scholarly journals A 3D-Printed Multi-Chamber Device Allows Culturing Cells On Buckypapers Coated With PAMAM Dendrimer And Obtain Innovative Materials For Biomedical Applications

2019 ◽  
Vol Volume 14 ◽  
pp. 9295-9306 ◽  
Author(s):  
Alessandro Paolini ◽  
Giulia Battafarano ◽  
Valentina D'Oria ◽  
Francesco Mura ◽  
Simona Sennato ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Pamam Dendrimer ◽  
Innovative Materials ◽  
3D Printed

scholarly journals MicroRNAs delivery into human cells grown on 3D-printed PLA scaffolds coated with a novel fluorescent PAMAM dendrimer for biomedical applications

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Alessandro Paolini ◽  
Luca Leoni ◽  
Ilaria Giannicchi ◽  
Zeinab Abbaszadeh ◽  
Valentina D’Oria ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Pamam Dendrimer ◽  
Human Cells ◽  
3D Printed

Experimental investigations into abrasive flow machining (AFM) of 3D printed ABS and PLA parts

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Nitin Dixit ◽  
Varun Sharma ◽  
Pradeep Kumar
Keyword(s):  
Surface Roughness ◽  
Biomedical Applications ◽  
Fused Deposition Modeling ◽  
Experimental Investigations ◽  
Future Research ◽  
Content Type ◽  
Abrasive Flow Machining ◽  
Fused Deposition ◽  
Cylindrical Parts ◽  
3D Printed

Purpose The surface roughness of additively manufactured parts is usually found to be high. This limits their use in industrial and biomedical applications. Therefore, these parts required post-processing to improve their surface quality. The purpose of this study is to finish three-dimensional (3D) printed acrylonitrile butadiene styrene (ABS) and polylactic acid (PLA) parts using abrasive flow machining (AFM). Design/methodology/approach A hydrogel-based abrasive media has been developed to finish 3D printed parts. The developed abrasive media has been characterized for its rheology and thermal stability using sweep tests, thermogravimetric analysis (TGA) and differential thermal analysis (DTA). The ABS and PLA cylindrical parts have been prepared using fused deposition modeling (FDM) and finished using AFM. The experiments were designed using Taguchi (L9 OA) method. The effect of process parameters such as extrusion pressure (EP), layer thickness (LT) and abrasive concentration (AC) was investigated on the amount of material removed (MR) and percentage improvement in surface roughness (%ΔRa). Findings The developed abrasive media was found to be effective for finishing FDM printed parts using AFM. The microscope images of unfinished and finished showed a significant improvement in surface topography of additively manufactures parts after AFM. The results reveal that AC is the most significant parameter during the finishing of ABS parts. However, EP and AC are the most significant parameters for MR and %ΔRa, respectively, during the finishing of PLA parts. Practical implications The FDM technology has applications in the biomedical, electronics, aeronautics and defense sectors. PLA has good biodegradable and biocompatible properties, so widely used in biomedical applications. The ventilator splitters fabricated using FDM have a profile similar to the shape used in the present study. Research limitations/implications The present study is focused on finishing FDM printed cylindrical parts using AFM. Future research may be done on the AFM of complex shapes and freeform surfaces printed using different additive manufacturing (AM) techniques. Originality/value An abrasive media consists of xanthan gum, locust bean gum and fumed silica has been developed and characterized. An experimental study has been performed by combining printing parameters of FDM and finishing parameters of AFM. A comparative analysis in MR and %ΔRa has been reported between 3D printed ABS and PLA parts.

3D‐Printed Micromotors for Biomedical Applications

2020 ◽  
Vol 5 (11) ◽  
pp. 2000435
Author(s):  
Junhong Ye ◽  
Daniela A. Wilson ◽  
Yingfeng Tu ◽  
Fei Peng
Keyword(s):  
Biomedical Applications ◽  
3D Printed

scholarly journals Heat Treatment Effect on Mechanical Properties of 3D Printed Polymers

2019 ◽  
Vol 264 ◽  
pp. 02001 ◽  
Author(s):  
Eduardo de Avila ◽  
Jaeseok Eo ◽  
Jihye Kim ◽  
Namsoo P. Kim
Keyword(s):  
Mechanical Properties ◽  
Heat Treatment ◽  
Treatment Effect ◽  
Biomedical Applications ◽  
Treatment Process ◽  
Heat Treatment Process ◽  
Post Heat Treatment ◽  
Intraocular Surgery ◽  
Osteoinductive Potential ◽  
3D Printed

PMMA, PC, and PEEK are thermoplastic polymers that possess favorable properties for biomedical applications. These polymers have been used in fields of maxillo-facial, orthopedic, intraocular surgery, and bio-implant, due to their excellent mechanical properties, osteoinductive potential, and antimicrobial capabilities. In this study, the effect of heat treatment on the mechanical properties of 3D printed polymers was characterized. By modifying printing temperature and post heat treatment process, the mechanical properties were specifically tailored for different applications, correlating with the properties of the implants that are commonly made using molding processes.

scholarly journals DLP 3D Printing Meets Lignocellulosic Biopolymers: Carboxymethyl Cellulose Inks for 3D Biocompatible Hydrogels

Polymers ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 1655 ◽  
Author(s):  
Giuseppe Melilli ◽  
Irene Carmagnola ◽  
Chiara Tonda-Turo ◽  
Fabrizio Pirri ◽  
Gianluca Ciardelli ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Additive Manufacturing ◽  
3D Printing ◽  
Carboxymethyl Cellulose ◽  
Biomedical Applications ◽  
Digital Light Processing ◽  
Chemically Modified ◽  
Significant Step ◽  
3D Printed ◽  
Biomedical Field

The development of new bio-based inks is a stringent request for the expansion of additive manufacturing towards the development of 3D-printed biocompatible hydrogels. Herein, methacrylated carboxymethyl cellulose (M-CMC) is investigated as a bio-based photocurable ink for digital light processing (DLP) 3D printing. CMC is chemically modified using methacrylic anhydride. Successful methacrylation is confirmed by 1H NMR and FTIR spectroscopy. Aqueous formulations based on M-CMC/lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP) photoinitiator and M-CMC/Dulbecco’s Modified Eagle Medium (DMEM)/LAP show high photoreactivity upon UV irradiation as confirmed by photorheology and FTIR. The same formulations can be easily 3D-printed through a DLP apparatus to produce 3D shaped hydrogels with excellent swelling ability and mechanical properties. Envisaging the application of the hydrogels in the biomedical field, cytotoxicity is also evaluated. The light-induced printing of cellulose-based hydrogels represents a significant step forward in the production of new DLP inks suitable for biomedical applications.

3D Printed PLA/PCL/TiO2 Composite for Bone Replacement and Grafting

MRS Advances ◽  
2018 ◽  
Vol 3 (40) ◽  
pp. 2373-2378 ◽  
Author(s):  
Sandra E. Nájera ◽  
Monica Michel ◽  
Nam-Soo Kim
Keyword(s):  
Biomedical Applications ◽  
Fused Deposition Modeling ◽  
Fracture Strain ◽  
Fused Deposition ◽  
In Vitro Biocompatibility ◽  
Bone Replacement ◽  
Deposition Modeling ◽  
3D Printed ◽  
The Stability

ABSTRACTPolymer composites of Polylactic acid (PLA) and poly-ε-caprolactone (PCL), containing small amounts of titanium oxide (TiO2) were developed for biomedical applications. These composite materials were prepared, and then printed using Fused Deposition Modeling (FDM). 3D printed structures were characterized to determine their mechanical properties and biocompatibility. DSC analysis yielded useful information regarding the immiscibility of the different polymers, and it was observed that the particles of TiO2 improved the stability of the polymers. The ultimate tensile strength and the fracture strain increased by adding TiO2 as a filler, resulting in values of approximately 45 MPa and 5.5 % elongation. The printed composites show excellent in vitro biocompatibility including cell proliferation and adhesion, and are therefore promising candidates to be used in the biomedical field for bone replacement procedures, due to their properties similar to those of cancellous bone.

scholarly journals Effect of environment on mechanical properties of 3D printed polylactide for biomedical applications

2020 ◽  
Vol 102 ◽  
pp. 103510 ◽  
Author(s):  
Amirpasha Moetazedian ◽  
Andrew Gleadall ◽  
Xiaoxiao Han ◽  
Vadim V. Silberschmidt
Keyword(s):  
Mechanical Properties ◽  
Biomedical Applications ◽  
3D Printed

scholarly journals 3D printed Mg-NiTi interpenetrating-phase composites with high strength, damping capacity, and energy absorption efficiency

2020 ◽  
Vol 6 (19) ◽  
pp. eaba5581 ◽  
Author(s):  
Mingyang Zhang ◽  
Qin Yu ◽  
Zengqian Liu ◽  
Jian Zhang ◽  
Guoqi Tan ◽  
...  
Keyword(s):  
Energy Absorption ◽  
Biomedical Applications ◽  
Elevated Temperatures ◽  
High Strength ◽  
Absorption Efficiency ◽  
Damping Capacity ◽  
Energy Absorption Efficiency ◽  
3D Printed ◽  
New Perspective ◽  
Magnesium Melt

It is of significance, but still remains a key challenge, to simultaneously enhance the strength and damping capacities in metals, as these two properties are often mutually exclusive. Here, we provide a multidesign strategy for defeating such a conflict by developing a Mg-NiTi composite with a bicontinuous interpenetrating-phase architecture through infiltration of magnesium melt into three-dimensionally printed Nitinol scaffold. The composite exhibits a unique combination of mechanical properties with improved strengths at ambient to elevated temperatures, remarkable damage tolerance, good damping capacities at differing amplitudes, and exceptional energy absorption efficiency, which is unprecedented for magnesium materials. The shape and strength after deformation can even be largely recovered by heat treatment. This study offers a new perspective for the structural and biomedical applications of magnesium.

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