Overall and Sex-Specific Risk Factors for Subjective Cognitive Decline: Findings From the 2015–2018 Behavioral Risk Factor Surveillance System Survey

Author(s):  
Karen Schliep ◽  
Lily Gu ◽  
Kristine Lynch ◽  
Michelle Sorweid ◽  
Michael Varner ◽  
...  

Abstract Background Prior research indicates that at least 35% of Alzheimer’s disease and related dementia risk may be amenable to prevention. Subjective cognitive decline is often the first indication of preclinical dementia, with the risk of subsequent Alzheimer’s disease in such individuals being greater in women than men. We wished to understand how modifiable factors are associated with subjective cognitive decline, and whether differences exist by sex. Methods Data were collected from men and women (45 years and older) who completed the U.S. Behavioral Risk Factor Surveillance System Cognitive Decline Module (2015–2018), n=216,838. We calculated population attributable fractions for subjective cognitive decline, stratified by sex, of the following factors: limited education, deafness, social isolation, depression, smoking, physical inactivity, obesity, hypertension, and diabetes. Our models were adjusted for age, race, income, employment, marital and Veteran status, and accounted for communality among risk factors. Results The final study sample included more women (53.7%) than men, but both had a similar prevalence of subjective cognitive decline (10.6% of women versus 11.2% of men). Women and men had nearly equivalent overall population attributable fractions to explain subjective cognitive decline (39.7% for women versus 41.3% for men). The top three contributing risk factors were social isolation, depression, and hypertension, which explained three-quarters of the overall population attributable fraction. Conclusions While we did not identify any differences in modifiable factors between men and women contributing to subjective cognitive decline, other factors including reproductive or endocrinological health history or biological factors that interact with sex to modify risk warrant further research.

2021 ◽  
pp. 101053952110209
Author(s):  
Uyanga Ganbat ◽  
Yan Yan Wu

Existing research on subjective cognitive decline (SCD) among Native Hawaiians/Other Pacific Islanders (NHOPIs) is limited even though NHOPI adults have the highest prevalence of cardiovascular risk factors. In this study, we investigated SCD disparities among NHOPIs, Asian Americans, and White Americans and its contributing factors utilizing the 2015 and 2017 survey year data from the Behavioral Risk Factor Surveillance System (BRFSS) for Hawai‘i State in the United States. The SCD prevalence was 11.9%, 8.97%, and 7.86% among NHOPIs, Whites, and Asians, respectively. Adjusting for sociodemographic and health behavioral variables, the prevalence ratios (PRs) of SCD were 1.37 (95% confidence interval [CI] = 1.05-1.78) for NHOPI versus Asian and 1.15 (95% CI = 0.89-1.50) for NHOPI versus Whites. The associations were weakened after adjusting for health conditions. Depressive disorders, coronary heart disease or myocardial infarction, stroke, and diabetes were associated with cognitive decline in the multivariate-adjusted model. NHOPIs experienced more SCD-related functional difficulties than other races.


2017 ◽  
Vol 32 (3) ◽  
pp. 129-136
Author(s):  
Mary Adams

Introduction: Estimates of US adults with dementia differ widely and don’t distinguish adults living in the community. Methods: Behavioral Risk Factor Surveillance System data from 120 485 households in 21 states that used a cognitive decline module in 2011 were used. Data for both respondents and other adults with subjective cognitive decline (SCD) were included through proxy responses. Using responses to questions about the receipt of informal care for their SCD and diagnosed dementia, estimates were made for each state. Results: Overall, 2.9% (range: 1.5% in Tennessee to 5.3% in Arkansas) of all noninstitutionalized adults in these states received informal care for their SCD and 0.9% (range: 0.5% in Tennessee to 2.0% in Arkansas) were estimated to have dementia. Limiting results to respondents reduced estimates significantly. Discussion: Combined results for respondents and nonrespondents from a representative telephone survey provide varying estimates of SCD-related measures across states, highlighting the need for state-specific estimates.


2021 ◽  
pp. 263501062110017
Author(s):  
Ya-Ching Huang ◽  
Heather E. Cuevas ◽  
Julie A. Zuñiga ◽  
Alexandra A. García

Purpose The purpose of this study was to examine the prevalence of subjective cognitive decline (SCD) and SCD-related functional limitations among people with diabetes and to identify socioeconomic and comorbidity risk factors associated with SCD. Methods This study analyzed data from the 2017 Behavioral Risk Factor Surveillance System (BRFSS) with background variables (race, gender, education, and age), health-related factors (self-rated health, BMI, insurance, and comorbid conditions), and health behaviors (smoking, exercise, alcohol consumption) entered simultaneously to estimate logistic regression models of SCD. Results Within the sample (n = 5263 adults with diabetes), 48% were age ≥65 years; 50% were male; 55% were non-Hispanic White; and of the 15% who reported having SCD, 57% had functional limitations. Increased odds of reporting SCD were observed among individuals who were Hispanic (odds ratio [OR] = 2.21, P < .001), male (OR = 1.47, P < .01), depressed (OR = 3.85, P < .001), or had arthritis (OR = 1.43, P < .03). Participants with better self-rated health had a reduced likelihood of SCD (OR = 0.51, P < .001). Conclusions Health care providers should assess high-risk patients for self-rated cognitive dysfunction and offer early interventions.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S912-S912
Author(s):  
Kristi M Wisniewski ◽  
Elizabeth M Zelinski

Abstract Participation in risky health behaviors can increase the potential for cognitive decline. Smoking, alcohol consumption, and minimal physical activity are modifiable risk factors associated with worse performance on cognitive assessments; however, the relationship between subjective cognitive decline (SCD) and risky practices has not been assessed. As a potential early indicator of cognitive impairment, SCD may serve as a screening measure for dementia. The Behavioral Risk Factor Surveillance System is an annual, self-reported telephone survey of Americans that includes fifteen core and twenty-five optional sections. The present study included Behavioral Risk Factor Surveillance System participants age 45 or older who completed the core and cognitive decline modules in 2015 (n=147,243). Roughly 11% of participants endorsed worsening memory in the previous year. Logistic regression examined the impact of smoking, drinking, and inactivity on self-reported cognitive decline. Current or former smokers had greater odds of endorsing cognitive decline compared to those who never smoked (OR=1.4; 95% CI: 1.27-1.52). Individuals who consumed at least one alcoholic beverage in the previous month had lower SCD odds compared to non-drinkers (OR=0.8; 95% CI: 0.72-0.87). Respondents who engaged in little to no physical activity had greater odds of endorsing cognitive decline compared to active respondents (OR=1.4; 95% CI: 1.31-1.57). Individuals who endorsed cognitive decline engaged in unhealthy habits such as smoking or inactive lifestyles; however, low to moderate alcohol consumption may be beneficial for cognitive functioning.


2020 ◽  
Vol 41 (3) ◽  
pp. 420-431
Author(s):  
Katie Cueva ◽  
Andrea Fenaughty ◽  
Jessica Aulasa Liendo ◽  
Samantha Hyde-Rolland

Chronic diseases with behavioral risk factors are now the leading causes of death in the United States. A national Behavioral Risk Factor Surveillance System (BRFSS) monitors those risk factors; however, there is a need for national and state evaluations of chronic disease surveillance systems. The Department of Health and Human Services/Centers for Disease Control and Prevention (CDC) has developed a framework on evaluating noncommunicable disease–related surveillance systems; however, no implementation of this framework has yet been published. This article describes the process of, and offers lessons learned from, implementing the evaluation framework to assess the Alaska BRFSS. This implementation evaluation may inform assessments of other state and regional chronic disease surveillance systems and offers insight on the positive potential to consult key stakeholders to guide evaluation priorities.


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