In-Utero Exposure to Indoor Air Pollution or Tobacco Smoke and Cognitive Development in a South African Birth Cohort Study

2022 ◽  
Author(s):  
Grace M. Christensen ◽  
Junyu Chen ◽  
Aneesa Vanker ◽  
Nastassja Koen ◽  
Meaghan J. Jones ◽  
...  
Author(s):  
Aneesa Vanker ◽  
Whitney Barnett ◽  
Polite M. Nduru ◽  
Kirsty Brittain ◽  
Robert P. Gie ◽  
...  

2016 ◽  
Vol 2016 (1) ◽  
Author(s):  
Rajitha WICKREMESINGHE* ◽  
Sumal nandasena ◽  
Anuradhini Kasturiratne ◽  
Arunasalem Pathmeswaran ◽  
Meghan Tipre ◽  
...  

2015 ◽  
Vol 536 ◽  
pp. 362-367 ◽  
Author(s):  
Aneesa Vanker ◽  
Whitney Barnett ◽  
Polite M. Nduru ◽  
Robert P. Gie ◽  
Peter D. Sly ◽  
...  

2019 ◽  
Vol 5 (1) ◽  
pp. 00052-2018 ◽  
Author(s):  
Aneesa Vanker ◽  
Polite M. Nduru ◽  
Whitney Barnett ◽  
Felix S. Dube ◽  
Peter D. Sly ◽  
...  

Indoor air pollution (IAP) or environmental tobacco smoke (ETS) exposure may influence nasopharyngeal carriage of bacterial species and development of lower respiratory tract infection (LRTI). The aim of this study was to longitudinally investigate the impact of antenatal or postnatal IAP/ETS exposure on nasopharyngeal bacteria in mothers and infants.A South African cohort study followed mother–infant pairs from birth through the first year. Nasopharyngeal swabs were taken at birth, 6 and 12 months for bacterial culture. Multivariable and multivariate Poisson regression investigated associations between nasopharyngeal bacterial species and IAP/ETS. IAP exposures (particulate matter, carbon monoxide, nitrogen dioxide, volatile organic compounds) were measured at home visits. ETS exposure was measured through maternal and infant urine cotinine. Infants received the 13-valent pneumococcal andHaemophilus influenzaeB conjugate vaccines.There were 881 maternal and 2605 infant nasopharyngeal swabs. Antenatal ETS exposure was associated withStreptococcus pneumoniaecarriage in mothers (adjusted risk ratio (aRR) 1.73 (95% CI 1.03–2.92)) while postnatal ETS exposure was associated with carriage in infants (aRR 1.14 (95% CI 1.00–1.30)) Postnatal particulate matter exposure was associated with the nasopharyngeal carriage ofH. influenzae(aRR 1.68 (95% CI 1.10– 2.57)) orMoraxella catarrhalis(aRR 1.42 (95% CI 1.03–1.97)) in infants.Early-life environmental exposures are associated with an increased prevalence of specific nasopharyngeal bacteria during infancy, which may predispose to LRTI.


2016 ◽  
Vol 2016 (1) ◽  
Author(s):  
Bram Janssen* ◽  
Nelly Saenen ◽  
Harry Roels ◽  
Narjes Madhloum ◽  
Wilfried Gyselaers ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document