scholarly journals Relationship between the Severity of Endometriosis Symptoms (Dyspareunia, Dysmenorrhea and Chronic pelvic pain) with the Spread of the Disease on Ultrasound

2020 ◽  
Author(s):  
Elham Kor ◽  
Seyed Reza Saadat Mostafavi ◽  
Zahra Ahmadian Mazhin ◽  
Adeleh Dadkhah ◽  
Anis Kor ◽  
...  

Abstract Objectives: About 10-15% of women of childbearing age have endometriosis. The present study aimed to investigate the relationship between the severity of symptoms of endometriosis and the spread as well as the stage of the disease on ultrasonography. The present cross-sectional study evaluates the relationship between the severity of endometriosis symptoms and the spread of disease on ultrasonography in patients with endometriosis.Results: Considering different analyses, the cumulative size of posterior Deep Infiltrative Endometriosis (DIE) (less than 1 cm) is significantly correlated with minimal severity of dyspareunia and chronic pelvic pain. The incidence of dyspareunia was more prevalent in patients with complete stenosis of Douglas pouch than those with incomplete stenosis. Furthermore, the incidence of severe and very severe pain in patients with Douglas pouch stenosis is relatively higher than that in patients without stenosis. Only dyspareunia is related to the stage of endometriosis, and patients with dyspareunia are five times more at risk of a higher stage of the disease. The severity of dyspareunia is related to the stage of endometriosis and the severity of Douglas pouch stenosis. The results showed a correlation between chronic pelvic pain and r-ASRM score (revised American Society for Reproductive Medicine score).

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Elham Kor ◽  
Seyed Reza Saadat Mostafavi ◽  
Zahra Ahmadian Mazhin ◽  
Adeleh Dadkhah ◽  
Anis Kor ◽  
...  

Abstract Objectives About 10–15% of women of childbearing age have endometriosis. The present study aimed to investigate the relationship between the severity of symptoms of endometriosis and the spread as well as the stage of the disease on ultrasonography. The present cross-sectional study evaluates the relationship between the severity of endometriosis symptoms and the spread of disease on ultrasonography in patients with endometriosis. Results Considering different analyses, the cumulative size of posterior deep infiltrative endometriosis (DIE) (less than 1 cm) is significantly correlated with minimal severity of dyspareunia and chronic pelvic pain. The incidence of dyspareunia was more prevalent in patients with complete stenosis of Douglas pouch than those with incomplete stenosis. Furthermore, the incidence of severe and very severe pain in patients with Douglas pouch stenosis is relatively higher than that in patients without stenosis. Only dyspareunia is related to the stage of endometriosis, and patients with dyspareunia are five times more at risk of a higher stage of the disease. The severity of dyspareunia is related to the stage of endometriosis and the severity of Douglas pouch stenosis. The results showed a correlation between chronic pelvic pain and r-ASRM score (revised American Society for Reproductive Medicine score).


2020 ◽  
Author(s):  
Elham Kor ◽  
Seyed Reza Saadat Mostafavi ◽  
Zahra Ahmadian Mazhin ◽  
Adeleh Dadkhah ◽  
Anis Kor ◽  
...  

Abstract Objectives: The prevalence of endometriosis among women of childbearing age is about 10-15%. The present study aimed to investigate the relationship between the severity of symptoms of endometriosis and the spread as well as the stage of the disease on ultrasonograghy. The present cross-sectional study evaluates the relationship between the severity of endometriosis symptoms and the spread of disease on ultrasonography in patients with endometriosis.Results: Considering different analyses, the cumulative size of posterior Deep infiltrative endometriosis (DIE) (less than 1 cm) is significantly correlated with minimal severity of dyspareunia and chronic pelvic pain. The incidence of dyspareunia was more prevalent in patients with complete stenosis of Douglas pouch than those with incomplete stenosis... Further, the incidence of severe and very severe pain in patients with Douglas pouch stenosis is relatively higher than that in patients without stenosis. Only dyspareunia is related to the stage of endometriosis, and patients with dyspareunia are 5 times more at risk of a higher stage of the disease. The severity of dyspareunia is related to the stage of endometriosis and the severity of Douglas pouch stenosis. The results show the correlation between chronic pelvic pain and r-ASRM score (revised American Society for Reproductive Medicine score).


2020 ◽  
Author(s):  
Elham Kor ◽  
Seyed Reza Saadat Mostafavi ◽  
Zahra Ahmadian Mazhin ◽  
Adeleh Dadkhah ◽  
Anis Kor ◽  
...  

Abstract Objectives The prevalence of endometriosis among women of childbearing age is about 10–15%. Although many patients with endometriosis do not have any symptoms, they may suffer from dysmenorrhea, dyspareunia, and chronic pelvic pain. our aim of this study is to investigate the relationship between the severity of symptoms of endometriosis with the spread of disease on ultrasonography as well as the stage of the disease. Results Regarding the various analyzes were performed, the cumulative size of posterior DIE less than 1 cm significantly correlated with minimal severity of dyspareunia and chronic pelvic pain. The incidence of dyspareunia was more in patients with complete stenosis of Douglas pouch comparing with cases with incomplete Douglas pouch stenosis. The incidence of severe and very severe pain in patients with Douglas pouch stenosis is relatively higher than patients without stenosis. This study demonstrated only dyspareunia is related to the stage of endometriosis and patients with dyspareunia are 5 times more at risk of a higher stage of the disease.


Author(s):  
Heidi K. Byrne ◽  
Jack H. Wilmore

The present cross-sectional study was designed to investigate the relationship between exercise training and resting metabolic rate (RMR). The focus of this investigation was to compare RMR in aerobically trained (AT), resistance trained (RT), and untrained (UNT) women. Subjects were also classified as highly trained (HT), moderately trained (MT), or untrained (UNT) in order to examine the relationship between RMR and level of training. Sixty-one women between the ages of 18 and 46 years volunteered to serve as subjects in this study. Each subject completed measurements of body composition, maximal oxygen uptake (V̇O2max), and two consecutive measurements of RMR. The data presented show that there was no significant difference in resting metabolic rate between resistance-trained, aerobically trained, and control subjects. However, when grouped by intensity of training, there was a trend for an increased resting metabolic rate (kcal/day) in the highly trained subjects, regardless of mode of training.


2020 ◽  
Vol 70 (700) ◽  
pp. e778-e784
Author(s):  
Elizabeth Lovegrove ◽  
John Robson ◽  
Patricia McGettigan

BackgroundThe teratogenic risks of angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are well documented, but prescribing these in younger women in primary care is becoming increasingly frequent.AimTo record how frequently women of childbearing age, who are prescribed an ACE inhibitor or ARB, receive preconception advice and/or are prescribed contraception, and how many pregnancies, terminations, and miscarriages occur in this population. Additionally, to ascertain whether patterns in the above differ across age groups.Design and settingCross-sectional study conducted among patients from 141 general practices in East London.MethodWomen aged 15–45 years who were issued a prescription for an ACE inhibitor or ARB between 1 October 2018 and 1 January 2019 inclusive were included. An electronic search strategy was designed to extract pseudonymised data concerning preconception and contraception advice, contraception, and pregnancies from the electronic clinical system; this was applied to the selected cohort on 1 January 2019. Data were analysed in 5-year age groups.ResultsOf 302 939 women aged 15–45 years, 2651 (0.9%) were prescribed an ACE inhibitor or an ARB in a 3-month period. Of these, 2159 (81.4%) had no advice and no contraception prescription recorded, 35 (1.3%) had preconception advice recorded, and 230 (8.7%) had contraception advice recorded. A total of 100 pregnancies and 21 terminations/miscarriages were recorded in the 12 months preceding the index date (1 January 2019).ConclusionThis study found that the recording of pre-pregnancy advice and contraception in women of childbearing age who were prescribed an ACE inhibitor or an ARB was suboptimal; this may place women and their babies at risk of exposure to teratogens during pregnancy. The findings indicate that there is a need for improved safety strategies based in primary care.


BMJ Open ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. e030873 ◽  
Author(s):  
Rihwa Choi ◽  
Yejin Oh ◽  
Youngju Oh ◽  
Sung Ho Kim ◽  
Sang Gon Lee ◽  
...  

ObjectivesThe aim of this study was to investigate the immunity against rubella using the serological status of rubella-specific IgG antibodies (antirubella IgG) in Korean women of childbearing age (15–49 years).DesignRetrospective cross-sectional study.SettingPopulation-based cross-sectional study in South Korea.ParticipantsBetween January 2010 and December 2017, test results from Korean women aged 15–49 years who had visited an obstetric private clinic (nationwide institutions) and had requested rubella-specific IgG antibody tests from Green Cross Laboratories were obtained from the laboratory information system.ResultsBetween 2010 and 2017, antirubella IgG test results from 328 426 Korean women aged 15–49 years who had visited private obstetric clinics (1438 institutions nationwide) were retrospectively analysed by tested year, age, cohort and geographic regions. Over the 8-year study period, the rate of unimmunised women ranged from 7.8% to 9.7%. Multivariable-adjusted logistic regression models showed that the odds of being immune to rubella (positive and equivocal results of antirubella IgG test) were lower in 2017 compared with 2010, in women in their 40s, in a pre-catch-up cohort and in women living in Incheon, Busan, South Gyeongsang, North and South Jeolla and Jeju provinces (p<0.0001).ConclusionsIn consideration of the factors associated with prevalence of women unimmunised to rubella, future public health efforts should be focused on catch-up activities. The results of this study could be used to strengthen disease control and prevent rubella, including a nationwide immunisation programme.


2020 ◽  
Vol 12 (2) ◽  
pp. 77-85
Author(s):  
Robert Markham ◽  
Georgina M Luscombe ◽  
Frank Manconi ◽  
Ian S Fraser

Introduction: The purpose of this study was to investigate the detailed nature of menstrual characteristics, bleeding and other symptoms in women with and without endometriosis. Pelvic pain symptoms in this cohort have been reported elsewhere. Method: This is a self-administered cross-sectional study and was conducted using a structural questionnaire. A total of 737 women completed the study: women with endometriosis (n = 529) and with no current gynaecological complaint, ‘control’ (n = 208). Results: Some of the key findings in this study included significant differences between the control and endometriosis subjects in terms of bleeding symptoms, increased length and heaviness of menses, rectal and bladder bleeding, infertility and obstetric complications which were all more common in the endometriosis group. Other symptoms found to have a highly significant positive association with endometriosis included abdominal bloating, low resistance to infection, fatigue, increased urinary frequency, diarrhoea and constipation (p < 0.000). Data were cross-tabulated to examine the association of a number of symptoms to each other. The relationship of symptoms to a range of psychosocial factors was investigated to determine how the effects of endometriosis impacted on the life of subjects. Most women reported that endometriosis sometimes or often interfered with daily aspects of their life. Conclusion: The range of non-pain symptoms in women with endometriosis was generally much more diverse and extensive than recognised by most clinicians.


PLoS ONE ◽  
2016 ◽  
Vol 11 (5) ◽  
pp. e0155801 ◽  
Author(s):  
Minxue Shen ◽  
Hongzhuan Tan ◽  
Shujin Zhou ◽  
Ravi Retnakaran ◽  
Graeme N. Smith ◽  
...  

2010 ◽  
Vol 4 (5) ◽  
pp. 217
Author(s):  
Suhartono Suhartono ◽  
Dharminto Dharminto

Wanita bermukim di daerah pertanian berisiko terpajan pestisida yang dapat berakibat hipotiroidisme yang pada kehamilan dapat menyebabkan gangguan tumbuh-kembang janin. Tujuan penelitian ini adalah mengetahui angka kejadian keracunan pestisida dan hipotiroidisme pada wanita usia subur di daerah pertanian. Penelitian ini menggunakan disain penelitian cross-sectional dan 26 WUS terpilih sebagai subjek secara acak. Semua subjek dilakukan pengukurankadar TSH, fT4 dan enzim kolinesterase, sementara kadar T3, UEI, dan Pb darah diukur pada sub-sampel. Penderita dinyatakan keracunan pestisida apabila ditemukan kadar enzim kolinesterase <3,9 μg/L dan dinyatakan hipotiroidisme apabila kadar TSH >4,5 μIU/L. Penelitian ini menemukan rerata kadar kolinesterase adalah 7,26 (±1,28) dengan kisaran nilai 5,33-9,39 μg/L; rerata kadar TSH adalah 5,09 (±6,14), dengan kisaran nilai 0,47-31,73μIU/L; rerata kadar fT4 adalah 15,18 (±2,09), dengan kisaran nilai 8,73-18,87 pmol/L; rerata kadar T3 adalah 1,75 (±0,51), dengan kisaran nilai 1,24-2,95 pmol/L. Prevalensi keracunan pestisida pada WUS 0,0% dan prevalensi hipotiroidisme 46,2%.Kata kunci : Pestisida, hipotiroidisme, wanita usia subur, daerah pertanianAbstractWomen lived in agricultural areas are risk to suffer various disorders due to pesticides exposure such as hypothyroidism. Hypothyroidism causes growth and development disorders of fetus. The aim of the study is to find out the prevalence of pesticide poisoning and hypothyroidism in women of childbearing age in agricultural areas. Cross-sectional study was conducted and 26 women of childbearing age were selected randomly. TSH, fT4 and cholinesterase enzymelevels were measured in all subjects, while levels of T3, UEI and blood Pb were measured in the sub-sample. Pesticide poisoning is determined if the levels of enzymes cholinesterase <3.9 μg/L and determined as hypothyroidism if the TSH >4.5 μIU/L. This study showed that mean of cholinesterase levels was 7.26 (± 1.28), range of values 5.33-9.39 μg/L; mean of TSH levels was 5.09 (± 6.14), range of values 0.47-31.73 μIU/L; mean of fT4 level was 15.18 (±2.09), range of values 8.73-18.87 pmol/L; mean of T3 levels was 1.75 (±0.51), range of values 1.24-2.95 pmol/L. The prevalence of pesticide poisoning in childbearing women was 0.0% and prevalence of hypothyroidism was 46.2%.Key words : Pesticide, hypothyroidism, women of childbearing age, agricultural area


2020 ◽  
Vol 10 (04) ◽  
pp. 369-392
Author(s):  
Christelle Momdjo M’bobda ◽  
Judith Laure Ngondi ◽  
Françoise Raïssa Ntentie ◽  
Boris Ronald Tonou Tchuente ◽  
Maxwell Wandji Nguedjo ◽  
...  

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