scholarly journals Comparison of postoperative changes in radial peripapillary capillary density between femtosecond laser-assisted cataract surgery and conventional phacoemulsification surgery using optical coherence tomography angiography

2020 ◽  
Author(s):  
Hong Zhang ◽  
Liangzhang Tan ◽  
Fang Tian ◽  
Xue Gong ◽  
Lu Chen ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Femtosecond Laser ◽  
Cataract Surgery ◽  
Optical Coherence Tomography Angiography ◽  
Capillary Density ◽  
Optical Coherence ◽  
Time Points ◽  
Postoperative Changes ◽  
Age Related ◽  
Radial Peripapillary Capillary

Abstract Purpose: To assess differences in post-surgical radial peripapillary capillary (RPC) density changes between femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification surgery (CPS) using optical coherence tomography angiography (OCTA).Methods: Fifty-two eyes of 52 patients were enrolled in this study. Depending on their preference, patients with age-related cataract underwent FLACS or CPS. Automated peripapillary maps and capillary density calculations were retrospectively evaluated using OCTA before surgery and on day 1 and months 1 and 3 postoperatively.Results: The whole-image and peripapillary RPC densities were lower at day 1 and months 1 and 3 postoperatively than before surgery in the FLACS group (all P < 0.05). However, there was no change in the whole-image and peripapillary RPC densities before and after surgery, across different time-points, in the CPS group (all P > 0.05). Moreover, comparison of data corresponding to each time-point between the FLACS and CPS groups showed no significant differences in any metrics prior to surgery (all P > 0.05). However, the whole-image and peripapillary RPC densities were significantly different at day 1 and month 1 after the surgery (all P < 0.05). At the 3-month follow-up, we did not observe significant differences (all P > 0.05). Conclusions: Postoperative whole-image and peripapillary RPC densities were lower in the FLACS group than in the CPS across time-points. While the short-term RPC density changes were resolved, to elucidate the long-term implications of FLACS, especially for eyes with glaucoma, diabetic retinopathy, etc., further investigations are required.

scholarly journals Changes in Retinal Vasculature and Thickness After Femtosecond Laser-assisted Cataract Surgery and Conventional Cataract Surgery Using Optical Coherence Tomography Angiography

2022 ◽  
Author(s):  
Hong Zhang ◽  
Liangzhang Tan ◽  
Fang Tian ◽  
Xue Gong ◽  
Lu Chen ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Femtosecond Laser ◽  
Cataract Surgery ◽  
Optical Coherence Tomography Angiography ◽  
Macular Thickness ◽  
Retinal Vasculature ◽  
Optical Coherence ◽  
Age Related

Abstract Purpose To assess the changes in retinal vasculature and thickness after femtosecond laser-assisted cataract surgery (FLACS) using optical coherence tomography angiography (OCTA).Methods Fifty-six eyes of 56 patients with age-related cataract were enrolled in this study. Patients were divided into FLACS or conventional phacoemulsification surgery (CPS) due to the choice of operation. Vessel density (VD) and thickness at the macular area and optic nerve head (ONH) were checked by OCTA at baseline and at 1 day, 1 month and 3 months after cataract surgery.Results In the FLACS group: The radial peripapillary capillary (RPC) density displayed a significant reduction during the follow-up (P < 0.05), even when the retinal nerve fiber layer (RNFL) thickness was not significantly changed. There was a significant negative correlation between the changes in RPC density and femtosecond laser-assisted pre-treatment time (FLAPT) at 1 day and 1 month after cataract surgery respectively (both P < 0.05). At 3 months postoperatively, the macular thickness had a significant increase in all regions (all P < 0.05). In the CPS group, the retinal VD and thickness did not show statistically significant changes in all regions during the follow-up (all P > 0.05). However, the best corrected visual acuity (BCVA) was significantly improved in both groups postoperatively (both P < 0.001).Conclusions OCTA provided a promising analysis of retinal vascular alterations, demonstrating the reduction of RPC density and the increase of macular thickness after FLACS. However, these changes had no effect on the improvement of visual acuity after cataract surgery.

Retinal Vascular changes in Femtosecond Laser-Assisted Cataract Surgery by Optical Coherence Tomography Angiography

2021 ◽  
Author(s):  
Hong Zhang ◽  
Liangzhang Tan ◽  
Fang Tian ◽  
Xue Gong ◽  
Lu Chen ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Femtosecond Laser ◽  
Cataract Surgery ◽  
Optical Coherence Tomography Angiography ◽  
Treatment Time ◽  
Macular Thickness ◽  
Optical Coherence ◽  
Age Related

Abstract Purpose To assess the changes in retinal vasculature and thickness after femtosecond laser-assisted cataract surgery (FLACS) using optical coherence tomography angiography (OCTA).Methods Fifty-six eyes of 56 patients with age-related cataract were enrolled in this study. Patients were divided into FLACS or conventional phacoemulsification surgery (CPS) due to the choice of operation. Vessel density (VD) and thickness at the macular area and optic nerve head (ONH) were checked by OCTA at baseline and at 1 day, 1 month and 3 months after cataract surgery.Results In the FLACS group: The radial peripapillary capillary (RPC) density displayed a significant reduction during the follow-up (P < 0.05), even when the retinal nerve fiber layer (RNFL) thickness was not significantly changed. There was a significant negative correlation between the changes in RPC density and femtosecond laser-assisted pre-treatment time (FLAPT) at 1 day and 1 month after cataract surgery respectively (both P < 0.05). At 3 months postoperatively, the macular thickness had a significant increase in all regions (all P < 0.05). In the CPS group, the retinal VD and thickness did not show statistically significant changes in all regions during the follow-up (all P > 0.05). However, the best corrected visual acuity (BCVA) was significantly improved in both groups postoperatively (both P < 0.001).Conclusions OCTA provided a promising analysis of retinal vascular alterations, demonstrating the reduction of RPC density and the increase of macular thickness after FLACS. However, these changes had no effect on the improvement of visual acuity after cataract surgery.

Measurement of Radial Peripapillary Capillary Density in the Normal Human Retina Using Optical Coherence Tomography Angiography

2017 ◽  
Vol 26 (3) ◽  
pp. 241-246 ◽  
Author(s):  
Tarannum Mansoori ◽  
Jayanthi Sivaswamy ◽  
Jahnavi Sai Gamalapati ◽  
Satish Gooty Agraharam ◽  
Nagalla Balakrishna
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Capillary Density ◽  
Human Retina ◽  
Optical Coherence ◽  
Normal Human ◽  
Radial Peripapillary Capillary

scholarly journals Retinal microvasculature alterations in myopic anisometropia on optical coherence tomography angiography

2020 ◽  
Author(s):  
Xiaorong Li ◽  
liangzhang Tan ◽  
lu Chen ◽  
shaochong Bu ◽  
yuanfeng jiang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Early Stage ◽  
Capillary Density ◽  
Vessel Density ◽  
Foveal Avascular Zone ◽  
Optical Coherence ◽  
Retinal Microvasculature ◽  
Contralateral Eye ◽  
Radial Peripapillary Capillary

Abstract Background: In myopic anisometropia, investigation of alterations in the retinal capillary network may reveal the myopic pathophysiology and facilitate development of improved treatment and prevention strategies. This study aimed to evaluate alterations in retinal vessel density in patients with myopic anisometropia using optical coherence tomography angiography. Methods: Twenty-one patients with myopic anisometropia were divided into longer axial eye and contralateral eye groups, based on their axial length measurement by an IOL Master system. Automated macular and peripapillary maps and vessel density calculations were evaluated using optical coherence tomography angiography, and the findings were compared between groups. Results: The longer axial eye group had higher superficial macular vessel density (47.06±3.03% vs. 43.71±3.20%, respectively; P <0.001) and lower radial peripapillary capillary density (50.11±3.56% vs. 52.34±2.74%, respectively; P =0.013) than did the contralateral eye group. The spherical equivalent negatively correlated with the superficial macular vessel density ( P =0.021) and superficial parafoveal vessel density ( P =0.014). No significant differences were detected in the deep macular vessel density (49.12±6.32% vs. 46.73±5.30%, respectively; P >0.05), choriocapillary perfusion area (1.92±0.18 mm 2 vs.1.90±0.19 mm 2 , respectively; P >0.05), or foveal avascular zone area (0.27±0.07 mm 2 vs. 0.28±0.07 mm 2 , respectively; P >0.05) between groups. Conclusion: The superficial macular vessel density and radial peripapillary capillary density could be used as indicators to monitor myopic anisometropia development during early-stage retinopathy.

scholarly journals The Spectrum of Central Choriocapillaris Abnormalities on Swept-Source Optical Coherence Tomography Angiography in the Fellow Eye of Unilateral Exudative Age-Related Macular Degeneration Patients: From Flow Deficits to Subclinical Non-Exudative Neovascularization

2021 ◽  
Vol 10 (12) ◽  
pp. 2658
Author(s):  
Alexis Khorrami Kashi ◽  
Eric Souied ◽  
Selim Fares ◽  
Enrico Borrelli ◽  
Vittorio Capuano ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Optical Coherence Tomography Angiography ◽  
Clinical Findings ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Swept Source ◽  
Exudative Amd ◽  
Age Related ◽  
Fellow Eyes

We evaluated the spectrum of choriocapillaris (CC) abnormalities in the fellow eyes of unilateral exudative age-related macular degeneration (AMD) patients using swept-source optical coherence tomography angiography (SS-OCTA). Fellow eyes of unilateral exudative AMD patients were prospectively included between May 2018 and October 2018. Patients underwent a multimodal imaging including a SS-OCTA. Demographics and clinical findings were analyzed. The estimated prevalence of macular neovascularization (MNV) was computed. Number and size of flow deficits (FDs) and percentage of flow deficits (FD%) were computed on the compensated CC flow images with the Fiji software. We included 97 eyes of 97 patients (mean age was 80 ± 7.66 years, 39 males, 58 females). The prevalence of MNV in the studied eyes was 8.25% (8/97 eyes). In the 89 non-neovascular eyes, FD% averaged 45.84% ± 11.63%, with a corresponding total area of FDs of 4.19 ± 1.12 mm2. There was a higher prevalence of drusenoid pigment epithelial detachment in eyes with subclinical neovascularization (p = 0.021). Fellow eyes with unilateral exudative AMD encompassed a series of CC abnormalities, from FDs of the aging CC to subclinical non-exudative MNV.

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