Extraskeletal Osteosarcoma After Postoperative Radiotherapy for a Keloid: a Case Report
Abstract Background: The current standard treatment for keloids is a combination of surgery and postoperative radiotherapy with 8–25 Gy. Case presentation: Our case was a 75-year-old patient who developed a swollen mass in her chest 20 years after excision of a chest keloid followed by 32 Gy postoperative radiotherapy. After resection of the swollen mass, pathology indicated extraskeletal osteosarcoma. Conclusions: Six putative cases of carcinogenesis after postsurgical radiotherapy for keloid have been reported over the last 70 years. To our knowledge, this is the first case of post-keloid radiotherapy carcinogenesis that meets the definition of a radiation-induced sarcoma. The risk of secondary carcinogenesis after postsurgical radiotherapy for keloid is small but must be explained to the patient.