scholarly journals A Novel Clinical Radiomics Nomogram to Identify Crohn’s Disease from Intestinal Tuberculosis

2021 ◽  
Vol Volume 14 ◽  
pp. 6511-6521
Author(s):  
Chao Zhu ◽  
Yongmei Yu ◽  
Shihui Wang ◽  
Xia Wang ◽  
Yankun Gao ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Intestinal Tuberculosis

scholarly journals P298 Crohn’s disease or intestinal tuberculosis: The unsolved enigma

2018 ◽  
Vol 12 (supplement_1) ◽  
pp. S251-S251
Author(s):  
N Elleuch ◽  
W Dahmani ◽  
A Ben Slama ◽  
A Hammami ◽  
H Jaziri ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Intestinal Tuberculosis

476 CT Based Predictive Model for Differentiation of Crohn's Disease From Intestinal Tuberculosis

2013 ◽  
Vol 144 (5) ◽  
pp. S-86-S-87 ◽  
Author(s):  
Saurabh Kedia ◽  
Raju Sharma ◽  
Birinder Nagi ◽  
Pratap Mouli Venigalla ◽  
Rajan Dhingra ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Predictive Model ◽  
Intestinal Tuberculosis

scholarly journals Recent advancements in management of gastrointestinal tuberculosis

2018 ◽  
Vol 5 (9) ◽  
pp. 3730
Author(s):  
Basim F. Khan ◽  
Ahmed M. Basha ◽  
Bandar R. Bakhurji ◽  
Bader J. Aldossari ◽  
Abdulaziz S. Alsumaihi ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Good Accuracy ◽  
Clinical Presentation ◽  
Intestinal Tuberculosis ◽  
Scoring Systems ◽  
Abdominal Tuberculosis ◽  
Diagnostic Challenge ◽  
Important Concern ◽  
Diagnostic Modalities

Abdominal tuberculosis and its protean manifestations still create a worldwide diagnostic challenge for clinicians and remain an important concern in the developing world. Crohn’s disease, which is being increasingly recognized in countries where intestinal tuberculosis is prevalent, needs to be differentiated as the two diseases resemble each other in their clinical presentation, and in their radiological, endoscopic, and histological findings. New diagnostic modalities and scoring systems have facilitated the differentiation of Crohn’s disease from intestinal tuberculosis with good accuracy. Randomized trials have shown 6 months of therapy to be equivalent to longer durations of treatment for patients with abdominal tuberculosis. 

scholarly journals Role of Colonoscopy in Differentiating Intestinal Tuberculosis from Crohn’s Disease

2017 ◽  
Vol 08 (02) ◽  
pp. 072-077 ◽  
Author(s):  
P. Rajesh Prabhu ◽  
Mayank Jain ◽  
Piyush Bawane ◽  
Joy Varghese ◽  
Jayanthi Venkataraman
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Statistical Tests ◽  
Intestinal Tuberculosis ◽  
Aphthous Ulcer ◽  
Tb Treatment ◽  
Respective Treatment ◽  
Skip Lesions ◽  
Histological Confirmation

ABSTRACT Background: The interface between tuberculosis (TB) and Crohn’s disease (CD) is relevant as TB complicates both the diagnosis and management of CD. Aim: This study aimed to identify the distinctive characteristics of ileocaecal and colonic TB (C‑TB) and colonic CD (C‑CD) at colonoscopy and to correlate the colonoscopy findings with histology. Materials and Methods: This prospective study included consecutive patients presenting with classical symptoms of TB or CD. The colonoscopic findings were compared with histology, which was taken as gold standard. Appropriate statistical tests were applied. Results: Fifty‑eight individuals fulfilled the inclusion criteria. Nine and 16 patients with C‑TB and C‑CD, respectively, had histological confirmation of respective diagnosis. In 33 specimens, the histological diagnosis was inconclusive. The sensitivity of colonoscopy for diagnosing C‑TB was high at 88.9% (95% confidence interval [CI]: 51.8–99.7). It was 50% (95% CI: 24.7–75.4) for CD. The reverse was true for CD whose specificity was high at 71.4% (95% CI: 55.3–84.3) and low for TB at 46.9% (95% CI: 32.5–61.7). All the patients diagnosed as confirmed CD or TB responded well to respective treatment. Six of the thirty patients with failed response to anti‑TB treatment required surgery or change in treatment after 2 months. Conclusion: Colonoscopic findings of isolated ileal involvement, aphthous ulcer, cobble stoning, long‑segment strictures, skip lesions and perianal involvement favored a diagnosis of CD. Correlation of colonoscopy with histology is poor for both CD and TB. The accuracy, sensitivity and specificity of colonoscopy were better and superior for the diagnosis of CD, than in the diagnosis of TB.

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