanoma in a 70 year old lady diagnosed after complaint of persistent vulvar itching discharge per vaginum and a growth on labia on examination. She underwent radical vulvectomy with bilateral inguinofemoral lymphadenectomy and radiotherapy in postoperative period.


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