scholarly journals Ten- Year-Old Female with Dieulafoy Lesion Treated with Therapeutic Endoscopy And Literature Review

2020 ◽  
Author(s):  
Ying Chen ◽  
Mei Sun ◽  
Xu Teng
Keyword(s):  
Differential Diagnosis ◽  
Clinical Manifestations ◽  
Therapeutic Endoscopy ◽  
Abdominal Ct ◽  
Vascular Abnormality ◽  
Case Presentation ◽  
Appropriate Treatment ◽  
Massive Hematemesis ◽  
Dieulafoy Lesion

Abstract Background There are many causes of sudden gastrointestinal bleeding in children, Dieulafoy lesion is very rare. This vascular abnormality can be fatal without appropriate treatment.Case presentation Retrospective analysis of the clinical manifestations, endoscopic features and treatment of a Chinese child with Dieulafoy lesion and review relevant literatures.Result A 10-year-old girl was admitted to hospital with sudden massive hematemesis and melena. Abdominal CT revealed suspected submucosal bleeding in the stomach. Finally the disease was diagnosed due to the typical manifestations with endoscopy. Meanwhile, we used electrocoagulation and hemoclips to hemostasis under endoscopy. No recurrence of hematemesis identified during the 4-weeks follow-up.Conclusion Dieulafoy lesion in children is rare cause of sudden gastrointestinal hemorrhage. But differential diagnosis cannot ignore it. Endoscope is the optimize choice for diagnosis and treatment.

scholarly journals Small intestine duplication cyst with recurrent hematochezia: a case report and literature review

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zhicheng Zhang ◽  
Xiaowei Huang ◽  
Qian Chen ◽  
Demin Li ◽  
Qi Zhou ◽  
...  
Keyword(s):  
Small Intestine ◽  
Case Report ◽  
Literature Review ◽  
Ct Scan ◽  
Duplication Cyst ◽  
Abdominal Ct ◽  
Case Presentation ◽  
Abdominal Ct Scan ◽  
Capsule Endoscopes

Abstract Background Small intestine duplication cysts (SIDCs) are rare congenital anatomical abnormalities of the digestive tract and a rare cause of hematochezia. Case presentation We describe an adult female presented with recurrent hematochezia. The routine gastric endoscope and colonic endoscope showed no positive findings. Abdominal CT scan indicated intussusception due to the "doughnut" sign, but the patient had no typical symptoms. Two subsequent capsule endoscopes revealed a protruding lesion with bleeding in the distal ileum. Surgical resection was performed and revealed a case of SIDC measuring 6 * 2 cm located inside the ileum cavity. The patient remained symptom-free throughout a 7-year follow-up period. Conclusion SIDCs located inside the enteric cavity can easily be misdiagnosed as intussusception by routine radiologic examinations.

scholarly journals Identification of NR0B1 Gene Mutation and Analysis of Bone Damages and Drug Treatment Effect in a Big Family With X-linked Adrenal Hypoplasia Congenita: a Case Report

2021 ◽  
Author(s):  
XIAOHUI TAO ◽  
LI LIU ◽  
XIAOYUN LIN ◽  
TIAN XU ◽  
HUA YUE ◽  
...  
Keyword(s):  
Mass Density ◽  
Hypogonadotropic Hypogonadism ◽  
Clinical Manifestations ◽  
Osteonecrosis Of The Jaw ◽  
Bone Mass Density ◽  
Insertion Mutation ◽  
Case Presentation ◽  
Skeletal Complications ◽  
Adrenal Hypoplasia

Abstract Background: X-linked congenital adrenocortical hypoplasia (XL-AHC) is a rare disorder, which is characterized by primary adrenal insufficiency and hypogonadotropic hypogonadism. However, the skeletal complications caused by the disease were rarely reported, not to mention the treatment.Case presentation: The patient from a big family with XL-AHC was identified carrying a homozygous insertion mutation（p.Thr193GlyfsX13）in DAX-1 gene. The diagnosis of secondary osteoporosis was made after imaging, laboratory and bone mass density examinations. However, he showed a suboptimal response to bisphosphonates during 2 years of follow-up, even suffered from atypical femoral fracture (AFF). Now it had been replaced by menatetrenone, bone healing was satisfactory. Conclusions: We harbored the idea that clinicians should not only focus on typical clinical manifestations of XL-AHC, but also pay attention to the skeletal complications in clinical practice. Conventional anti-osteoporosis drugs may cause side effects such as AFF and osteonecrosis of the jaw (ONJ), which was rare in general osteoporosis patients. In other words, anabolic agent may be a better choice.

scholarly journals Infection-provoked reversible posterior leukoencephalopathy syndrome in an adult with nephrotic syndrome: a case report

BMC Neurology ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Kuan-Ying Li ◽  
Ching-Fang Chien ◽  
Chin-Ling Tsai ◽  
Huang-Chi Chen ◽  
Meng-Ni Wu ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Altered Mental Status ◽  
Reversible Posterior Leukoencephalopathy Syndrome ◽  
Asian Woman ◽  
Case Presentation ◽  
Reversible Posterior Leukoencephalopathy ◽  
Posterior Leukoencephalopathy ◽  
Appropriate Treatment ◽  
Visual Disturbances

Abstract Background Reversible posterior leukoencephalopathy syndrome (RPLS) is a rare and heterogeneous clinico-neuroradiological syndrome characterized by headache, altered mental status, seizures, and visual disturbances. Hypertension and immunosuppression are two of the main factors that predispose an individual to RPLS. However, RPLS can develop when no major risk factors are present. RPLS has been reported in pediatric nephrotic patients, but rarely in adults. Case presentation A 42-year-old Asian woman with nephrotic syndrome presented with seizures, headaches, and nausea. Her blood pressure was controlled, and no immunosuppressants had been prescribed. All symptoms and tests indicated RPLS following infection with pneumonia, which was successfully treated by immediate administration antibiotic and anti-epileptic medications. Seizures did not recur during a 2-year follow-up period. Conclusions When patients with nephrotic syndrome have an infection, RPLS symptoms should be investigated thoroughly. With early diagnosis and appropriate treatment of RPLS, morbidity and mortality can be prevented.

scholarly journals A Solitary Giant Neurofibroma of Inguinal Region—A Case Report

2020 ◽  
Author(s):  
Haiying Zhou ◽  
Hui Lu
Keyword(s):  
Tumor Resection ◽  
Clinical Manifestations ◽  
Inguinal Region ◽  
Case Presentation ◽  
Neurogenic Tumors ◽  
Long Time ◽  
Giant Neurofibroma ◽  
History Of ◽  
Recurrence Tendency

Abstract Background:Neurofibroma is a rare nerve sheath tumorofneuroectodermal origin, especially the huge and isolated neurofibroma located in the inguinal region. To our knowledge, no such case has previously been reported.Case presentation:We report a case of 34-year-old male patient with a 4-year history of progressive enlargement of the medial root mass in his left thigh with sitting and standing disorders along with pain. The tumor was completely removed by operation, and pathological diagnosisshowed neurofibroma. There was no obvious neurologic defect after surgery, and no recurrence tendency was found in the follow-up of 2years.Conclusions:For a large solitary mass with slow growth and no malignant clinical manifestations for a long time, clinicians can not rule out the hypothetical diagnosis of neurofibroma, even though its growth site is very rare, such as this case of a huge tumor located in the groin. For neurogenic tumors, early operation should be performed, and the prognosis of patients after tumor resection isexcellent.

scholarly journals A symptomatic cyamella in the popliteus tendon causing snapping knee: a case report and literature review

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Shouwen Su ◽  
Yunxiang Lu ◽  
Yuxian Chen ◽  
Zhiyong Li
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Literature Review ◽  
Popliteus Tendon ◽  
Case Presentation ◽  
Sesamoid Bones ◽  
Snapping Knee ◽  
Popliteus Muscle

Abstract Background Cyamella,the sesamoid bones of the popliteus muscle, are rare in humans. Snapping knee is an uncommon problem which can be difficult to diagnose. Case presentation In this case, we report a 24-year-old male with snapping knee caused by symptomatic cyamella in the popliteus tendon. A large cyamella was identified upon surgery and was removed. Postoperatively, the patient had immediate relief of preoperative symptoms, and there were no signs of recurrence after 1 years of follow-up. Conclusions Although not previously suggested, symptomatic cyamella in the popliteus tendon should be considered as part of the differential diagnosis of the snapping knee.

scholarly journals Anterior orbital leiomyoma originating from the supraorbital neurovascular bundle

2017 ◽  
Vol 5 ◽  
pp. 2050313X1774099
Author(s):  
Selam Yekta Sendul ◽  
Cemile Ucgul Atilgan ◽  
Fevziye Kabukcuoglu ◽  
Semra Tiryaki Demir ◽  
Dilek Guven
Keyword(s):  
Differential Diagnosis ◽  
Dermoid Cyst ◽  
Female Patient ◽  
Excisional Biopsy ◽  
Young Female ◽  
Neurovascular Bundle ◽  
Upper Eyelid ◽  
Case Presentation ◽  
Orbital Tumour

Purpose: To present a young female patient with left anterior orbital leiomyoma that originates from the supraorbital neurovascular bundle. Case presentation: A 41-year-old female patient was admitted to our clinic with a complaint of swelling of the left upper eyelid. Based on the ophthalmological and imaging assessments, the excisional biopsy with the preliminary diagnosis of dermoid cyst was planned. The histopathological and immunohistochemical examinations of excised sample revealed surprisingly that the tumour was a leiomyoma. No recurrence was detected in the patient’s follow-up. Conclusion: Although it is rare, orbital leiomyoma should be considered in the differential diagnosis of patients with orbital tumour.

Solitary plasmacytoma of the index finger

2014 ◽  
Vol 67 (9) ◽  
pp. 828-831
Author(s):  
Yahya Daneshbod ◽  
Pooria Ali Nowshadi ◽  
Shahrzad Negahban ◽  
Azita Aledavood ◽  
Mani Ramzi ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Index Finger ◽  
Relevant Literature ◽  
Disease Spread ◽  
Solitary Plasmacytoma ◽  
Regional Lymph Nodes ◽  
Case Presentation ◽  
Distal Extremity ◽  
Systemic Involvement

IntroductionSolitary osseous plasmacytoma rarely involves the distal extremities. We report a case and provide a brief review of the relevant literature.Case presentationWe report a 64-year-old man who presented with swelling, mild pain and a deformed right index finger. The workup led to the diagnosis of solitary osseous plasmacytoma and the patient eventually required amputation of his finger. With clinical follow-up, the disease spread to regional lymph nodes and subsequently the patient developed systemic involvement and received chemotherapy.ConclusionsSolitary osseous plasmacytoma should be considered in the differential diagnosis of distal extremity neoplasms.

scholarly journals Tubal choriocarcinoma presented as ruptured ectopic pregnancy: a case report and review of the literature

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Shengjie Xu ◽  
Xiaohong Song ◽  
Chengjuan Jin ◽  
Yanli Li
Keyword(s):  
Ectopic Pregnancy ◽  
Tumor Metastasis ◽  
Actinomycin D ◽  
Clinical Manifestations ◽  
Case Presentation ◽  
Delayed Treatment ◽  
Missed Diagnosis ◽  
Β Hcg ◽  
Histopathological Results

Abstract Background Tubal choriocarcinoma is an extremely rare but highly malignant trophoblastic tumor, which may be either gestational or non-gestational in origin. Due to atypical clinical manifestations and symptoms similar to ectopic pregnancy, it is easily to be confused with ectopic pregnancy. In addition, inadequate understanding of this rare disease by clinicians often leads to misdiagnosis or missed diagnosis, which in turn results in delayed treatment or even tumor metastasis. Case presentation This report summarized a case of a woman who was finally diagnosed as tubal choriocarcinoma through the follow-up of serum β hCG levels and histopathological results after undergoing salpingectomy for being misdiagnosed as ectopic pregnancy. Five courses of adjuvant chemotherapy (5-fluorouracil, actinomycin-D, vinorelbine regime) have been administered to the patient in the prevention of any recurrences. During 1-year follow-up, the patient was asymptomatic and presented no evidence of recurrence. Conclusions Tubal choriocarcinoma is easily to be confused with ectopic pregnancy. By analyzing this case and previous related cases, we aimed to provide references for clinicians in the diagnosis and treatment of tubal choriocarcinoma.

scholarly journals Malignant Transformation of Liver Cysts Into Cholangiocarcinoma During Follow-up: Potential Dangers of Liver Cysts

2021 ◽  
Author(s):  
Fu-sheng Liu ◽  
Ke-lu Li ◽  
Yue-ming He ◽  
Zhong-lin Zhang ◽  
Yu-feng Yuan ◽  
...  
Keyword(s):  
Cyst Wall ◽  
Clinical Manifestations ◽  
Liver Cyst ◽  
Common Disease ◽  
Case Presentation ◽  
Liver Cysts ◽  
Cystic Tumors ◽  
Laboratory Examinations ◽  
Malignant Changes

Abstract Background: The liver cyst is a common disease in hepatobiliary surgery. Most patients have no apparent symptoms and are usually diagnosed accidentally during imaging examinations. The vast majority of patients with liver cysts follow a benign course, with very few serious complications and rare reports of malignant changes. Case Presentation: We present two cases of liver cysts that evolved into intrahepatic tumors during the follow-up process. The first patient had undergone a fenestration and drainage operation for the liver cyst, and the cancer was found at the cyst’s position in the third year after the procedure. Microscopically, bile duct cells formed the cyst wall. Tumor cells can be seen on the cyst wall and its surroundings to form adenoid structures of different sizes, shapes, and irregular arrangements, some of which are arranged in clusters. The second patient was regularly rechecked after discovering liver cysts, and a new mass appeared very close to the cyst. The clinical manifestations and laboratory examinations of the two patients lacked specificity, the preoperative diagnosis was unclear, and the postoperative pathology confirmed cholangiocarcinoma.Conclusions: Our cases indicate that liver cysts may lead to the occurrence of malignant intrahepatic cholangiocarcinoma. Therefore, follow-up of particular liver cysts is necessary, and the differential diagnosis of the intrahepatic cystic tumors needs to include cholangiocarcinoma.

scholarly journals Congenital Syphilis in Neonate: A Single Center Study for 10 Years

2021 ◽  
Vol 25 (3) ◽  
pp. 204-210
Author(s):  
Narae Lee ◽  
Mun Hui Jeong ◽  
Seong Hee Jeong ◽  
Mi-Hye Bae ◽  
Young Mi Han ◽  
...  
Keyword(s):  
Congenital Syphilis ◽  
Clinical Manifestations ◽  
Single Center ◽  
Antibody Absorption ◽  
Appropriate Treatment ◽  
Single Center Study ◽  
The Republic ◽  
Bone Abnormalities ◽  
Center Study

Purpose: Syphilis infections are becoming more prevalent in the Republic of Korea, and inadequately treated syphilis can lead to congenital syphilis (CS) in newborns. This study aimed to analyze the clinical manifestations of syphilis in mothers and newborns and to make suggestions to improve disease prognosis. Methods: This single-center study was performed between August 2009 and August 2019 and included 29 newborns with CS. We retrospectively evaluated the clinical features, rapid plasma reagin (RPR) card test, fluorescent treponemal antibody absorption test (FTA-ABS), morbidity, and treatment regimen of all the syphilis-affected mothers and their newborns. Results: At the time of delivery, mean maternal age was 29.0±6.1 years old, and newborn gestational age was 38.0 weeks. In cases when syphilis was confirmed during the second and third trimesters of pregnancy, the newborn with CS had morbidity (p=0.004). The mean RPR titer was related to morbidity (p= 0.036). Positive results of FTA-ABS IgM (p<0.001) and pleocytosis in the cerebrospinal fluid (CSF) (p= 0.020) also increase morbidity. The most common symptoms were desquamation and skin rash, followed by hepatomegaly, neurodevelopmental disability, and bone abnormalities. The highest number of CS cases per 1,000 live births in this hospital was in 2014. Conclusion: CS is a preventable and treatable disease if physicians detect symptoms and provide appropriate treatment through RPR examinations during every trimester. General practitioners should be widely trained on various aspects including early detection, formal treatment, and regular follow-up. Additionally, medical services should be provided for the entire childbearing population regardless of the socioeconomic status.

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