scholarly journals Urinary Phenols and Parabens Metabolites with Cardiovascular Disease in United States Adult

2021 ◽  
Author(s):  
Ting Yin ◽  
Xu Zhu ◽  
Iokfai Cheang ◽  
Yufei Zhou ◽  
Shengen Liao ◽  
...  
Keyword(s):  
Heart Attack ◽  
Cross Sectional Study ◽  
Spline Regression ◽  
Multivariate Logistic Regression ◽  
Cvd Risk ◽  
Cross Sectional ◽  
Health And Nutrition ◽  
The Us ◽  
Nationally Representative ◽  
Positive Correlations

Abstract Environmental health has begun to examine the effects of higher-order chemical combinations. The current literature lacks studies exploring associations between multiple organic chemicals mixture and cardiometabolic disease (CVD). This study aimed to evaluate associations between urinary phenol and paraben metabolites and total and individual CVD among a nationally representative sample of adults in the US. This cross-sectional study analyzed 7 urinary chemicals detected among the general population from the 2005–2016 National Health and Nutrition Examination Survey (NHANES, n = 10,428). Multivariate logistic regression and weighted quantile sum (WQS) regression were applied to examine relationships between phenol and paraben metabolites, alone and combined, and total and individual CVD prevalence. WQS regression showed that phenol and paraben indices were independently correlated with total CVD (adjusted odds ratios [OR]: 1.16; 95% confidence interval [CI]:1.06–1.28; P = 0.002), angina (adjusted OR: 1.30; 95% CI: 1.07–1.59; P = 0.009), and heart attack (adjusted OR: 1.30; 95% CI: 1.12–1.51, P < 0.001). Urinary bisphenol A (URBPA, weight = 0.636) was the most heavily weighted component in the total CVD model. Compared with the lowest quartile, URBPA (OR: 1.52; 95% CI: 1.20–1.91; P = 0.001) levels in the highest quartile were independently associated with increased total CVD. Restricted cubic spline regression demonstrated positive correlations and non-linear associations between URBPA and both total CVD (P for nonlinearity = 0.032) and individual CVD (heart attack; P for nonlinearity = 0.031). Our findings suggested that high combined levels of phenols and parabens are associated with an increased CVD risk, with the URBPA contributing the highest risk.

scholarly journals Ultra-processed foods and added sugars in the US diet: evidence from a nationally representative cross-sectional study

BMJ Open ◽  
2016 ◽  
Vol 6 (3) ◽  
pp. e009892 ◽  
Author(s):  
Eurídice Martínez Steele ◽  
Larissa Galastri Baraldi ◽  
Maria Laura da Costa Louzada ◽  
Jean-Claude Moubarac ◽  
Dariush Mozaffarian ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Processed Foods ◽  
Sectional Study ◽  
Cross Sectional ◽  
Added Sugars ◽  
The Us ◽  
Nationally Representative

scholarly journals Urinary 2,5-dicholorophenol and 2,4-dichlorophenol concentrations and prevalent disease among adults in the National Health and Nutrition Examination Survey (NHANES)

2018 ◽  
Vol 76 (3) ◽  
pp. 181-188 ◽  
Author(s):  
Mary R Rooney ◽  
Pamela L Lutsey ◽  
Parveen Bhatti ◽  
Anna Prizment
Keyword(s):  
National Health ◽  
Linear Trend ◽  
Nutrition Examination Survey ◽  
Cvd Risk ◽  
Cross Sectional ◽  
Adverse Health Outcomes ◽  
Representative Study ◽  
Health And Nutrition ◽  
Prevalent Disease ◽  
Nationally Representative

ObjectiveTo test cross-sectional associations between urinary concentrations of 2,5-dichlorophenol (2,5-DCP) and 2,4-dichlorophenol (2,4-DCP) with the prevalence of cardiovascular disease (CVD), cancer, lung disease, thyroid problems and liver conditions.MethodsLogistic regression was used to evaluate associations of urinary concentrations of 2,5-DCP and 2,4-DCP with prevalence of various medical conditions among 3617 National Health and Nutrition Examination Survey participants from 2007–2008 and 2009–2010. ORs and 95% CIs for each disease were estimated. All regression models were adjusted for urinary creatinine.ResultsWe observed a monotonically increasing association between quartiles of 2,5-DCP and prevalence of CVD. After adjustment for sociodemographic and lifestyle characteristics, participants with the highest versus lowest quartile of urinary 2,5-DCP had an OR=1.84 (95% CI 1.26 to 2.70) (p linear trend=0.006). The association was similar with further adjustment for established clinical CVD risk factors. Higher 2,5-DCP was also associated with prevalence of all cancers combined (ORQ4 vs Q1=1.50 (95% CI 1.00 to 2.26); p trend=0.05) and, in exploratory analyses, with gynaecological cancers (ORQ4 vs Q1=4.15 (95% CI 1.51 to 11.40; p trend=0.01)). No associations were detected between 2,5-DCP and lung diseases, thyroid problems or liver conditions, nor between 2,4-DCP and prevalent disease.ConclusionIn this nationally representative study, higher urinary 2,5-DCP concentrations were associated with greater prevalence of CVD and all cancers combined. Further examination may be warranted to assess whether chronic exposure to 2,5-DCP is associated with incidence of adverse health outcomes.

scholarly journals Consumptions of plain water, moisture in foods and beverages, and total water in relation to dietary micronutrient intakes and serum nutrient profiles among US adults

2014 ◽  
Vol 18 (7) ◽  
pp. 1180-1186 ◽  
Author(s):  
Meng Yang ◽  
Ock K Chun
Keyword(s):  
Water Intake ◽  
Cross Sectional Study ◽  
Plain Water ◽  
Total Water ◽  
Cross Sectional ◽  
Negatively Associated ◽  
Health And Nutrition ◽  
The Us ◽  
Nutrient Profiles ◽  
Total Water Intake

AbstractObjectiveTo investigate water contributors in relation to dietary and serum micronutrient profiles.DesignA cross-sectional study. The main exposures were water contributors. Selected dietary and serum micronutrient levels were outcome measures.SettingsThe US population and its subgroups.SubjectsUS adults (n 2691) aged ≥20 years from the National Health and Nutrition Examination Survey 2005–2006.ResultsThe daily mean total water intake was 3·1 (se 0·047) litres, with 68 % of adults consuming below the Adequate Intake level. Total water intake was higher in adults with higher BMI and physical activity, those taking dietary supplements and alcohol consumers (P < 0·05). Plain water intake was positively associated with food moisture and negatively with beverage moisture (P < 0·001). Beverage moisture was negatively associated with food moisture (P < 0·001). In multivariate regression analyses, plain water and food moisture intakes were positively associated with Fe, Ca, vitamins A, B, C, E and K and carotenoid intakes (P < 0·05). However, beverage moisture was unrelated to Ca, niacin and vitamin B6 intakes, and negatively associated with Fe, vitamin A, folate, vitamins C, E and K and carotenoid intakes (P < 0·05). Concentrations of serum vitamins A and C and carotenoids increased with plain water and food moisture intakes (P < 0·05) but decreased (P < 0·01) or were unrelated to beverage moisture intake.ConclusionsVarious contributors of total water intake differed in their associations with dietary and serum micronutrient profiles in US adults. The study provides evidence of plain water benefits on micronutrient adequacy over beverages.

scholarly journals Age-related Smell and Taste Impairments and Vitamin D Associations in the U.S. Adults National Health and Nutrition Examination Survey

Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 984
Author(s):  
Galya Bigman
Keyword(s):  
Vitamin D ◽  
National Health ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Nutritional Deficiencies ◽  
Nutrition Examination Survey ◽  
Cross Sectional ◽  
Health And Nutrition ◽  
Age Related ◽  
The Us

Smell and taste decline with aging, and markedly deteriorate when nutritional deficiencies occur. This study aims to examine the associations between Vitamin D (VD) deficiency and smell and taste impairments among adults. This paper details a cross-sectional study utilizing data from the US National Health and Nutrition Examination Survey (NHANES, 2013–2014.). Smell impairment was assessed by the Pocket Smell Test and defined as failing to correctly identify six or more of the eight odors. Taste impairment was defined as failing to correctly identify quinine or sodium chloride. VD was measured as serum 25-hydroxyvitamin. Multivariable weighted logistic regressions were utilized. Adjusted odds ratio (OR) and 95% confidence interval (CI) were presented. Overall, 2216 (smell sample) and 2636 (taste sample) participants were included, aged between 40 and 80 years old. Of those, 18.3% had taste impairment, 12.2% had smell impairment, and 20% had VD deficiency (<20 ng/mL). Compared to participants with sufficient VD (>30 ng/mL), those with VD deficiency were more likely by 39% to report a higher prevalence of smell impairment (OR = 1.39, 95%CI: 1.02–1.89); and only participants aged 70–80 years with VD inadequacy (20–30 ng/mL) were more likely by 96% to report a higher prevalence of taste impairment (OR = 1.96, 95%CI: 1.35–1.85). VD may have a significant role in age-related smell impairment in adults aged 40 years or older, and in age-related taste impairment in the elderly aged 70–80 years.

scholarly journals Trends in socioeconomic inequalities in five major risk factors for cardiovascular disease in the Korean population: a cross-sectional study using data from the Korea National Health and Nutrition Examination Survey, 2001–2014

BMJ Open ◽  
2017 ◽  
Vol 7 (5) ◽  
pp. e014070 ◽  
Author(s):  
Yoon Jung Kim ◽  
Ji Sung Lee ◽  
Juri Park ◽  
Dong Seop Choi ◽  
Doo Man Kim ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cross Sectional Study ◽  
Socioeconomic Inequalities ◽  
Korean Women ◽  
Sectional Study ◽  
Cvd Risk Factors ◽  
Cvd Risk ◽  
Cross Sectional ◽  
Health And Nutrition ◽  
Obesity And Diabetes

ObjectivesTo examine trends in socioeconomic inequalities in major cardiovascular disease (CVD) risk factors among the Korean population.DesignCross-sectional study.SettingA nationally representative population survey database.ParticipantsA total of 42 725 Koreans, aged 25–64 years, who participated in the Korean National Health and Nutrition Examination Survey (KNHANES) II (2001) to VI (2013–2014).Main outcome measuresTrends in socioeconomic inequalities in five major CVD risk factors (smoking, obesity, diabetes, hypertension and hypercholesterolaemia).ResultsGender differences were noted in the time trends in socioeconomic inequalities in smoking, obesity, diabetes and hypertension. Among men, low socioeconomic status (SES) was associated with higher prevalence of smoking, but not with obesity, diabetes or hypertension. The magnitudes of socioeconomic inequalities in smoking, obesity and diabetes remained unchanged, and the magnitude of the inequality in hypertension decreased over time. However, among women, low SES was associated with higher prevalence of smoking, obesity, diabetes and hypertension. Time trends towards increasing socioeconomic inequalities, measured by income, in smoking, obesity and diabetes were found in women. Unlike the other CVD risk factors, hypercholesterolaemia was not associated with socioeconomic inequality.ConclusionsSES had a stronger impact on major CVD risk factors among Korean women than men. Moreover, socioeconomic inequalities in smoking, obesity and diabetes worsened among Korean women over time. Public policies to prevent smoking, obesity and diabetes in women with lower SES are needed to address inequalities.

scholarly journals Cross-sectional study of perceived neighborhood collective efficacy and risk of adhd among a nationally-representative sample of children

2015 ◽  
Vol 2 (1) ◽  
pp. 71 ◽  
Author(s):  
Chris Derauf ◽  
Diana Pandey ◽  
Juliette T. Liesinger ◽  
Euijung Ryu ◽  
Jeanette Y. Ziegenfuss ◽  
...  
Keyword(s):  
Risk Factors ◽  
Built Environment ◽  
Collective Efficacy ◽  
Cross Sectional Study ◽  
Socioeconomic Conditions ◽  
Sectional Study ◽  
Cross Sectional ◽  
Neighborhood Collective Efficacy ◽  
The Us ◽  
Nationally Representative

Objectives: The development and severity of attention deficit hyperactivity disorder (ADHD) has been linked to a number of psychosocial risk factors. Research has shown that the amount of social capital in a community influences the physical and mental health of community members. We assessed the independent role of perceived neighborhood context, including physical and socioeconomic characteristics, and collective efficacy, a form of social capital, on ADHD prevalence. Methods: Cross-sectional study utilizing the 2007 National Survey of Children’s Health, a nationally representative dataset. The population of interest was children between the ages of four and seventeen living in randomly selected households. Multiple logistic regression models were used to assess the association between indices of perceived neighborhood socioeconomic conditions, built environment, and collective efficacy (study exposures) on risk of ADHD (outcome), controlling for pertinent individual and family risk factors.Results: 9.8 percent of children in the US (ages 4‐17) had ADHD as reported by their caregiver. In multivariate analysis, white race, male gender, increased geographic mobility, exposure to household smoke, exposure to > 2 hours/day TV, and maternal mental illness increased the odds of ADHD, while a two‐parent household reduced the odds. The highest level of perceived neighborhood collective efficacy was associated with reduced risk of ADHD compared to lower levels of perceived collective efficacy (adjusted OR: 0.785; 95% CI: 0.650-0.946; p=.011). Perceived neighborhood socioeconomic conditions and built environment were not associated with ADHD risk.Results: Nine percent of children in the US (ages 4-17 ) had ADHD as reported by their caregiver. Univariately, all 3 neighborhood characteristics were associated with risk of ADHD (p-value =.01, .04, and .0002 for socioeconomic conditions, built environment, and collective efficacy, respectively). After accounting for well-established risk factors for ADHD, perceived neighborhood socioeconomic conditions and built environment were no longer associated with ADHD, while collective efficacy remained significant (p=.0002).  Lower level of perceived neighborhood collective efficacy was associated with increased risk of ADHD (OR: 1.7; 95\% CI: 1.3-2.2, comparing the lowest with the highest level).Conclusions: Our study suggests that perceived neighborhood collective efficacy may buffer the impact of individual-and family-level risk factors for ADHD in children.

scholarly journals Association between the number of prosthetic crowns and periodontitis: a cross-sectional study

2021 ◽  
Author(s):  
Yun-Jeong Kim ◽  
Jae-Young Lee ◽  
Young Ku ◽  
Hyun-Jae Cho
Keyword(s):  
Odds Ratio ◽  
Cross Sectional Study ◽  
Demographic Variables ◽  
Nutrition Examination Survey ◽  
Regression Analyses ◽  
Sectional Study ◽  
Multivariate Logistic Regression ◽  
Cross Sectional ◽  
Health And Nutrition ◽  
Health Related

Abstract BackgroundAlthough the presence of prosthetic restorations has been associated with plaque accumulation, gingivitis, and periodontitis, there is a lack of large epidemiological investigations providing credible evidence on the association of prosthetic crowns with periodontitis. The purpose of the study was to analyze the association between the number of prosthetic crowns and the presence of periodontitis.MethodsThis study was based on the Seventh Korea National Health and Nutrition Examination Survey (2016-2018). A total of 12,689 participants over the age of 19 years were surveyed. Multivariate logistic regression analyses were used to identify the association between the number of prosthetic crowns and periodontitis after adjusting for potential confounders, including demographic variables, socio-economic characteristics, oral health-related variables, and oral and systemic clinical variables. ResultsThe odds ratio of periodontitis showed statistically significant differences in the anterior and posterior regions, and the prevalence of periodontal disease increased as the number of crown prostheses increased. Participants with 6–10 and 11 prosthetic crowns had 1.24 and 1.28 times higher prevalence of periodontitis, respectively, than patients with no prosthetic crown.ConclusionsThe results of this study show that the number of prosthetic crowns present in adults is related to the prevalence of periodontitis.

Dietary sodium:potassium ratio and CVD risk factors among Japanese adults: a retrospective cross-sectional study of pooled data from the National Health and Nutrition Survey, 2003–2017

2020 ◽  
Vol 125 (1) ◽  
pp. 79-91
Author(s):  
Emiko Okada ◽  
Chika Okada ◽  
Mai Matsumoto ◽  
Aya Fujiwara ◽  
Hidemi Takimoto
Keyword(s):  
Risk Factors ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Cvd Risk Factors ◽  
Nutrition Survey ◽  
Cvd Risk ◽  
Cross Sectional ◽  
Health And Nutrition ◽  
Cholesterol Levels ◽  
Japanese Adults

AbstractFew studies have reported associations between the Na:K ratio and risk factors related to CVD among the general population in Asian countries. This study aimed to investigate the dietary Na:K ratio association with CVD risk factors among Japanese adults. This retrospective cross-sectional study included 48 800 Japanese participants (19 386 men and 29 414 women) aged ≥20 years, registered in the 2003–2017 National Health and Nutrition Survey. Multivariate OR and 95 % CI for risk of hypertension, high glycated HbA1c levels, hypercholesterolaemia, low serum levels of HDL-cholesterol and high non-HDL-cholesterol levels according to the Na:K ratio were estimated using logistic regression models. Dietary Na:K ratio decreased for both men and women from 2003 to 2017. Higher Na:K ratio and higher hypertension prevalence were observed (multivariate OR (fifth v. first quintiles) 1·27, 95 % CI 1·15, 1·40; Pfor trend < 0·001 for men and 1·12, 95 % CI 1·01, 1·23; Pfor trend = 0·007 for women). Higher Na:K ratio was associated with higher prevalence of high HbA1c levels in men (multivariate OR 1·56, 95 % CI 1·24, 1·96). Prevalence of low HDL-cholesterol levels was increased with higher Na:K ratio (Pfor trend =0·002 for men and <0·001 for women). No significant associations were found between Na:K ratio and hypercholesterolaemia in men or high non-HDL-cholesterol levels in both men and women. Our findings suggest that dietary Na:K ratio is associated with several CVD risk factors among Japanese adults.

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