scholarly journals Antibacterial and antifungal activity of intraoral products containing phthalocyanine: in vitro study

2021 ◽  
Author(s):  
Bernardo da Fonseca Orcina ◽  
Verônica Caroline Brito Reia ◽  
Caique Andrade Santos ◽  
Milena Helen Peres ◽  
Fabiano Vieira Vilhena ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Contact Time ◽  
In Vitro Study ◽  
Ventilator Associated Pneumonia ◽  
Antibacterial And Antifungal Activity ◽  
Good Laboratory ◽  
Bacteria And Fungi ◽  
Antibacterial And Antifungal ◽  
Suspension Test

Abstract The present study aimed to evaluate the in vitro antiseptic efficacy of a mouthwash and a dental gel containing phthalocyanine derivatives (Pc) against bacteria and fungi frequently found in patients with ventilator-associated pneumonia. The experiment in this study was conducted following Good Laboratory Practices. The product was tested at concentrations of 0.015% (mouthwash) and 0.100% (dental gel). The contact time of the suspension test (Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella sp., Candida albicans, and Aspergillus niger) was 60 s (1 min). In this analysis, the Phtalox® Mouthwash and Dental Gel resulted in a 99.99% reduction against the tested microorganisms after 1 min of contact time in both products. The Pc-containing mouthwash and dental gel were effective against bacteria and fungi found in patients with ventilator-associated pneumonia.

Substituted 4-Formyl-2H-chromen-2-ones: Their Reaction with N-(2,3,4,6-Tetra-Oacetyl- β-D-galactopyranosyl)thiosemicarbazide, Antibacterial and Antifungal Activity of Their Thiosemicarbazone Products

2020 ◽  
Vol 24 (19) ◽  
pp. 2272-2282
Author(s):  
Vu Ngoc Toan ◽  
Nguyen Minh Tri ◽  
Nguyen Dinh Thanh
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Candida Albicans ◽  
Selenium Dioxide ◽  
Antibacterial And Antifungal Activity ◽  
E Coli ◽  
Antibacterial And Antifungal Activities ◽  
Alkyl Ethers ◽  
Antibacterial And Antifungal

Several 6- and 7-alkoxy-2-oxo-2H-chromene-4-carbaldehydes were prepared from corresponding alkyl ethers of 6- and 7-hydroxy-4-methyl-2-oxo-2H-chromen-2-ones by oxidation using selenium dioxide. 6- and 7-Alkoxy-4-methyl-2H-chromenes were obtained with yields of 57-85%. Corresponding 4-carbaldehyde derivatives were prepared with yields of 41-67%. Thiosemicarbazones of these aldehydes with D-galactose moiety were synthesized by reaction of these aldehydes with N-(2,3,4,6-tetra-O-acetyl-β-Dgalactopyranosyl) thiosemicarbazide with yields of 62-74%. These thiosemicarbazones were screened for their antibacterial and antifungal activities in vitro against bacteria, such as Staphylococcus aureus, Escherichia coli, and fungi, such as Aspergillus niger, Candida albicans. Several compounds exhibited strong inhibitory activity with MIC values of 0.78- 1.56 μM, including 8a (against S. aureus, E. coli, and C. albicans), 8d (against E. coli and A. niger), 9a (against S. aureus), and 9c (against S. aureus and C. albicans).

Microwave Mediated Michaelis-Arbuzov Reaction to Synthesize Bioactive Phenylphosphonate Derivatives Under Solvent Free Condition

2019 ◽  
Vol 4 (1) ◽  
pp. 1-6
Author(s):  
B. Sujatha ◽  
Ch. Subramanyam ◽  
K. Prasada Rao
Keyword(s):  
Solvent Free ◽  
Arbuzov Reaction ◽  
Antibacterial And Antifungal Activity ◽  
Environment Friendly ◽  
Free Condition ◽  
Microwave Assisted ◽  
Solvent Free Condition ◽  
Bacteria And Fungi ◽  
Antibacterial And Antifungal

Microwave assisted easy, efficient, and environment friendly process has been devised for the synthesis of phosphonates within minutes via microwave-assisted Michaelis-Arbuzov reaction. The desired products were obtained in excellent yields and in high purity under solvent-free and catalyst-free conditions. The structure of all the synthesized compounds was confirmed by spectral and CHN analysis. in vitro Antibacterial and antifungal activity of these compounds was also analyzed. Majority of the title compounds showed good inhibition towards bacteria and fungi.

scholarly journals Antimicrobial activity of Hypericum annulatum moris and Hypericum elegans stephan ex willd. essential oils from Serbia

2013 ◽  
Vol 19 (1) ◽  
pp. 7-11
Author(s):  
Aleksandra Djordjevic ◽  
Jelena Lazarevic ◽  
Violeta Mitic ◽  
Radosav Palic ◽  
Gordana Stojanovic
Keyword(s):  
Antimicrobial Activity ◽  
Antifungal Activity ◽  
Essential Oil ◽  
Essential Oils ◽  
Antibacterial And Antifungal Activity ◽  
Significant Difference ◽  
Bacteria And Fungi ◽  
Antibacterial And Antifungal ◽  
Hypericum Species

The in vitro antimicrobial activity of Hypericum annulatum and Hypericum elegans essential oils was evaluated against a panel of standardized bacteria and fungi using broth microdilution assay. Both essential oils showed antimicrobial activity against all the tested microorganisms. Hypericum annulatum essential oil showed better antibacterial than antifungal activity, being more effective against Pseudomonas aeruginosa and Escherichia coli while H. elegans essential oil showed no significant difference between antibacterial and antifungal activity. Antimicrobial testing of ?-pinene, ?-pinene and ?-myrcene compounds was also performed. All the compounds were active against all the tested microorganisms, however, based on the MIC, MBC and MFC values, none of these compounds could be thought of as the main bearer of the oils? antimicrobial activity. This is the first report regarding the antimicrobial activity of the essential oils of the two Hypericum species.

scholarly journals Chemical constituents, in vitro antibacterial and antifungal activity of Mentha×Piperita L. (peppermint) essential oils

2019 ◽  
Vol 31 (4) ◽  
pp. 528-533 ◽  
Author(s):  
Nagarjuna Reddy Desam ◽  
Abdul Jabbar Al-Rajab ◽  
Mukul Sharma ◽  
Mary Moses Mylabathula ◽  
Ramachandra Reddy Gowkanapalli ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Essential Oils ◽  
Chemical Constituents ◽  
Mentha Piperita ◽  
Antibacterial And Antifungal Activity ◽  
Antibacterial And Antifungal
Sign in / Sign up

Export Citation Format

Share Document