scholarly journals A Dead Case Report From Brain Abscess Caused by Nocardia Farcinica

Author(s):  
Jiangqin Song ◽  
Lian Dong ◽  
Yan Ding ◽  
Junyang Zhou

Abstract Background: Brain abscess due to the Nocardia genus is rarely reported and it is usually found in immunocompromised patients. Treatment of Nocardia brain abscess is troublesome and requires consideration of the severity of the underlying systemic disease. The difficulties in identifying the bacterium and the frequent delay in initiating adequate therapy often influence the prognosis of patients.Case presentation: Here, we report a rare case of brain abscess caused by Nocardia farcinica. The patient’s medical history was complicated, he was hospitalized for several times, but no pathogens were found. At last, bacterial was found in culture of brain abscess puncture fluid, the colony was identified as Nocardia farcinica by mass spectrometry. Targeted antibiotic treatment was implemented, brain abscess tended to alleviate, but the patient eventually developed fungal pneumonia and died of acute respiratory distress syndrome (ARDS). Conclusion: brain abscess caused by Nocardia farcinica can be appear in non-immunocompromised individuals. Early diagnosis, reasonable surgical intervention, and targeted antibiotic treatment are critical for Nocardia brain abscess treatment. In the treatment of Nocardia brain abscess, we should pay attention to the changes of patients' immunity and avoid infection with other pathogens, especially fungi.

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Jiangqin Song ◽  
Lian Dong ◽  
Yan Ding ◽  
Junyang Zhou

Abstract Background Brain abscess due to the Nocardia genus is rarely reported and it is usually found in immunocompromised patients. Treatment of Nocardia brain abscess is troublesome and requires consideration of the severity of the underlying systemic disease. The difficulties in identifying the bacterium and the frequent delay in initiating adequate therapy often influence the prognosis of patients. Case presentation Here, we report a rare case of brain abscess caused by Nocardia farcinica. The patient’s medical history was complicated: he was hospitalized several times, but no pathogens were found. At last, bacteria were found in the culture of brain abscess puncture fluid; the colony was identified as Nocardia farcinica by mass spectrometry. Targeted antibiotic treatment was implemented, brain abscess tended to alleviate, but the patient eventually developed fungal pneumonia and died of acute respiratory distress syndrome (ARDS). Conclusion Brain abscess caused by Nocardia farcinica can appear in non-immunocompromised individuals. Early diagnosis, reasonable surgical intervention, and targeted antibiotic treatment are critical for Nocardia brain abscess treatment. In the treatment of Nocardia brain abscess, attention should paid be to the changes in patients’ immunity and infection with other pathogens, especially fungi, avoided.


2021 ◽  
Author(s):  
Jiangqin Song ◽  
Lian Dong ◽  
Yan Ding ◽  
Weifang Zhu ◽  
Junyang Zhou

Abstract Background Brain abscess due to the Nocardia genus is rarely reported that usually found in immunocompromised patients. Treatment of Nocardia brain abscess is troublesome and requires consideration of the severity of the underlying systemic disease, the difficulties in identifying the bacterium and the frequent delay in initiating adequate therapy. Case Presentation Here, we report a rare case of brain abscess caused by Nocardia farcinica. The patient’s medical history was complicated, bacterial was found in culture of brain abscess puncture fluid, the colony was identified as Nocardia farcinica by mass spectrometry. Targeted antibiotic treatment was implemented, brain abscess tended to alleviate, but the patient eventually developed fungal pneumonia and died of acute respiratory distress syndrome (ARDS).Conclusion Early diagnosis, reasonable surgical intervention, and targeted antibiotic treatment are critical for Nocardia brain abscess treatment. Any delay in diagnosis and appropriate therapy can have adverseconsequences.


2021 ◽  
pp. 442-444
Author(s):  
Aarti Mahesh Khare ◽  
Sachin Tukaram Nemane ◽  
Prashant Shridhar Javade ◽  
Yogesh Pralhad Narkhede ◽  
Punita A. Parti

Mucormycosis is an opportunistic fungal infection caused by omnipresent fungi called Mucorales of class Phycomycetes. It mainly occurs in immunocompromised patients, and only early diagnosis with medical and surgical intervention remains the gold standard in managing it. Here, we present the case of a patient contracted with mucormycosis post his COVID-19 infection involving the rhino-orbito-maxillary area. The patient presented to our hospital with dental pain a month after his discharge. Since the mucormycosis cases were at a peak in this period, our team of doctors did a thorough examination of the patient, which revealed dental and ophthalmologic abnormalities. No clinical necrotic eschar in the palatine or nasal cavity was diagnosed, but magnetic resonance imaging (MRI) revealed a typical COVID-19 mucormycosis infection. Accordingly, prompt treatment with systemic amphotericin B was started. However, as the patient declined surgical intervention, we feared the worst outcome, which to our surprise showed no adverse progression.


2017 ◽  
Vol 5 ◽  
Author(s):  
Stephen J. Goldie ◽  
Shaun Parsons ◽  
Hana Menezes ◽  
Andrew Ives ◽  
Heather Cleland

Abstract Background Patients presenting with large surface area burns are common in our practice; however, patients with a secondary large burn on pre-existing burn scars and grafts are rare and not reported. Case presentation We report on an unusual case of a patient sustaining a secondary large burn to areas previously injured by a burn from a different mechanism. We discuss the potential implications when managing a case like this and suggest potential biological reasons why the skin may behave differently. Our patient was a 33-year-old man who presented with a 5% TBSA burn on skin scarred by a previous 40% total body surface area (TBSA) burn and skin grafts. Initially assessed as superficial partial thickness in depth, the wounds were treated conservatively with dressings; however, they failed to heal and became infected requiring surgical management. Conclusions Burns sustained in areas of previous burn scars and grafts may behave differently to normal patterns of healing, requiring more aggressive management and surgical intervention at an early stage.


2021 ◽  
Vol 07 (02) ◽  
pp. e66-e68
Author(s):  
Jignesh A. Gandhi ◽  
Pravin Shinde ◽  
Bhavika Kothari ◽  
Marina Kharkongor

Abstract Introduction Peptic ulcer usually presents to the emergency in the form of an acute abdomen, which is usually diagnosed easily either clinically or radiologically. Although its incidence has decreased with the introduction on proton pump inhibitors it is still one of the most common emergencies encountered by a surgeon. Case Presentation A 60-year-old woman complained of epigastric swelling for 6 months which gradually increased and became irreducible over the last 2 months. The patient also complained of pain associated with vomiting. Radiological investigations revealed a epigastric hernia with omentum and stomach as content along with fluid collection in the right perihepatic region, with tiny air foci. The patient was explored for the same. Discussion Perforated peptic ulcer is a serious complication and carries high risk of morbidity and mortality. Early diagnosis with immediate resuscitation and surgical intervention is essential to improve outcomes. This is a rare case of perforated gastric ulcer which was masked under the complicated ventral hernia.


2021 ◽  
Vol 14 (9) ◽  
Author(s):  
Liyan Zhou ◽  
Weijuan Qin ◽  
Zhengyi Liang ◽  
Huanhuan Wei ◽  
Xiaoning Wu

Introduction: The incidence of infection by Ralstonia is increasing. Several reports describing infection by these bacteria in immunocompromised patients have been published. In this study, we reported a case of Ralstonia (R.) pickettii infection in a patient with normal immunity. Case Presentation: A woman presented with fever after thyroid surgery. We identified R. pickettii in her blood culture using 16S rRNA gene sequencing. The patient’s condition improved clinically upon treatment with levofloxacin. Conclusions: Our report highlights the potential of Ralstonia to cause sepsis in patients with normal immunity and emphasizes the importance of blood culture testing when a hospitalized patient has an unexplained high fever.


2015 ◽  
Vol 01 (01) ◽  
pp. 002-004
Author(s):  
Karan Hantodkar ◽  
Mahesh Mohite ◽  
Pankaj Deshpande

AbstractCystinosis is a systemic disease caused by defect in metabolism of Cystine. It typically presents as Fanconi syndrome with metabolic acidosis, polyuria, failure to thrive, glucosuria, phophaturia and aminoaciduria. Our patient did not display metabolic acidosis at presentation and had features suggesting Bartter's syndrome.


2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Khuram Khan ◽  
Saqib Saeed ◽  
Haytham Maria ◽  
Mohammed Sbeih ◽  
Farhana Iqbal ◽  
...  

Introduction. Duodenal diverticulum is a rare disease that can be easily missed. The incidence of duodenal diverticulum diagnosed by upper GI study is approximately 5%. Autopsy results show that 22% of the population have duodenum diverticulum. Most patients with duodenal diverticulum are asymptomatic. However, complications like inflammation, perforation with retroperitoneal abscess, sepsis, pancreatitis, bile duct obstruction, and bleeding can occur. Approximately 162 cases of perforated duodenal diverticulum have been reported in the literature. Case Presentation. We present a rare case of an 82-year-old female with perforation of a duodenal diverticulum caused by small bowel obstruction; in addition to this, there was a synchronous colonic tumor. Conclusion. Diagnosis and management of this rare disorder are controversial. Nonoperative management is advocated in some cases. Some of the cases require early aggressive surgical intervention. The mortality rate remains approximately 45% in all these patients.


2021 ◽  
pp. 20-24
Author(s):  
D. Balasa ◽  
A. Tunas ◽  
A.V. Stan

Introduction: Cerebral infections (frontoparietal extradural and subdural empyema) following a dental abscess and multiple sinusitis is a rare and potentially devastating entity even in the era of modern diagnosis and treatment. Case presentation: We present a patient with parietal epidural and subdural empyema and intracerebral frontal abscess, sinusitis and dental abscess, chronic consumer of alcohol and with neglected diabetes mellitus. He was initially diagnosed with encapsulated hematoma and sinusitis. The pus obtained at the intervention was certified by our laboratory as sterile with the consequent difficulty in antibiotic treatment and who induced a longer antibiotic treatment, a second surgical intervention for an encapsulated frontal abscess, a longer hospitalisation and favoured contamination with Covid 19. Despite these, the patient had a finally good evolution. Conclusions: A frontoparietal extradural and subdural empyema and an intracerebral frontal abscess produced by a dental abscess and sinusitis is a rare and potentially lethal complication. The multidisciplinary approach between radiologist, neurosurgeon, otolaryngologist, dentist, microbiologists is mandatory for a proper diagnosis and treatment of these pathologies.


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